ENSMUSG00000020905


Mus musculus

Features
Gene ID: ENSMUSG00000020905
  
Biological name :Usp43
  
Synonyms : Q8BUM9 / ubiquitin specific peptidase 43 / Usp43
  
Possible biological names infered from orthology : Q70EL4
  
Species: Mus musculus
  
Chr. number: 11
Strand: -1
Band: B3
Gene start: 67854523
Gene end: 67922153
  
Corresponding Affymetrix probe sets: 10387138 (MoGene1.0st)   1424866_at (Mouse Genome 430 2.0 Array)   1451514_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000021288
Ensembl peptide - ENSMUSP00000104317
NCBI entrez gene - 216835     See in Manteia.
MGI - MGI:2444541
RefSeq - XM_017314453
RefSeq - NM_001291049
RefSeq - NM_173754
RefSeq - XM_011248915
RefSeq Peptide - NP_776115
RefSeq Peptide - NP_001277978
swissprot - Q8BUM9
swissprot - A6PWR8
Ensembl - ENSMUSG00000020905
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 usp43aENSDARG00000103494Danio rerio
 usp43bENSDARG00000088072Danio rerio
 ENSGALG00000037812Gallus gallus
 USP43ENSG00000154914Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Usp31 / ubiquitin specific peptidase 31 / Q70CQ4*ENSMUSG0000006331740
Usp19 / Q3UJD6 / ubiquitin specific peptidase 19 / O94966*ENSMUSG0000000667618
Usp4 / P35123 / ubiquitin specific peptidase 4 (proto-oncogene) / Q13107* / ubiquitin specific peptidase 4*ENSMUSG0000003261217
Usp15 / Q8R5H1 / ubiquitin specific peptidase 15 / Q9Y4E8*ENSMUSG0000002012417
Usp32 / ubiquitin specific peptidase 32 / USP6* / P35125* / ubiquitin specific peptidase 6*ENSMUSG0000000080416
Usp11 / Q99K46 / ubiquitin specific peptidase 11 / P51784*ENSMUSG0000003106615


Protein motifs (from Interpro)
Interpro ID Name
 IPR001394  Peptidase C19, ubiquitin carboxyl-terminal hydrolase
 IPR018200  Ubiquitin specific protease, conserved site
 IPR028889  Ubiquitin specific protease domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0016579 protein deubiquitination IEA
 cellular_componentGO:0005634 nucleus IBA
 molecular_functionGO:0004843 thiol-dependent ubiquitin-specific protease activity IBA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0036459 thiol-dependent ubiquitinyl hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Termination of translesion DNA synthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000000751 Rpa1 / Q8VEE4 / Replication protein A 70 kDa DNA-binding subunit / P27694* / replication protein A1*  / complex / reaction
 ENSMUSG00000012483 Rpa3 / Q9CQ71 / Replication protein A 14 kDa subunit / P35244* / replication protein A3*  / complex / reaction
 ENSMUSG00000027342 Pcna / P17918 / proliferating cell nuclear antigen / P12004*  / reaction / complex
 ENSMUSG00000035692 Isg15 / Q64339 / Ubiquitin-like protein ISG15 / P05161* / ISG15 ubiquitin-like modifier*  / reaction / complex
 ENSMUSG00000028884 Rpa2 / replication protein A2 / P15927*  / complex / reaction






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr