ENSG00000185668


Homo sapiens

Features
Gene ID: ENSG00000185668
  
Biological name :POU3F1
  
Synonyms : POU3F1 / POU class 3 homeobox 1 / Q03052
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p34.3
Gene start: 38044611
Gene end: 38046794
  
Corresponding Affymetrix probe sets: 208345_s_at (Human Genome U133 Plus 2.0 Array)   210475_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000362103
NCBI entrez gene - 5453     See in Manteia.
OMIM - 602479
RefSeq - NM_002699
RefSeq Peptide - NP_002690
swissprot - Q03052
Ensembl - ENSG00000185668
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pou3f1ENSDARG00000009823Danio rerio
 P21952ENSMUSG00000090125Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P20264 / POU3F3 / POU class 3 homeobox 3ENSG0000019891455
P20265 / POU3F2 / POU class 3 homeobox 2ENSG0000018448651
P49335 / POU3F4 / POU class 3 homeobox 4ENSG0000019676743
P09086 / POU2F2 / POU class 2 homeobox 2ENSG0000002827730
P14859 / POU2F1 / POU class 2 homeobox 1ENSG0000014319029
POU2F3 / Q9UKI9 / POU class 2 homeobox 3ENSG0000013770928
Q06416 / POU5F1B / POU class 5 homeobox 1BENSG0000021299326
POU5F1 / Q01860 / POU class 5 homeobox 1ENSG0000020453126
POU4F1 / Q01851 / POU class 4 homeobox 1ENSG0000015219222
P28069 / POU1F1 / POU class 1 homeobox 1ENSG0000006483522
POU4F3 / Q15319 / POU class 4 homeobox 3ENSG0000009101021
POU4F2 / Q12837 / POU class 4 homeobox 2ENSG0000015161521
POU5F2 / Q8N7G0 / POU domain class 5, transcription factor 2ENSG0000024848319


Protein motifs (from Interpro)
Interpro ID Name
 IPR000327  POU-specific domain
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR010982  Lambda repressor-like, DNA-binding domain superfamily
 IPR013847  POU domain
 IPR016362  POU-domain transcription factor, class 3
 IPR017970  Homeobox, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0007420 brain development IEA
 biological_processGO:0008366 axon ensheathment TAS
 biological_processGO:0008544 epidermis development IEA
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0014044 Schwann cell development IEA
 biological_processGO:0022011 myelination in peripheral nervous system IEA
 biological_processGO:0030216 keratinocyte differentiation IEA
 biological_processGO:0030900 forebrain development IEA
 biological_processGO:0042552 myelination IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 cellular_componentGO:0005634 nucleus ISS
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005667 transcription factor complex IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity TAS
 molecular_functionGO:0043565 sequence-specific DNA binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr