ENSMUSG00000053641


Mus musculus

Features
Gene ID: ENSMUSG00000053641
  
Biological name :Dennd4a
  
Synonyms : Dennd4a / DENN domain containing 4A
  
Possible biological names infered from orthology : Q7Z401
  
Species: Mus musculus
  
Chr. number: 9
Strand: 1
Band: C
Gene start: 64811340
Gene end: 64919667
  
Corresponding Affymetrix probe sets: 10586227 (MoGene1.0st)   10586240 (MoGene1.0st)   10586242 (MoGene1.0st)   10586244 (MoGene1.0st)   10586246 (MoGene1.0st)   10586248 (MoGene1.0st)   10586250 (MoGene1.0st)   10586252 (MoGene1.0st)   10586254 (MoGene1.0st)   1435975_at (Mouse Genome 430 2.0 Array)   1446558_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000150918
Ensembl peptide - ENSMUSP00000037915
NCBI entrez gene - 102442     See in Manteia.
MGI - MGI:2142979
RefSeq - XM_011242654
RefSeq - XM_011242651
RefSeq - XM_011242652
RefSeq - XM_011242653
RefSeq - NM_001162917
RefSeq - XM_006510741
RefSeq - XM_006510742
RefSeq - XM_006510743
RefSeq - XM_006510744
RefSeq - XM_006510745
RefSeq Peptide - NP_001156389
swissprot - E9Q8V6
swissprot - A0A1L1SUW5
Ensembl - ENSMUSG00000053641
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dennd4aENSDARG00000062721Danio rerio
 DENND4AENSGALG00000041403Gallus gallus
 Q7Z401ENSG00000174485Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
A6H8H2 / Dennd4c / DENN domain-containing protein 4C / Q5VZ89* / DENN domain containing 4C*ENSMUSG0000003802450
Q3U1Y4 / Dennd4b / Mus musculus DENN/MADD domain containing 4B (Dennd4b), transcript variant 2, mRNA. / O75064* / DENN domain containing 4B*ENSMUSG0000004240438
Madd / MAP-kinase activating death domain / Q8WXG6*ENSMUSG0000004068715
Q6PAL8 / Dennd5a / DENN domain-containing protein 5A / Q6IQ26* / DENN domain containing 5A*ENSMUSG0000003590112
A2RSQ0 / Dennd5b / DENN domain-containing protein 5B / Q6ZUT9* / DENN domain containing 5B*ENSMUSG0000003031312
Q8K382 / Dennd1a / DENN domain-containing protein 1A / Q8TEH3* / DENN domain containing 1A*ENSMUSG0000003539210
A2RT67 / Dennd3 / DENN domain-containing protein 3 / A2RUS2* / DENN domain containing 3*ENSMUSG0000003666110
Q8C4S8 / Dennd2a / DENN domain-containing protein 2A / Q9ULE3* / DENN domain containing 2A*ENSMUSG000000384568
Q3U1T9 / Dennd1b / DENN domain-containing protein 1B / Q6P3S1* / DENN domain containing 1B*ENSMUSG000000562688
St5 / Q924W7 / Suppression of tumorigenicity 5 protein / P78524* / suppression of tumorigenicity 5*ENSMUSG000000310248
Q8CFK6 / Dennd1c / DENN domain-containing protein 1C / Q8IV53* / DENN domain containing 1C*ENSMUSG000000026688
Dennd2c / DENN domain containing 2C / Q68D51*ENSMUSG000000073797
Q91VV4 / Dennd2d / DENN domain-containing protein 2D / Q9H6A0* / DENN domain containing 2D*ENSMUSG000000279016


Protein motifs (from Interpro)
Interpro ID Name
 IPR001194  cDENN domain
 IPR002885  Pentatricopeptide repeat
 IPR005112  dDENN domain
 IPR005113  uDENN domain
 IPR023341  MABP domain
 IPR037516  Tripartite DENN domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0065009 regulation of molecular function IEA
 cellular_componentGO:0005575 cellular_component ND
 molecular_functionGO:0017112 Rab guanyl-nucleotide exchange factor activity ISO


Pathways (from Reactome)
Pathway description
RAB GEFs exchange GTP for GDP on RABs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000015291 Gdi1 / P50396 / Rab GDP dissociation inhibitor alpha / P31150* / GDP dissociation inhibitor 1*  / reaction
 ENSMUSG00000078185 Chml / choroideremia-like / P26374* / CHM like, Rab escort protein 2*  / reaction
 ENSMUSG00000025531 Chm / choroidermia (RAB escort protein 1) / P24386* / CHM, Rab escort protein 1*  / reaction
 ENSMUSG00000020671 Rab10 / P61027 / RAB10, member RAS oncogene family / P61026*  / reaction
 ENSMUSG00000021218 Gdi2 / Q61598 / Rab GDP dissociation inhibitor beta / P50395* / GDP dissociation inhibitor 2*  / reaction






 

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