ENSG00000184486


Homo sapiens

Features
Gene ID: ENSG00000184486
  
Biological name :POU3F2
  
Synonyms : P20265 / POU3F2 / POU class 3 homeobox 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: 1
Band: q16.1
Gene start: 98834592
Gene end: 98839470
  
Corresponding Affymetrix probe sets: 207084_at (Human Genome U133 Plus 2.0 Array)   242455_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000329170
NCBI entrez gene - 5454     See in Manteia.
OMIM - 600494
RefSeq - NM_005604
RefSeq Peptide - NP_005595
swissprot - P20265
Ensembl - ENSG00000184486
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 P79746ENSDARG00000076262Danio rerio
 POU3F2ENSGALG00000038425Gallus gallus
 P31360ENSMUSG00000095139Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P20264 / POU3F3 / POU class 3 homeobox 3ENSG0000019891461
POU3F1 / Q03052 / POU class 3 homeobox 1ENSG0000018566852
P49335 / POU3F4 / POU class 3 homeobox 4ENSG0000019676751
P09086 / POU2F2 / POU class 2 homeobox 2ENSG0000002827731
P14859 / POU2F1 / POU class 2 homeobox 1ENSG0000014319031
POU2F3 / Q9UKI9 / POU class 2 homeobox 3ENSG0000013770930
POU5F1 / Q01860 / POU class 5 homeobox 1ENSG0000020453126
Q06416 / POU5F1B / POU class 5 homeobox 1BENSG0000021299325
P28069 / POU1F1 / POU class 1 homeobox 1ENSG0000006483523
POU4F3 / Q15319 / POU class 4 homeobox 3ENSG0000009101022
POU4F1 / Q01851 / POU class 4 homeobox 1ENSG0000015219222
POU4F2 / Q12837 / POU class 4 homeobox 2ENSG0000015161521
POU5F2 / Q8N7G0 / POU domain class 5, transcription factor 2ENSG0000024848319


Protein motifs (from Interpro)
Interpro ID Name
 IPR000327  POU-specific domain
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR010982  Lambda repressor-like, DNA-binding domain superfamily
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR013847  POU domain
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR016362  POU-domain transcription factor, class 3
 IPR017970  Homeobox, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II ISS
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0007399 nervous system development ISS
 biological_processGO:0007420 brain development IEA
 biological_processGO:0008284 positive regulation of cell proliferation IDA
 biological_processGO:0008544 epidermis development IEA
 biological_processGO:0010629 negative regulation of gene expression IEA
 biological_processGO:0014002 astrocyte development IEA
 biological_processGO:0014044 Schwann cell development IEA
 biological_processGO:0021799 cerebral cortex radially oriented cell migration IEA
 biological_processGO:0021869 forebrain ventricular zone progenitor cell division IEA
 biological_processGO:0021979 hypothalamus cell differentiation IEA
 biological_processGO:0021985 neurohypophysis development IEA
 biological_processGO:0022011 myelination in peripheral nervous system IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0030182 neuron differentiation IEA
 biological_processGO:0040018 positive regulation of multicellular organism growth IEA
 biological_processGO:0045595 regulation of cell differentiation IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0048663 neuron fate commitment IEA
 biological_processGO:0048665 neuron fate specification IEA
 biological_processGO:0048666 neuron development IEA
 biological_processGO:0050770 regulation of axonogenesis IEA
 biological_processGO:0071310 cellular response to organic substance IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005667 transcription factor complex IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr