ENSDARG00000008678


Danio rerio

Features
Gene ID: ENSDARG00000008678
  
Biological name :snx3
  
Synonyms : snx3 / sorting nexin 3
  
Possible biological names infered from orthology : O60493
  
Species: Danio rerio
  
Chr. number: 20
Strand: 1
Band:
Gene start: 32406011
Gene end: 32432871
  
Corresponding Affymetrix probe sets: Dr.2953.2.S1_at (Zebrafish Array)   NM_001037106_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000116530
Ensembl peptide - ENSDARP00000012094
NCBI entrez gene - 563511     See in Manteia.
RefSeq - NM_001037106
RefSeq Peptide - NP_001032183
swissprot - B0S7S4
swissprot - Q3B7E7
ZFIN ID - ZDB-GENE-030131-921
Ensembl - ENSDARG00000008678
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SNX3ENSGALG00000015304Gallus gallus
 SNX3ENSG00000112335Homo sapiens
 Snx3ENSMUSG00000019804Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
snx12 / sorting nexin 12 / Q9UMY4*ENSDARG0000001906077
snx11 / sorting nexin 11 / Q91WL6* / Q9Y5W9*ENSDARG0000005252228
snx10a / F1Q506 / sorting nexin 10a / SNX10* / Q9Y5X0* / sorting nexin 10*ENSDARG0000000440527
snx10b / A8WG21 / sorting nexin 10b / SNX10* / Q9Y5X0* / Q9CWT3* / sorting nexin 10*ENSDARG0000004047426
BX571678.1ENSDARG0000011661314


Protein motifs (from Interpro)
Interpro ID Name
 IPR001683  Phox homologous domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006783 heme biosynthetic process IMP
 biological_processGO:0006897 endocytosis IBA
 biological_processGO:0016050 vesicle organization IBA
 biological_processGO:0030218 erythrocyte differentiation IMP
 biological_processGO:0042541 hemoglobin biosynthetic process IMP
 cellular_componentGO:0005768 endosome IBA
 cellular_componentGO:0019898 extrinsic component of membrane IBA
 molecular_functionGO:0035091 phosphatidylinositol binding IEA


Pathways (from Reactome)
Pathway description
WNT ligand biogenesis and trafficking
Ub-specific processing proteases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001094 whole organism whole organism lacks parts or has fewer parts of type nucleate erythrocyte hemoglobin complex, abnormal
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 ZFA:0009256 nucleate erythrocyte nucleate erythrocyte decreased amount , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000009534 wls / wntless Wnt ligand secretion mediator / Q5T9L3* / Q6DID7*  / complex / reaction
 ENSDARG00000056549 Q6TNP8 / vps26a / vacuolar protein sorting 26 homolog A (S. pombe) / O75436* / P40336* / VPS26, retromer complex component A*  / complex / reaction
 ENSDARG00000008224 vps35 / vacuolar protein sorting 35 homolog (S. cerevisiae) / Q96QK1* / Q9EQH3* / VPS35, retromer complex component*  / reaction / complex
 ENSDARG00000069521 vps29 / Q7ZV68 / vacuolar protein sorting 29 homolog (S. cerevisiae) / Q9UBQ0* / Q9QZ88* / VPS29, retromer complex component*  / complex / reaction
 ENSDARG00000103422 usp10 / ubiquitin specific peptidase 10 / P52479* / Q14694*  / complex






 

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contact: otassy@igbmc.fr