ENSMUSG00000030102


Mus musculus

Features
Gene ID: ENSMUSG00000030102
  
Biological name :Itpr1
  
Synonyms : Inositol 1,4,5-trisphosphate receptor type 1 / Itpr1 / P11881
  
Possible biological names infered from orthology : Q14643
  
Species: Mus musculus
  
Chr. number: 6
Strand: 1
Band: E1
Gene start: 108213096
Gene end: 108551109
  
Corresponding Affymetrix probe sets: 10540408 (MoGene1.0st)   1417279_at (Mouse Genome 430 2.0 Array)   1460203_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000145177
Ensembl peptide - ENSMUSP00000144880
Ensembl peptide - ENSMUSP00000145339
Ensembl peptide - ENSMUSP00000148284
Ensembl peptide - ENSMUSP00000145526
Ensembl peptide - ENSMUSP00000145522
Ensembl peptide - ENSMUSP00000032192
NCBI entrez gene - 16438     See in Manteia.
MGI - MGI:96623
RefSeq - XM_017321410
RefSeq - XM_006505632
RefSeq - XM_006505633
RefSeq - XM_006505636
RefSeq - XM_006505637
RefSeq - XM_017321407
RefSeq - XM_017321408
RefSeq - XM_017321409
RefSeq - NM_010585
RefSeq - XM_006505623
RefSeq - XM_006505624
RefSeq - XM_006505625
RefSeq - XM_006505626
RefSeq - XM_006505627
RefSeq - XM_006505628
RefSeq - XM_006505629
RefSeq - XM_006505630
RefSeq - XM_006505631
RefSeq Peptide - NP_034715
swissprot - A0A0N4SWI0
swissprot - A0A0N4SWH7
swissprot - A0A1D5RLA1
swissprot - A0A0N4SVN2
swissprot - P11881
swissprot - A0A0N4SW22
Ensembl - ENSMUSG00000030102
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 itpr1aENSDARG00000014655Danio rerio
 itpr1bENSDARG00000074149Danio rerio
 ITPR1ENSGALG00000008294Gallus gallus
 ITPR1ENSG00000150995Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Itpr2 / Q9Z329 / Inositol 1,4,5-trisphosphate receptor type 2 / Q14571*ENSMUSG0000003028768
Itpr3 / P70227 / Inositol 1,4,5-trisphosphate receptor type 3 / Q14573*ENSMUSG0000004264461
Ryr2 / E9Q401 / ryanodine receptor 2, cardiac / Q92736* / ryanodine receptor 2*ENSMUSG0000002131324
Ryr3 / A2AGL3 / Ryanodine receptor 3 / Q15413*ENSMUSG0000005737824
Ryr1 / E9PZQ0 / Ryanodine receptor 1 / P21817*ENSMUSG0000003059223


Protein motifs (from Interpro)
Interpro ID Name
 IPR000493  Inositol 1,4,5-trisphosphate receptor
 IPR000699  RIH domain
 IPR005821  Ion transport domain
 IPR013662  RyR/IP3R Homology associated domain
 IPR014821  Inositol 1,4,5-trisphosphate/ryanodine receptor
 IPR015925  Ryanodine receptor-related
 IPR016093  MIR motif
 IPR035910  RyR/IP3 receptor binding core, RIH domain superfamily
 IPR036300  Mir domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001666 response to hypoxia IDA
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006816 calcium ion transport IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0009791 post-embryonic development IMP
 biological_processGO:0032469 endoplasmic reticulum calcium ion homeostasis IGI
 biological_processGO:0042045 epithelial fluid transport IDA
 biological_processGO:0048016 inositol phosphate-mediated signaling IEA
 biological_processGO:0050849 negative regulation of calcium-mediated signaling ISO
 biological_processGO:0050882 voluntary musculoskeletal movement IMP
 biological_processGO:0051209 release of sequestered calcium ion into cytosol IMP
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0065009 regulation of molecular function IEA
 biological_processGO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress IMP
 biological_processGO:0070588 calcium ion transmembrane transport IEA
 cellular_componentGO:0005635 nuclear envelope IDA
 cellular_componentGO:0005637 nuclear inner membrane IDA
 cellular_componentGO:0005730 nucleolus IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IDA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0005955 calcineurin complex IDA
 cellular_componentGO:0014069 postsynaptic density IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016529 sarcoplasmic reticulum IDA
 cellular_componentGO:0030658 transport vesicle membrane IEA
 cellular_componentGO:0031088 platelet dense granule membrane ISO
 cellular_componentGO:0031094 platelet dense tubular network ISO
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity IEA
 molecular_functionGO:0005262 calcium channel activity IEA
 molecular_functionGO:0005509 calcium ion binding IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0015278 calcium-release channel activity IDA
 molecular_functionGO:0019855 calcium channel inhibitor activity ISO
 molecular_functionGO:0035091 phosphatidylinositol binding IDA
 molecular_functionGO:0070679 inositol 1,4,5 trisphosphate binding IEA


Pathways (from Reactome)
Pathway description
Effects of PIP2 hydrolysis
Elevation of cytosolic Ca2+ levels
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
cGMP effects
Ion homeostasis
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000746 weakness "state of being infirm or less strong than littermates" [J:45400]
Show

Allelic Composition: Sv2btm1Sud/Sv2btm1Sud
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0000774 reduced brain size "smaller appearance of the brain" [J:35802]
Show

Allelic Composition: Itpr1tm1Tno/Itpr1tm1Tno
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0000849 abnormal cerebellum morphology "any malformation or absence of the part of the metencephalon that lies in the posterior cranial fossa dorsal to the pons and medulla that is concerned with the coordination of movement and learning of motor skills" [J:50311, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]
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Allelic Composition: Itpr1tm1.1Kmik/Itpr1tm1.1Kmik,Tg(Pcp2-cre)2Mpin/0
Genetic Background: involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0000877 abnormal Purkinje cell "any structural anomaly of the neurons located at the interface of the molecular and internal granule layers of the cerebellar cortex; these inhibitory neurons provide the output of the cerebellar cortex through axons that project into the white matter, and extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells" [J:46140, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]
Show

Allelic Composition: Itpr1tm1.1Kmik/Itpr1tm1.1Kmik,Tg(Pcp2-cre)2Mpin/0
Genetic Background: involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0000890 thin cerebellar molecular layer "reduced width of the outer of the three cortical layers of the cerebellum" [J:46854]
Show

Allelic Composition: Itpr1tm1.1Kmik/Itpr1tm1.1Kmik,Tg(Pcp2-cre)2Mpin/0
Genetic Background: involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0001265 reduced body size "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]
Show

Allelic Composition: Sv2btm1Sud/Sv2btm1Sud
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0001322 abnormal iris morphology "structural anomaly of the adjustable membrane, composed of the stroma and pigmented epithelium, located just in front of the crystalline lens within the eye" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Mir301tm1Yoli/Mir301tm1Yoli
Genetic Background: involves: C57BL/6J

 MP:0001392 abnormal locomotor activity "altered ability or inability to move from place to place" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Sv2btm1Sud/Sv2btm1Sud
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0001393 ataxia "inability to coordinate voluntary muscular movements" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:67231]
Show

Allelic Composition: Itpr1tm1Tno/Itpr1tm1Tno
Genetic Background: involves: 129S4/SvJae * C57BL/6

Allelic Composition: Itpr1tm1.1Kmik/Itpr1tm1.1Kmik,Tg(Pcp2-cre)2Mpin/0
Genetic Background: involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0001405 impaired coordination "reduced ability to execute integrated movements of muscle" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Sv2btm1Sud/Sv2btm1Sud
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0001406 abnormal gait "unusual or distinctive way of walking" [J:65038]
Show

Allelic Composition: Drd2tm1Ebo/Drd2tm1Ebo
Genetic Background: B6.129S2-Drd2tm1Ebo

Allelic Composition: Glatm1Kul/Y,Itpr1wblo/Itpr1wblo
Genetic Background: B6;129-Glatm1Kul Itpr1wblo/GrsrJ

 MP:0001523 impaired righting response "reduced ability or greater amount of time needed to recover from supine position" [J:25565]
Show

Allelic Composition: Sv2btm1Sud/Sv2btm1Sud
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0001525 impaired balance "reduced ability of an animal to maintain equilibrium" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:64962, J:17123]
Show

Allelic Composition: Sv2btm1Sud/Sv2btm1Sud
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0001697 abnormal embryo size "anomalous proportions of embryo compared to littermates" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator]
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Allelic Composition: Grin2btm1e.1(KOMP)Wtsi/Grin2b+
Genetic Background: C57BL/6N-Grin2btm1e.1(KOMP)Wtsi/Tcp

Allelic Composition: Itpr1tm1.1(NCOM)Mfgc/Itpr1tm1.1(NCOM)Mfgc
Genetic Background: C57BL/6N-Itpr1tm1.1(NCOM)Mfgc/Tcp

 MP:0001899 absent long term depression "lack of the normal, persistent activity-dependent decrease in synaptic efficacy between neurons, often following slow, weak stimulation of CA1 neurons" [Principles of Neural Science:ISBN 0-8385-8034-3, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Itpr1tm1.1Kmik/Itpr1tm1.1Kmik,Tg(Pcp2-cre)2Mpin/0
Genetic Background: involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0002064 seizures "sudden and often acute manifestation of epileptic attack, sometimes convulsive" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Sv2btm1Sud/Sv2btm1Sud
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Itpr1tm1Tno/Itpr1tm1Tno
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Ambra1Gt(pGT1.8geo)1Fcec/Ambra1Gt(pGT1.8geo)1Fcec
Genetic Background: involves: CD-1 * NMRI

Allelic Composition: Itpr1m1Asb/Itpr1m1Asb
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0002206 abnormal CNS synaptic transmission "defect in the communication from a neuron to a target across a synapse in the central nervous system" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Itpr1tm1.1Kmik/Itpr1tm1.1Kmik,Tg(Pcp2-cre)2Mpin/0
Genetic Background: involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0002880 opisthotonus "a form of tetanic spasm in which the head, neck and spine are bent backward and the body is bowed forward" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Sv2btm1Sud/Sv2btm1Sud
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0002910 abnormal excitatory postsynaptic currents "defect in the size or duration of currents detected in postsynaptic cells when an excitatory impulse arrives at the synapse causing depolarization" [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]
Show

Allelic Composition: Itpr1tm1Tno/Itpr1tm1Tno
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0002912 abnormal excitatory postsynaptic potential "defect in the potential detected in postsynaptic cells when an excitatory impulse arrives at the synapse causing depolarization" [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]
Show

Allelic Composition: Itpr1tm1.1Kmik/Itpr1tm1.1Kmik,Tg(Pcp2-cre)2Mpin/0
Genetic Background: involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0003059 decreased insulin secretion "less than normal release of this hormone secreted by beta cells of the pancreas, that promotes glucose utilization, protein synthesis, and the formation and storage of neutral lipids " [MeSH:National Library of Medicine - Medical Subject Headings, 2003, RGD:Rat Genome Database submission]
Show

Allelic Composition: Ank2tm3.1Bnt/Ank2+
Genetic Background: B6.129(C)-Ank2tm3.1Bnt/J

 MP:0003232 abnormal forebrain development "anomaly in the formation or patterning of the anterior primitive cerebral vesicle; most rostral of three primary vesicles of the embryonic neural tube" [J:93081, smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Itpr1tm1.1(NCOM)Mfgc/Itpr1tm1.1(NCOM)Mfgc
Genetic Background: C57BL/6N-Itpr1tm1.1(NCOM)Mfgc/Tcp

 MP:0003312 abnormal locomotor coordination "reduced ability of an animal to maintain skillful and effective interaction of movements while engaging in locomotor activity" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Sv2btm1Sud/Sv2btm1Sud
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0003492 abnormal involuntary movement "anomalies in movements that occur independent of planning (eg. reflexive behavior)" [Nmice:Neuromice Consortium Submission]
Show

Allelic Composition: Ambra1Gt(pGT1.8geo)1Fcec/Ambra1Gt(pGT1.8geo)1Fcec
Genetic Background: involves: CD-1 * NMRI

Allelic Composition: Itpr1m1Asb/Itpr1m1Asb
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0003720 abnormal neural tube closure "abnormal invagination and fusion of the neuroepithelial layer in early development" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator, J:99099]
Show

Allelic Composition: Itpr1tm1.1(NCOM)Mfgc/Itpr1tm1.1(NCOM)Mfgc
Genetic Background: C57BL/6N-Itpr1tm1.1(NCOM)Mfgc/Tcp

 MP:0003864 abnormal midbrain development "anomaly in the formation of or the patterning of the part of the brainstem developing from the middle of the three primary cerebral vesicles of the embryo" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Itpr1tm1.1(NCOM)Mfgc/Itpr1tm1.1(NCOM)Mfgc
Genetic Background: C57BL/6N-Itpr1tm1.1(NCOM)Mfgc/Tcp

 MP:0003997 tonic-clonic seizures "increased number or decreased threshold for the induction of a seizure characterized by initial rigidity followed by rhythmic jerking movements" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Itpr1tm1Tno/Itpr1tm1Tno
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0004930 small epididymis "decrease in the average size of the elongated structure connected to the posterior surface of the testis that transports, stores, and matures spermatozoa between testis and vas deferens" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Grin2btm1e.1(KOMP)Wtsi/Grin2b+
Genetic Background: C57BL/6N-Grin2btm1e.1(KOMP)Wtsi/Tcp

 MP:0005012 decreased eosinophil count "fewer than normal eosinophil numbers " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Grin2btm1e.1(KOMP)Wtsi/Grin2b+
Genetic Background: C57BL/6N-Grin2btm1e.1(KOMP)Wtsi/Tcp

 MP:0005293 impaired glucose tolerance "less than the normal response to oral consumption or intravenous injection of specified amounts of glucose and indicative of insulin resistance; measured by determining whole blood or plasma sugar level in a fasting state before and after taking glucose at specified intervals" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Ank2tm3.1Bnt/Ank2+
Genetic Background: B6.129(C)-Ank2tm3.1Bnt/J

 MP:0005621 abnormal cell physiology "aberration in the vital processes of the cell " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, hdene:Howard Dene , Mouse Genome Informatics Curator]
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Allelic Composition: Sv2btm1Sud/Sv2btm1Sud
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0005635 decreased circulating bilirubin level "less thant the normal concentration in the blood of this yellow heme breakdown product" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, RGD:Rat Genome Database submission]
Show

Allelic Composition: Grin2btm1e.1(KOMP)Wtsi/Grin2b+
Genetic Background: C57BL/6N-Grin2btm1e.1(KOMP)Wtsi/Tcp

 MP:0006108 abnormal hindbrain development "anomaly in the formation or pattering of the caudal region of the brain" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:93573]
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Allelic Composition: Itpr1tm1.1(NCOM)Mfgc/Itpr1tm1.1(NCOM)Mfgc
Genetic Background: C57BL/6N-Itpr1tm1.1(NCOM)Mfgc/Tcp

 MP:0006156 abnormal visual pursuit "anomaly in the ability to selectively track a moving object" [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Itpr1tm1.1Kmik/Itpr1tm1.1Kmik,Tg(Pcp2-cre)2Mpin/0
Genetic Background: involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0008572 abnormal Purkinje cell dendrite morphology "any strucutral anomaly of the Purkinje cell body projections with hundreds of parallel spiny branches reaching up into the molecular layer" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Itpr1tm1.1Kmik/Itpr1tm1.1Kmik,Tg(Pcp2-cre)2Mpin/0
Genetic Background: involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6J

Allelic Composition: Itpr1tm1.1Kmik/Itpr1tm1.1Kmik,Tg(Pcp2-cre)2Mpin/0,Tg(Pcp2-EGFP)2Yuza/0
Genetic Background: involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N

 MP:0011083 complete lethality at weaning "premature death at weaning age of all organisms of a given genotype in a population, often due to the inability to make the transition to solid food" [MGI:csmith]
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Allelic Composition: Sv2btm1Sud/Sv2btm1Sud
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0011086 partial postnatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
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Allelic Composition: Itpr1tm1Tno/Itpr1tm1Tno
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0011101 partial prenatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith]
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Allelic Composition: Itpr1tm1Tno/Itpr1tm1Tno
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0013293 embryonic lethality prior to tooth bud stage "death prior to the appearance of tooth buds (Mus: E12-E12.5)" [MGI:smb]
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Allelic Composition: Itpr1tm1.1(NCOM)Mfgc/Itpr1tm1.1(NCOM)Mfgc
Genetic Background: C57BL/6N-Itpr1tm1.1(NCOM)Mfgc/Tcp

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000005611 Mrvi1 / Q9WUX5 / Protein MRVI1 / Q9Y6F6* / murine retrovirus integration site 1 homolog*  / complex
 ENSMUSG00000030987 Stim1 / P70302 / Stromal interaction molecule 1 / Q13586*  / reaction
 ENSMUSG00000027893 Ahcyl1 / Q80SW1 / Mus musculus S-adenosylhomocysteine hydrolase-like 1 (Ahcyl1), transcript variant 5, mRNA. / O43865* / adenosylhomocysteinase like 1*  / complex / reaction
 ENSMUSG00000030102 Itpr1 / P11881 / Inositol 1,4,5-trisphosphate receptor type 1 / Q14643*  / complex
 ENSMUSG00000029334 Prkg2 / protein kinase, cGMP-dependent, type II / Q13237*  / reaction
 ENSMUSG00000042644 Itpr3 / P70227 / Inositol 1,4,5-trisphosphate receptor type 3 / Q14573*  / complex
 ENSMUSG00000030287 Itpr2 / Q9Z329 / Inositol 1,4,5-trisphosphate receptor type 2 / Q14571*  / complex
 ENSMUSG00000052920 Prkg1 / P0C605 / protein kinase, cGMP-dependent, type I / Q13976*  / reaction






 

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