ENSG00000175984


Homo sapiens

Features
Gene ID: ENSG00000175984
  
Biological name :DENND2C
  
Synonyms : DENND2C / DENN domain containing 2C / Q68D51
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p13.2
Gene start: 114582848
Gene end: 114670422
  
Corresponding Affymetrix probe sets: 230769_at (Human Genome U133 Plus 2.0 Array)   233294_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000376955
Ensembl peptide - ENSP00000376957
Ensembl peptide - ENSP00000376958
NCBI entrez gene - 163259     See in Manteia.
RefSeq - NM_001256404
RefSeq - NM_198459
RefSeq Peptide - NP_001243333
RefSeq Peptide - NP_940861
swissprot - Q68D51
Ensembl - ENSG00000175984
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dennd2cENSDARG00000073738Danio rerio
 DENND2CENSGALG00000002038Gallus gallus
 Dennd2cENSMUSG00000007379Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9ULE3 / DENND2A / DENN domain containing 2AENSG0000014696647
ST5 / P78524 / suppression of tumorigenicity 5ENSG0000016644446
Q9H6A0 / DENND2D / DENN domain containing 2DENSG0000016277724
Q5VZ89 / DENND4C / DENN domain containing 4CENSG0000013714515
O75064 / DENND4B / DENN domain containing 4BENSG0000019883715
Q7Z401 / DENND4A / DENN domain containing 4AENSG0000017448515
Q8TEH3 / DENND1A / DENN domain containing 1AENSG0000011952213
Q6P3S1 / DENND1B / DENN domain containing 1BENSG0000021304713
Q6ZUT9 / DENND5B / DENN domain containing 5BENSG0000017045612
Q6IQ26 / DENND5A / DENN domain containing 5AENSG0000018401412
Q8IV53 / DENND1C / DENN domain containing 1CENSG0000020574412
A2RUS2 / DENND3 / DENN domain containing 3ENSG0000010533911
MADD / Q8WXG6 / MAP kinase activating death domainENSG0000011051410


Protein motifs (from Interpro)
Interpro ID Name
 IPR001194  cDENN domain
 IPR005112  dDENN domain
 IPR005113  uDENN domain
 IPR037516  Tripartite DENN domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0065009 regulation of molecular function IEA
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0017112 Rab guanyl-nucleotide exchange factor activity IDA


Pathways (from Reactome)
Pathway description
RAB GEFs exchange GTP for GDP on RABs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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