ENSG00000162777


Homo sapiens

Features
Gene ID: ENSG00000162777
  
Biological name :DENND2D
  
Synonyms : DENND2D / DENN domain containing 2D / Q9H6A0
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p13.2
Gene start: 111187174
Gene end: 111204535
  
Corresponding Affymetrix probe sets: 221081_s_at (Human Genome U133 Plus 2.0 Array)   235986_at (Human Genome U133 Plus 2.0 Array)   238524_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000350266
Ensembl peptide - ENSP00000358767
NCBI entrez gene - 79961     See in Manteia.
OMIM - 615111
RefSeq - XM_017002388
RefSeq - XM_011542187
RefSeq - XM_011542189
RefSeq - XM_011542190
RefSeq - XM_017002386
RefSeq - XM_017002387
RefSeq - NM_001271833
RefSeq - NM_024901
RefSeq - XM_006710921
RefSeq - XM_006710922
RefSeq - XM_006710923
RefSeq - XM_006710924
RefSeq Peptide - NP_001258762
RefSeq Peptide - NP_079177
swissprot - A0A024R0H5
swissprot - Q9H6A0
swissprot - A0A024R0G2
Ensembl - ENSG00000162777
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dennd2daENSDARG00000058666Danio rerio
 dennd2dbENSDARG00000030250Danio rerio
 DENND2DENSGALG00000000154Gallus gallus
 Q91VV4ENSMUSG00000027901Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ST5 / P78524 / suppression of tumorigenicity 5ENSG0000016644448
Q68D51 / DENND2C / DENN domain containing 2CENSG0000017598447
Q9ULE3 / DENND2A / DENN domain containing 2AENSG0000014696647
Q5VZ89 / DENND4C / DENN domain containing 4CENSG0000013714523
Q6P3S1 / DENND1B / DENN domain containing 1BENSG0000021304723
Q7Z401 / DENND4A / DENN domain containing 4AENSG0000017448523
Q8TEH3 / DENND1A / DENN domain containing 1AENSG0000011952222
Q8IV53 / DENND1C / DENN domain containing 1CENSG0000020574422
O75064 / DENND4B / DENN domain containing 4BENSG0000019883721
Q6ZUT9 / DENND5B / DENN domain containing 5BENSG0000017045620
A2RUS2 / DENND3 / DENN domain containing 3ENSG0000010533919
Q6IQ26 / DENND5A / DENN domain containing 5AENSG0000018401419
MADD / Q8WXG6 / MAP kinase activating death domainENSG0000011051418


Protein motifs (from Interpro)
Interpro ID Name
 IPR001194  cDENN domain
 IPR005112  dDENN domain
 IPR005113  uDENN domain
 IPR037516  Tripartite DENN domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0065009 regulation of molecular function IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0017112 Rab guanyl-nucleotide exchange factor activity IDA


Pathways (from Reactome)
Pathway description
RAB GEFs exchange GTP for GDP on RABs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr