ENSG00000137709


Homo sapiens

Features
Gene ID: ENSG00000137709
  
Biological name :POU2F3
  
Synonyms : POU2F3 / POU class 2 homeobox 3 / Q9UKI9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: 1
Band: q23.3
Gene start: 120236640
Gene end: 120319944
  
Corresponding Affymetrix probe sets: 207109_at (Human Genome U133 Plus 2.0 Array)   215355_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000453150
Ensembl peptide - ENSP00000260264
Ensembl peptide - ENSP00000435738
Ensembl peptide - ENSP00000441687
NCBI entrez gene - 25833     See in Manteia.
OMIM - 607394
RefSeq - XM_017017487
RefSeq - XM_011542739
RefSeq - XM_011542740
RefSeq - XM_011542741
RefSeq - XM_011542742
RefSeq - XM_011542743
RefSeq - NM_001244682
RefSeq - NM_014352
RefSeq Peptide - NP_001231611
RefSeq Peptide - NP_055167
swissprot - H0YLC5
swissprot - Q9UKI9
swissprot - E9PIN6
Ensembl - ENSG00000137709
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pou2f3ENSDARG00000052387Danio rerio
 POU2F3ENSGALG00000006673Gallus gallus
 Pou2f3ENSMUSG00000032015Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P14859 / POU2F1 / POU class 2 homeobox 1ENSG0000014319050
P09086 / POU2F2 / POU class 2 homeobox 2ENSG0000002827748
P20264 / POU3F3 / POU class 3 homeobox 3ENSG0000019891432
P49335 / POU3F4 / POU class 3 homeobox 4ENSG0000019676730
P20265 / POU3F2 / POU class 3 homeobox 2ENSG0000018448630
POU3F1 / Q03052 / POU class 3 homeobox 1ENSG0000018566829
POU5F1 / Q01860 / POU class 5 homeobox 1ENSG0000020453129
Q06416 / POU5F1B / POU class 5 homeobox 1BENSG0000021299328
P28069 / POU1F1 / POU class 1 homeobox 1ENSG0000006483524
POU4F1 / Q01851 / POU class 4 homeobox 1ENSG0000015219223
POU4F3 / Q15319 / POU class 4 homeobox 3ENSG0000009101023
POU4F2 / Q12837 / POU class 4 homeobox 2ENSG0000015161522
POU5F2 / Q8N7G0 / POU domain class 5, transcription factor 2ENSG0000024848320


Protein motifs (from Interpro)
Interpro ID Name
 IPR000327  POU-specific domain
 IPR000972  Octamer-binding transcription factor
 IPR001356  Homeobox domain
 IPR001387  Cro/C1-type helix-turn-helix domain
 IPR009057  Homeobox-like domain superfamily
 IPR010982  Lambda repressor-like, DNA-binding domain superfamily
 IPR013847  POU domain
 IPR017970  Homeobox, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II TAS
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0008544 epidermis development TAS
 biological_processGO:0043922 negative regulation by host of viral transcription IDA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IMP
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IMP
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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