ENSMUSG00000007379


Mus musculus

Features
Gene ID: ENSMUSG00000007379
  
Biological name :Dennd2c
  
Synonyms : Dennd2c / DENN domain containing 2C
  
Possible biological names infered from orthology : Q68D51
  
Species: Mus musculus
  
Chr. number: 3
Strand: 1
Band: F2.2
Gene start: 103102604
Gene end: 103169769
  
Corresponding Affymetrix probe sets: 10494889 (MoGene1.0st)   1456891_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000127187
Ensembl peptide - ENSMUSP00000134008
NCBI entrez gene - 329727     See in Manteia.
MGI - MGI:3036254
RefSeq - XM_017319624
RefSeq - XM_006501604
RefSeq - XM_006501605
RefSeq - XM_006501606
RefSeq - NM_177857
RefSeq - XM_006501600
RefSeq - XM_006501602
RefSeq Peptide - NP_808525
swissprot - G3UYA7
swissprot - E9Q4E4
Ensembl - ENSMUSG00000007379
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dennd2cENSDARG00000073738Danio rerio
 DENND2CENSGALG00000002038Gallus gallus
 Q68D51ENSG00000175984Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8C4S8 / Dennd2a / DENN domain-containing protein 2A / Q9ULE3* / DENN domain containing 2A*ENSMUSG0000003845646
St5 / Q924W7 / Suppression of tumorigenicity 5 protein / P78524* / suppression of tumorigenicity 5*ENSMUSG0000003102445
Q91VV4 / Dennd2d / DENN domain-containing protein 2D / Q9H6A0* / DENN domain containing 2D*ENSMUSG0000002790124
Q3U1Y4 / Dennd4b / Mus musculus DENN/MADD domain containing 4B (Dennd4b), transcript variant 2, mRNA. / O75064* / DENN domain containing 4B*ENSMUSG0000004240415
Dennd4a / DENN domain containing 4A / Q7Z401*ENSMUSG0000005364114
A6H8H2 / Dennd4c / DENN domain-containing protein 4C / Q5VZ89* / DENN domain containing 4C*ENSMUSG0000003802414
Q3U1T9 / Dennd1b / DENN domain-containing protein 1B / Q6P3S1* / DENN domain containing 1B*ENSMUSG0000005626813
Q8K382 / Dennd1a / DENN domain-containing protein 1A / Q8TEH3* / DENN domain containing 1A*ENSMUSG0000003539213
A2RT67 / Dennd3 / DENN domain-containing protein 3 / A2RUS2* / DENN domain containing 3*ENSMUSG0000003666112
Q8CFK6 / Dennd1c / DENN domain-containing protein 1C / Q8IV53* / DENN domain containing 1C*ENSMUSG0000000266812
A2RSQ0 / Dennd5b / DENN domain-containing protein 5B / Q6ZUT9* / DENN domain containing 5B*ENSMUSG0000003031312
Q6PAL8 / Dennd5a / DENN domain-containing protein 5A / Q6IQ26* / DENN domain containing 5A*ENSMUSG0000003590111
Madd / MAP-kinase activating death domain / Q8WXG6*ENSMUSG0000004068710


Protein motifs (from Interpro)
Interpro ID Name
 IPR001194  cDENN domain
 IPR005112  dDENN domain
 IPR005113  uDENN domain
 IPR037516  Tripartite DENN domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0065009 regulation of molecular function IEA
 molecular_functionGO:0017112 Rab guanyl-nucleotide exchange factor activity IEA


Pathways (from Reactome)
Pathway description
RAB GEFs exchange GTP for GDP on RABs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0010570 prolonged ST segment "increase in the length of time between the end of S-wave and the beginning of T-wave; reflects the amount of time the ventricles remain electrically depolarized" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
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Allelic Composition: Cecr2tm2b(EUCOMM)Hmgu/Cecr2+
Genetic Background: C57BL/6N-Cecr2tm2b(EUCOMM)Hmgu/Tcp

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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