ENSGALG00000004293


Gallus gallus

Features
Gene ID: ENSGALG00000004293
  
Biological name :
  
Synonyms :
  
Possible biological names infered from orthology : lipoprotein(a) / LPA / P00747 / P08519 / P20918 / plasminogen / Plasminogen Plasmin heavy chain A Activation peptide Angiostatin Plasmin heavy chain A, short form Plasmin light chain B / PLG
  
Species: Gallus gallus
  
Chr. number: 3
Strand: 1
Band:
Gene start: 45526014
Gene end: 45546436
  
Corresponding Affymetrix probe sets: Gga.4114.1.S1_at (Chicken Array)   GgaAffx.26160.1.S1_s_at (Chicken Array)   GgaAffx.2657.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000006818
NCBI entrez gene - 421580     See in Manteia.
RefSeq - XM_419618
swissprot - F1NWX6
Ensembl - ENSGALG00000004293
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 plgENSDARG00000023111Danio rerio
 LPAENSG00000198670Homo sapiens
 PLGENSG00000122194Homo sapiens
 PlgENSMUSG00000059481Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LPA* / PLG* / P00747* / P08519* / P20918* / plasminogen* / lipoprotein(a)* / Plasminogen Plasmin heavy chain A Activation peptide Angiostatin Plasmin heavy chain A, short form Plasmin light chain B*ENSGALG0000002888662
MST1 / hepatocyte growth factor-like protein precursor / P26928* / macrophage stimulating 1* / macrophage stimulating 1 (hepatocyte growth factor-like)*ENSGALG0000000272235
HGF / hepatocyte growth factor / P14210* / Q08048* / Hepatocyte growth factor Hepatocyte growth factor alpha chain Hepatocyte growth factor beta chain*ENSGALG0000003397434
HGFAC / HGF activator / Q04756* / Q9R098* / hepatocyte growth factor activator*ENSGALG0000001562322
F2 / prothrombin precursor / P00734* / P19221* / coagulation factor II, thrombin* / Prothrombin Activation peptide fragment 1 Activation peptide fragment 2 Thrombin light chain Thrombin heavy chain*ENSGALG0000000833222
PLAT / plasminogen activator, tissue type / P00750* / P11214* / Tissue-type plasminogen activator Tissue-type plasminogen activator chain A Tissue-type plasminogen activator chain B*ENSGALG0000000370920
HABP2 / hyaluronan-binding protein 2 preproprotein / Q14520* / hyaluronan binding protein 2* / Mus musculus hyaluronic acid binding protein 2 (Habp2), transcript variant 1, mRNA.*ENSGALG0000000890518
PLAU / plasminogen activator, urokinase / P00749* / P06869*ENSGALG0000000508616


Protein motifs (from Interpro)
Interpro ID Name
 IPR000001  Kringle
 IPR001254  Serine proteases, trypsin domain
 IPR001314  Peptidase S1A, chymotrypsin family
 IPR003609  PAN/Apple domain
 IPR009003  Peptidase S1, PA clan
 IPR013806  Kringle-like fold
 IPR018056  Kringle, conserved site
 IPR018114  Serine proteases, trypsin family, histidine active site
 IPR023317  Peptidase S1A, plasmin
 IPR033116  Serine proteases, trypsin family, serine active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0007596 blood coagulation IEA
 biological_processGO:0007599 hemostasis IEA
 biological_processGO:0042730 fibrinolysis IEA
 biological_processGO:0048771 tissue remodeling IEA
 cellular_componentGO:0005576 extracellular region IEA
 molecular_functionGO:0004252 serine-type endopeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008236 serine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Platelet degranulation
Degradation of the extracellular matrix
Activation of Matrix Metalloproteinases
Signaling by PDGF
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Dissolution of Fibrin Clot
LDL remodeling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000037940 IGFBP3 / insulin like growth factor binding protein 3 / P17936* / P47878*  / reaction
 ENSGALG00000003709 PLAT / plasminogen activator, tissue type / P00750* / P11214* / Tissue-type plasminogen activator Tissue-type plasminogen activator chain A Tissue-type plasminogen activator chain B*  / reaction / complex
 ENSGALG00000004293 LPA* / PLG* / P00747* / P08519* / P20918* / plasminogen* / lipoprotein(a)* / Plasminogen Plasmin heavy chain A Activation peptide Angiostatin Plasmin heavy chain A, short form Plasmin light chain B*  / complex
 ENSGALG00000035282 IGF2 / P33717 / Insulin-like growth factor II / P01344* / P09535* / insulin like growth factor 2* / Insulin-like growth factor II Insulin-like growth factor II Preptin*  / reaction
 ENSGALG00000028886 LPA* / PLG* / P00747* / P08519* / P20918* / plasminogen* / lipoprotein(a)* / Plasminogen Plasmin heavy chain A Activation peptide Angiostatin Plasmin heavy chain A, short form Plasmin light chain B*  / complex
 ENSGALG00000012755 IGF-I / P18254 / Insulin-like growth factor I / IGF1* / P05017* / P05019* / insulin like growth factor 1*  / reaction
 ENSGALG00000017183 MMP13 / collagenase 3 precursor / P45452* / P33435* / Collagenase 3 * / matrix metallopeptidase 13*  / reaction
 ENSGALG00000017179 PDGFD / platelet derived growth factor D / Q925I7* / Q9GZP0* / Mus musculus platelet-derived growth factor, D polypeptide (Pdgfd), transcript variant 2, mRNA.*  / reaction
 ENSGALG00000009378 PDGFC / Q9I946 / Platelet-derived growth factor C Platelet-derived growth factor C, latent form Platelet-derived growth factor C, receptor-binding form / Q9NRA1* / Q8CI19* / platelet derive...  / reaction






 

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