ENSMUSG00000019804


Mus musculus

Features
Gene ID: ENSMUSG00000019804
  
Biological name :Snx3
  
Synonyms : Snx3 / sorting nexin 3
  
Possible biological names infered from orthology : O60493
  
Species: Mus musculus
  
Chr. number: 10
Strand: 1
Band: B2
Gene start: 42502030
Gene end: 42535381
  
Corresponding Affymetrix probe sets: 10362823 (MoGene1.0st)   1422480_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000019939
Ensembl peptide - ENSMUSP00000101139
Ensembl peptide - ENSMUSP00000101138
NCBI entrez gene - 54198     See in Manteia.
MGI - MGI:1860188
RefSeq - NM_017472
RefSeq Peptide - NP_059500
swissprot - D3Z789
swissprot - D3Z6Z0
swissprot - Q78ZM0
Ensembl - ENSMUSG00000019804
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 snx3ENSDARG00000008678Danio rerio
 SNX3ENSGALG00000015304Gallus gallus
 SNX3ENSG00000112335Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Snx12 / sorting nexin 12 / Q9UMY4*ENSMUSG0000004603277
Snx11 / Q91WL6 / Sorting nexin-11 / Q9Y5W9*ENSMUSG0000002087629
Snx10 / Q9CWT3 / sorting nexin 10 / Q9Y5X0*ENSMUSG0000003830125


Protein motifs (from Interpro)
Interpro ID Name
 IPR001683  Phox homologous domain
 IPR036871  PX domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009617 response to bacterium IEA
 biological_processGO:0010324 membrane invagination IEA
 biological_processGO:0022615 protein to membrane docking IEA
 biological_processGO:0030111 regulation of Wnt signaling pathway IEA
 biological_processGO:0042177 negative regulation of protein catabolic process IEA
 biological_processGO:0046597 negative regulation of viral entry into host cell IEA
 biological_processGO:0050765 negative regulation of phagocytosis IEA
 biological_processGO:0051224 negative regulation of protein transport IEA
 biological_processGO:0070676 intralumenal vesicle formation IEA
 biological_processGO:2000642 negative regulation of early endosome to late endosome transport IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005769 early endosome IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0010008 endosome membrane IEA
 cellular_componentGO:0030136 clathrin-coated vesicle IEA
 cellular_componentGO:0030904 retromer complex IEA
 cellular_componentGO:0031901 early endosome membrane IEA
 cellular_componentGO:0032009 early phagosome IEA
 molecular_functionGO:0019903 protein phosphatase binding IEA
 molecular_functionGO:0032266 phosphatidylinositol-3-phosphate binding IEA
 molecular_functionGO:0035091 phosphatidylinositol binding IEA


Pathways (from Reactome)
Pathway description
WNT ligand biogenesis and trafficking
Ub-specific processing proteases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Rad9atm1.1(KOMP)Wtsi/Rad9atm1.1(KOMP)Wtsi
Genetic Background: C57BL/6N-Rad9atm1.1(KOMP)Wtsi/Bay

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000031826 Usp10 / P52479 / ubiquitin specific peptidase 10 / Q14694*  / complex
 ENSMUSG00000031696 Vps35 / Q9EQH3 / VPS35 retromer complex component / Q96QK1*  / complex / reaction
 ENSMUSG00000028173 Wls / Q6DID7 / wntless WNT ligand secretion mediator / Q5T9L3*  / reaction / complex
 ENSMUSG00000020078 P40336 / Vps26a / VPS26 retromer complex component A / O75436*  / complex / reaction
 ENSMUSG00000029462 Vps29 / Q9QZ88 / VPS29 retromer complex component / Q9UBQ0*  / reaction / complex






 

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