ENSMUSG00000020827


Mus musculus

Features
Gene ID: ENSMUSG00000020827
  
Biological name :Mink1
  
Synonyms : Mink1 / misshapen-like kinase 1 (zebrafish) / Q9JM52
  
Possible biological names infered from orthology : misshapen like kinase 1 / Q8N4C8
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: B3
Gene start: 70562881
Gene end: 70614483
  
Corresponding Affymetrix probe sets: 10377889 (MoGene1.0st)   1449362_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000137075
Ensembl peptide - ENSMUSP00000072091
Ensembl peptide - ENSMUSP00000072649
Ensembl peptide - ENSMUSP00000078234
Ensembl peptide - ENSMUSP00000099618
Ensembl peptide - ENSMUSP00000099619
Ensembl peptide - ENSMUSP00000117959
Ensembl peptide - ENSMUSP00000136149
NCBI entrez gene - 50932     See in Manteia.
MGI - MGI:1355329
RefSeq - XM_017314646
RefSeq - NM_001045959
RefSeq - NM_001045964
RefSeq - NM_016713
RefSeq - NM_176893
RefSeq - XM_006533677
RefSeq - XM_006533678
RefSeq - XM_006533679
RefSeq - XM_006533681
RefSeq - XM_006533682
RefSeq - XM_017314645
RefSeq Peptide - NP_795712
RefSeq Peptide - NP_001039424
RefSeq Peptide - NP_001039429
RefSeq Peptide - NP_057922
swissprot - Q5SXG1
swissprot - Q5SXG3
swissprot - Q9JM52
swissprot - F7AMS7
swissprot - J3QM71
swissprot - J3QP32
swissprot - G3X9G2
Ensembl - ENSMUSG00000020827
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mink1ENSDARG00000035360Danio rerio
 MINK1ENSG00000141503Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Tnik / P83510 / TRAF2 and NCK interacting kinase / Q9UKE5*ENSMUSG0000002769266
Map4k4 / mitogen-activated protein kinase kinase kinase kinase 4 / O95819*ENSMUSG0000002607462
Nrk / Q9R0G8 / Nik-related protein kinase / Q7Z2Y5* / Nik related kinase*ENSMUSG0000005285430
Map4k5 / Q8BPM2 / Mitogen-activated protein kinase kinase kinase kinase 5 ENSMUSG0000003476120
Map4k3 / Q99JP0 / Mitogen-activated protein kinase kinase kinase kinase 3 / Q8IVH8*ENSMUSG0000002424220
Map4k1 / P70218 / Mus musculus mitogen-activated protein kinase kinase kinase kinase 1 (Map4k1), transcript variant 2, mRNA. / Q92918* / mitogen-activated protein kinase kinase kinase kinase 1*ENSMUSG0000003733719
Map4k2 / Q61161 / Mitogen-activated protein kinase kinase kinase kinase 2 / Q12851*ENSMUSG0000002494817
Slk / O54988 / STE20-like serine/threonine-protein kinase / Q9H2G2* / STE20 like kinase*ENSMUSG0000002506017
Stk10 / O55098 / Serine/threonine-protein kinase 10 / O94804* / serine/threonine kinase 10*ENSMUSG0000002027215


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR001180  Citron homology (CNH) domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR011989  Armadillo-like helical
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade IEA
 biological_processGO:0000185 activation of MAPKKK activity IEA
 biological_processGO:0001952 regulation of cell-matrix adhesion IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007268 chemical synaptic transmission ISS
 biological_processGO:0007275 multicellular organism development IEP
 biological_processGO:0007346 regulation of mitotic cell cycle IBA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0022407 regulation of cell-cell adhesion IEA
 biological_processGO:0030334 regulation of cell migration IEA
 biological_processGO:0031098 stress-activated protein kinase signaling cascade IBA
 biological_processGO:0031532 actin cytoskeleton reorganization IEA
 biological_processGO:0042981 regulation of apoptotic process IBA
 biological_processGO:0045060 negative thymic T cell selection IMP
 biological_processGO:0046330 positive regulation of JNK cascade IEA
 biological_processGO:0046777 protein autophosphorylation IEA
 biological_processGO:0048812 neuron projection morphogenesis IBA
 biological_processGO:0048813 dendrite morphogenesis ISS
 biological_processGO:1900745 positive regulation of p38MAPK cascade IDA
 biological_processGO:2000311 regulation of AMPA receptor activity ISS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0014069 postsynaptic density IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030424 axon IEA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008349 MAP kinase kinase kinase kinase activity IBA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
Oxidative Stress Induced Senescence


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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