ENSMUSG00000025946


Mus musculus

Features
Gene ID: ENSMUSG00000025946
  
Biological name :Pth2r
  
Synonyms : Parathyroid hormone 2 receptor / Pth2r / Q91V95
  
Possible biological names infered from orthology : P49190
  
Species: Mus musculus
  
Chr. number: 1
Strand: 1
Band: C2
Gene start: 65282056
Gene end: 65389244
  
Corresponding Affymetrix probe sets: 10347018 (MoGene1.0st)   1452129_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000027083
Ensembl peptide - ENSMUSP00000114594
NCBI entrez gene - 213527     See in Manteia.
MGI - MGI:2180917
RefSeq - XM_017319688
RefSeq - NM_139270
RefSeq - XM_011238473
RefSeq - XM_011238474
RefSeq - XM_017319687
RefSeq - XM_006495842
RefSeq - XM_006495843
RefSeq Peptide - NP_644676
swissprot - Q91V95
swissprot - D3YV95
Ensembl - ENSMUSG00000025946
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pth2rENSDARG00000006678Danio rerio
 si:dkeyp-4h4.1ENSDARG00000021186Danio rerio
 PTH2RENSG00000144407Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Pth1r / P41593 / Parathyroid hormone/parathyroid hormone-related peptide receptor / Q03431* / parathyroid hormone 1 receptor*ENSMUSG0000003249247
Vipr1 / P97751 / vasoactive intestinal peptide receptor 1 / P32241*ENSMUSG0000003252830
Sctr / Q5FWI2 / Secretin receptor / P47872*ENSMUSG0000002638728
Vipr2 / P41588 / vasoactive intestinal peptide receptor 2 / P41587*ENSMUSG0000001117128
Glp1r / O35659 / Glucagon-like peptide 1 receptor / P43220*ENSMUSG0000002402727
Glp2r / Q5IXF8 / Glucagon-like peptide 2 receptor / O95838*ENSMUSG0000004992827
P70205 / Adcyap1r1 / adenylate cyclase activating polypeptide 1 receptor 1 / P41586* / ADCYAP receptor type I*ENSMUSG0000002977826
Gipr / Q0P543 / Gastric inhibitory polypeptide receptor / P48546*ENSMUSG0000003040625
Gcgr / Q61606 / Glucagon receptor / P47871*ENSMUSG0000002512725
Ghrhr / P32082 / Growth hormone-releasing hormone receptor / Q02643*ENSMUSG0000000465424


Protein motifs (from Interpro)
Interpro ID Name
 IPR000832  GPCR, family 2, secretin-like
 IPR001879  GPCR, family 2, extracellular hormone receptor domain
 IPR017981  GPCR, family 2-like
 IPR017983  GPCR, family 2, secretin-like, conserved site
 IPR036445  GPCR family 2, extracellular hormone receptor domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007166 cell surface receptor signaling pathway IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA


Pathways (from Reactome)
Pathway description
Class B/2 (Secretin family receptors)
G alpha (s) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000038300 Pth2 / Q91W27 / parathyroid hormone 2 / Q96A98*  / complex / reaction
 ENSMUSG00000048776 Pthlh / parathyroid hormone-like peptide / P12272* / parathyroid hormone like hormone*  / complex / reaction
 ENSMUSG00000059077 Pth / parathyroid hormone / P01270*  / reaction / complex






 

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