| MP:0000111 | cleft palate | "congenital fissure of the tissues normally uniting to form the palate" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840] |
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Allelic Composition: Rdh10tm1c(KOMP)Wtsi/Rdh10tm1c(KOMP)Wtsi,Tg(Amh-cre)8815Reb/0,Tg(RARE-Hspa1b/lacZ)12Jrt/0,Tg(Stra8-icre)1Reb/0
Genetic Background: involves: C57BL/6 * C57BL/6N * CD-1 * FVB/N * SJL
Allelic Composition: Plxnd1b2b3150Clo/Plxnd1b2b3150Clo
Genetic Background: C57BL/6J-Plxnd1b2b3150Clo
|
| MP:0000141 | abnormal vertebral body morphology | "malformed main portion of the vertebra anterior to the vertebral canal" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:55583] |
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Allelic Composition: Cenpetm1Dwc/Cenpetm2Dwc
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Plxnd1tm1Joe/Plxnd1tm1Joe
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
|
| MP:0000154 | rib fusion | "appearance of one or more ribs as a single structure" [J:62022, J:62023] |
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Allelic Composition: Cenpetm1Dwc/Cenpetm2Dwc
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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| MP:0000272 | abnormal aorta morphology | "structural anomaly of the main trunk of the systemic arteries" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Cenpetm1Dwc/Cenpetm2Dwc
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
| MP:0000284 | double outlet right ventricle | "both the aorta and the pulmonary trunk originate from the right ventricle, usually in conjunction with a ventricular septal defect" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:67826] |
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Allelic Composition: Ccdc39b2b1304Clo/Ccdc39b2b1304Clo
Genetic Background: C57BL/6J-Ccdc39b2b1304Clo
Allelic Composition: Plxnd1b2b1863Clo/Plxnd1b2b1863Clo
Genetic Background: C57BL/6J-Plxnd1b2b1863Clo
|
| MP:0000445 | short snout | "reduced length of the anterior facial part of the muzzle" [J:53370] |
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Allelic Composition: Plxnd1b2b3150Clo/Plxnd1b2b3150Clo
Genetic Background: C57BL/6J-Plxnd1b2b3150Clo
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| MP:0000520 | absent kidney | "missing paired organs that excrete urine" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49471] |
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Allelic Composition: Ccdc39b2b1304Clo/Ccdc39b2b1304Clo
Genetic Background: C57BL/6J-Ccdc39b2b1304Clo
Allelic Composition: Plxnd1b2b1863Clo/Plxnd1b2b1863Clo
Genetic Background: C57BL/6J-Plxnd1b2b1863Clo
Allelic Composition: Plxnd1b2b3150Clo/Plxnd1b2b3150Clo
Genetic Background: C57BL/6J-Plxnd1b2b3150Clo
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| MP:0000592 | short tail | "reduced length of tail compared to control " [J:55583] |
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Allelic Composition: Cenpetm1Dwc/Cenpetm2Dwc
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
| MP:0000937 | abnormal motor neuron morphology | "malformation or absence of cells that innervate an effector (muscle or glandular) tissue; responsible for transmission of motor impulses" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:60159] |
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Allelic Composition: Rasgrf1tm1Toc/Rasgrf1tm1Toc
Genetic Background: involves: 129/Sv
|
| MP:0000940 | abnormal motor neuron innervation | "misprojection or failure to bundle motor axons to an effector tissue" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:60159] |
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Allelic Composition: Rasgrf1tm1Toc/Rasgrf1tm1Toc
Genetic Background: involves: 129/Sv
|
| MP:0001255 | decreased body height | "decreased shoulder to floor distance compared to controls" [dlb:Donna Burkart, Mouse Genome Informatics Curator] |
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Allelic Composition: Cenpetm1Dwc/Cenpetm2Dwc
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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| MP:0001575 | cyanosis | "a dark bluish or purple skin discoloration resulting from deficient oxygenation of the blood" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60159] |
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Allelic Composition: Cux1tm1Mbu/Cux1tm1Mbu
Genetic Background: involves: OF1
Allelic Composition: Plxnd1tm1.1Tmj/Plxnd1tm1.1Tmj,Tg(Tek-cre)1Ywa/0
Genetic Background: involves: 129S/SvEv * 129S4/SvJaeSor * C57BL/6 * SJL
|
| MP:0001614 | abnormal vasculature | "anomalies in the structure of development of the network of tubes that carries blood through the body" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Cenpetm1Dwc/Cenpetm2Dwc
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
| MP:0001823 | thymus hypoplasia | "small size due to reduced cell number in the thymus" [J:23255] |
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Allelic Composition: Rdh10tm1c(KOMP)Wtsi/Rdh10tm1c(KOMP)Wtsi,Tg(Amh-cre)8815Reb/0,Tg(RARE-Hspa1b/lacZ)12Jrt/0,Tg(Stra8-icre)1Reb/0
Genetic Background: involves: C57BL/6 * C57BL/6N * CD-1 * FVB/N * SJL
Allelic Composition: Plxnd1b2b3150Clo/Plxnd1b2b3150Clo
Genetic Background: C57BL/6J-Plxnd1b2b3150Clo
|
| MP:0001914 | hemorrhage | "loss of blood from the vascular compartment to the exterior or into nonvascular body space as a result of rupture or severance of the blood vessels" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Plxnd1tm1.1Tmj/Plxnd1tm1.1Tmj,Tg(Tek-cre)1Ywa/0
Genetic Background: involves: 129S/SvEv * 129S4/SvJaeSor * C57BL/6 * SJL
Allelic Composition: Plxnd1tm1.1Tmj/Plxnd1tm1.1Tmj,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129S/SvEv * 129S4/SvJaeSor * C57BL/6 * CBA
|
| MP:0001915 | intracranial hemorrhage | "bleeding within the skull, including hemorrhage into the brain and within the cranial epidural, subdural, and subarachnoid spaces" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Plxnd1tm1.1Tmj/Plxnd1tm1.1Tmj,Tg(Tek-cre)1Ywa/0
Genetic Background: involves: 129S/SvEv * 129S4/SvJaeSor * C57BL/6 * SJL
|
| MP:0002169 | no phenotype detected | "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Adgra2tm1.1Vlcg/Adgra2tm2.1Vlcg,Gt(ROSA)26Sortm3.1(cre/ERT2)Vlcg/Gt(ROSA)26Sor+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6NTac
|
| MP:0002191 | abnormal artery morphology | "malformation of the blood vessels that carry blood away from the heart" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Cux1tm1Mbu/Cux1tm1Mbu
Genetic Background: involves: OF1
|
| MP:0002633 | persistent truncus arteriosis | "complete failure of the common arterial trunk opening out of both ventricles to divide into the aorta and pulmonary artery during development" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Cux1tm1Mbu/Cux1tm1Mbu
Genetic Background: involves: OF1
Allelic Composition: Plxnd1tm1.1Tmj/Plxnd1tm1.1Tmj,Tg(Tek-cre)1Ywa/0
Genetic Background: involves: 129S/SvEv * 129S4/SvJaeSor * C57BL/6 * SJL
Allelic Composition: Plxnd1b2b553Clo/Plxnd1b2b553Clo
Genetic Background: C57BL/6J-Plxnd1b2b553Clo
Allelic Composition: Plxnd1b2b3150Clo/Plxnd1b2b3150Clo
Genetic Background: C57BL/6J-Plxnd1b2b3150Clo
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| MP:0002639 | micrognathia | "abnormally reduced size of the jaws, especially of the mandible" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
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Allelic Composition: Plxnd1b2b3150Clo/Plxnd1b2b3150Clo
Genetic Background: C57BL/6J-Plxnd1b2b3150Clo
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| MP:0002792 | abnormal retinal vascularization | "malformation or disorganization of the blood vessels supplying the retina" [cml:Cathleen M. Lutz , Mouse Genome Informatics Curator] |
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Allelic Composition: Plxnd1tm1.1Tmj/Plxnd1tm1.1Tmj,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129S/SvEv * 129S4/SvJaeSor * C57BL/6 * CBA
|
| MP:0002912 | abnormal excitatory postsynaptic potential | "defect in the potential detected in postsynaptic cells when an excitatory impulse arrives at the synapse causing depolarization" [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3] |
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Allelic Composition: Mapttm1(Sema3e)Yuyo/Mapt+,Olig2tm1(cre)Tmj/Olig2+
Genetic Background: Not Specified
|
| MP:0003057 | abnormal epicardium morphology | "anomalous structure of the visceral layer of the pericardium that surrounds and attaches to all the surfaces of the heart" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8, ava:Anna V. Anagnostopoulos, Mouse Genome Informatics Curator] |
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Allelic Composition: Plxnd1tm1.1Tmj/Plxnd1tm1.1Tmj,Tg(Tek-cre)1Ywa/0
Genetic Background: involves: 129S/SvEv * 129S4/SvJaeSor * C57BL/6 * SJL
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| MP:0003105 | abnormal heart atrium morphology | "structural anomaly of one or both of the two upper chambers of the heart " [csmith:Cynthia L. Smith, Mouse Genome Informatics Curator] |
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Allelic Composition: Cux1tm1Mbu/Cux1tm1Mbu
Genetic Background: involves: OF1
Allelic Composition: Plxnd1tm1.1Tmj/Plxnd1tm1.1Tmj,Tg(Tek-cre)1Ywa/0
Genetic Background: involves: 129S/SvEv * 129S4/SvJaeSor * C57BL/6 * SJL
|
| MP:0003140 | dilated atria | "an expansion in the volume of one or both of the upper chambers of the heart" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Plxnd1tm1.1Tmj/Plxnd1tm1.1Tmj,Tg(Tek-cre)1Ywa/0
Genetic Background: involves: 129S/SvEv * 129S4/SvJaeSor * C57BL/6 * SJL
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| MP:0003544 | abnormal vascular endothelial cell migration | "anomaly in the movement of endothelial cell or their precursors to the appropriate location in the body" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:95387] |
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Allelic Composition: Plxnd1tm1Joe/Plxnd1tm1Joe
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Plxnd1tm1.1Tmj/Plxnd1tm1.1Tmj,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129S/SvEv * 129S4/SvJaeSor * C57BL/6 * CBA
|
| MP:0004158 | right aortic arch | "the aortic arch lies to the right of the trachea and esophagus; results from persistance of the entire right dorsal arch and involution of a segment of the left arch" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator] |
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Allelic Composition: Cux1tm1Mbu/Cux1tm1Mbu
Genetic Background: involves: OF1
Allelic Composition: Plxnd1tm1.1Tmj/Plxnd1tm1.1Tmj,Tg(Tek-cre)1Ywa/0
Genetic Background: involves: 129S/SvEv * 129S4/SvJaeSor * C57BL/6 * SJL
Allelic Composition: Plxnd1b2b553Clo/Plxnd1b2b553Clo
Genetic Background: C57BL/6J-Plxnd1b2b553Clo
Allelic Composition: Plxnd1b2b1863Clo/Plxnd1b2b1863Clo
Genetic Background: C57BL/6J-Plxnd1b2b1863Clo
Allelic Composition: Plxnd1b2b3150Clo/Plxnd1b2b3150Clo
Genetic Background: C57BL/6J-Plxnd1b2b3150Clo
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| MP:0004612 | fusion of vertebral bodies | "improper union of the main cylindrical portion of adjacent vertebra ventral to the vertebral canal" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Plxnd1tm1.1Tmj/Plxnd1tm1.1Tmj,Tg(Tek-cre)1Ywa/0
Genetic Background: involves: 129S/SvEv * 129S4/SvJaeSor * C57BL/6 * SJL
Allelic Composition: Plxnd1tm1Joe/Plxnd1tm1Joe
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
|
| MP:0005329 | abnormal cardiac muscle morphology | "anomalous structure of the involuntary muscle comprising the myocardium " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
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Allelic Composition: Plxnd1tm1.1Tmj/Plxnd1tm1.1Tmj,Tg(Tek-cre)1Ywa/0
Genetic Background: involves: 129S/SvEv * 129S4/SvJaeSor * C57BL/6 * SJL
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| MP:0005592 | abnormal vascular smooth muscle morphology | "structural anomaly of the nonstriated, involuntary muscle tissue of the blood vessels" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Cux1tm1Mbu/Cux1tm1Mbu
Genetic Background: involves: OF1
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| MP:0005601 | increased angiogenesis | "enhanced process of blood vessel formation and the subsequent remodeling process; does not refer to the initial establishment of the vascular network" [RGD:Rat Genome Database submission] |
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Allelic Composition: Cux1tm1Mbu/Cux1tm1Mbu
Genetic Background: involves: OF1
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| MP:0005602 | decreased angiogenesis | "reduced process of blood vessel formation and the subsequent remodeling process; does not refer to the initial establishment of the vascular network" [RGD:Rat Genome Database submission] |
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Allelic Composition: Plxnd1tm1.1Tmj/Plxnd1tm1.1Tmj,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129S/SvEv * 129S4/SvJaeSor * C57BL/6 * CBA
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| MP:0006063 | abnormal inferior vena cava morphology | "structural malformation in the principal vein draining blood from the lower portion of the body" [smb:Susan M Bello, Mouse Genome Informatics Curator, Taber s Cyclopedic Medical Dictionary:19th edition: ISBN N 0-8036-0655-99] |
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Allelic Composition: Plxnd1b2b553Clo/Plxnd1b2b553Clo
Genetic Background: C57BL/6J-Plxnd1b2b553Clo
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| MP:0006354 | abnormal fourth branchial arch artery morphology | "any structural anomaly of the vessels formed within the fourth pair of branchial arches in embryogenesis" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Cux1tm1Mbu/Cux1tm1Mbu
Genetic Background: involves: OF1
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| MP:0006355 | abnormal sixth branchial arch artery morphology | "any structural anomaly of the vessels formed within the sixth pair of branchial arches in embryogenesis" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Cux1tm1Mbu/Cux1tm1Mbu
Genetic Background: involves: OF1
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| MP:0008725 | enlarged heart atrium | "increased size of one or both of the two upper chambers of the heart, to which the blood returns from the circulation" [MESH:A07.541.358] |
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Allelic Composition: Cux1tm1Mbu/Cux1tm1Mbu
Genetic Background: involves: OF1
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| MP:0009660 | abnormal induced retinal neovascularization | "any anomaly in the response to conditions which induce the pathological growth of vessels into the retina" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Gt(ROSA)26Sortm1(CAG-Rhoj,-EGFP)Auem/Gt(ROSA)26Sortm1(CAG-Rhoj,-EGFP)Auem,Tg(Tek-cre)#Rwng/0
Genetic Background: involves: C57BL/6 * CBA
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| MP:0010402 | ventricular septal defect | "abnormal communications between the two lower chambers of the heart, including such defects in the perimembranous, inlet, outlet (infundibular), central muscular, marginal muscular, or apical muscular regions" [MESH:C14.240.400.560.540] |
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Allelic Composition: Plxnd1tm1.1Tmj/Plxnd1tm1.1Tmj,Tg(Tek-cre)1Ywa/0
Genetic Background: involves: 129S/SvEv * 129S4/SvJaeSor * C57BL/6 * SJL
Allelic Composition: Plxnd1b2b3150Clo/Plxnd1b2b3150Clo
Genetic Background: C57BL/6J-Plxnd1b2b3150Clo
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| MP:0010406 | absent atrial septum | "absence of the thin membranous structure between the two heart atria" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Plxnd1b2b3150Clo/Plxnd1b2b3150Clo
Genetic Background: C57BL/6J-Plxnd1b2b3150Clo
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| MP:0010412 | atrioventricular septal defect | "defects in the thin membranous structure between the right atrium and left ventricle that arise from faulty development of the embryonic endocardial cushions; the spectrum ranges from a primum atrial septal defect and cleft mitral valve, known as a partial atrioventricular septal defect (partial AVSD), to defects of both the primum atrial septum and inlet ventricular septum and the presence of a common atrioventricular valve, referred to as complete atrioventricular septal defect (complete AVSD)" [http://emedicine.medscape.com] |
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Allelic Composition: Plxnd1b2b1863Clo/Plxnd1b2b1863Clo
Genetic Background: C57BL/6J-Plxnd1b2b1863Clo
Allelic Composition: Plxnd1b2b3150Clo/Plxnd1b2b3150Clo
Genetic Background: C57BL/6J-Plxnd1b2b3150Clo
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| MP:0010413 | complete atrioventricular septal defect | "a type of atrioventricular septal defect in which a single atrioventricular valve annulus, a common atrioventricular valve, and a defect of the inlet ventricular septum are observed; deficiency of the atrioventricular septum also results in the presence of a large primum atrial septal defect" [http://emedicine.medscape.com] |
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Allelic Composition: Plxnd1b2b553Clo/Plxnd1b2b553Clo
Genetic Background: C57BL/6J-Plxnd1b2b553Clo
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| MP:0010454 | abnormal truncus arteriosis septation | "anomaly in the process of dividing the common arterial trunk arising out of both heart ventricles to divide into the aorta and pulmonary artery during development" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Plxnd1tm1.1Tmj/Plxnd1tm1.1Tmj,Tg(Tek-cre)1Ywa/0
Genetic Background: involves: 129S/SvEv * 129S4/SvJaeSor * C57BL/6 * SJL
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| MP:0010465 | aberrant origin of the right subclavian artery | "the right subclavian artery arises from an atypical location on the aortic arch or the proximal descending aorta" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Cux1tm1Mbu/Cux1tm1Mbu
Genetic Background: involves: OF1
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| MP:0010466 | vascular ring | "the trachea and esophagus are completely encircled by connected segments of the aortic arch and its branches" [http://emedicine.medscape.com] |
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Allelic Composition: Plxnd1b2b3150Clo/Plxnd1b2b3150Clo
Genetic Background: C57BL/6J-Plxnd1b2b3150Clo
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| MP:0010472 | abnormal ascending aorta and coronary artery attachment | "any anomaly of the connection site of any or all of the coronary arteries to the ascending aorta" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Cux1tm1Mbu/Cux1tm1Mbu
Genetic Background: involves: OF1
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| MP:0010488 | abnormal left subclavian artery morphology | "any structural anomaly of the artery that extends from the aortic arch to the left side of the body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Cux1tm1Mbu/Cux1tm1Mbu
Genetic Background: involves: OF1
Allelic Composition: Plxnd1b2b3150Clo/Plxnd1b2b3150Clo
Genetic Background: C57BL/6J-Plxnd1b2b3150Clo
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| MP:0010551 | abnormal coronary vessel morphology | "any structural anomaly of any of the arteries or veins that supply blood to the heart or return blood from the heart muscles to the circulation" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Plxnd1tm1.1Tmj/Plxnd1tm1.1Tmj,Tg(Tek-cre)1Ywa/0
Genetic Background: involves: 129S/SvEv * 129S4/SvJaeSor * C57BL/6 * SJL
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| MP:0010565 | absent fetal ductus arteriosus | "absence of the fetal vessel that connects the left pulmonary artery with the descending aorta" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Cux1tm1Mbu/Cux1tm1Mbu
Genetic Background: involves: OF1
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| MP:0011085 | complete postnatal lethality | "premature death anytime between the neonatal period and weaning age of all organisms of a given genotype in a population (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith] |
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Allelic Composition: Plxnd1tm1.1Tmj/Plxnd1tm1.1Tmj,Tg(Tek-cre)1Ywa/0
Genetic Background: involves: 129S/SvEv * 129S4/SvJaeSor * C57BL/6 * SJL
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| MP:0011087 | complete neonatal lethality | "death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith] |
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Allelic Composition: Cux1tm1Mbu/Cux1tm1Mbu
Genetic Background: involves: OF1
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| MP:0011088 | partial neonatal lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the neonatal period after birth (Mus: P0)" [MGI:csmith] |
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Allelic Composition: Plxnd1tm1.1Tmj/Plxnd1tm1.1Tmj,Tg(Tek-cre)1Ywa/0
Genetic Background: involves: 129S/SvEv * 129S4/SvJaeSor * C57BL/6 * SJL
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| MP:0011661 | persistent truncus arteriosus type i | "complete failure of the common arterial trunk opening out of both ventricles to divide into the aorta and pulmonary artery during development; type i is characterized by origin of a single pulmonary trunk from the left lateral aspect of the common trunk, with branching of the left and right pulmonary arteries from the pulmonary trunk" [http://emedicine.medscape.com] |
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Allelic Composition: Plxnd1b2b553Clo/Plxnd1b2b553Clo
Genetic Background: C57BL/6J-Plxnd1b2b553Clo
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| MP:0011662 | persistent truncus arteriosus type ii | "complete failure of the common arterial trunk opening out of both ventricles to divide into the aorta and pulmonary artery during development; type II is characterized by separate but proximate origins of the left and right pulmonary arterial branches from the posterolateral aspect of the common arterial trunk" [http://emedicine.medscape.com] |
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Allelic Composition: Plxnd1b2b553Clo/Plxnd1b2b553Clo
Genetic Background: C57BL/6J-Plxnd1b2b553Clo
Allelic Composition: Plxnd1b2b1863Clo/Plxnd1b2b1863Clo
Genetic Background: C57BL/6J-Plxnd1b2b1863Clo
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| MP:0011681 | atrium cysts | "abnormal membranous sacs in any portion of the paired upper chambers of the heart" [MGI:csmith] |
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Allelic Composition: Plxnd1b2b553Clo/Plxnd1b2b553Clo
Genetic Background: C57BL/6J-Plxnd1b2b553Clo
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| MP:0011682 | renal glomerulus cysts | "abnormal membranous sacs in any portion of the renal glomerulus" [MGI:csmith] |
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Allelic Composition: Plxnd1b2b553Clo/Plxnd1b2b553Clo
Genetic Background: C57BL/6J-Plxnd1b2b553Clo
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| MP:0011683 | dual inferior vena cava | "presence of two inferior vena cavae, often resulting from the persistence of both supracardinal veins during development; the two structures may be symmetric or asymmetric but typically join together at the renal vein" [MGI:csmith, PMID:10835118] |
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Allelic Composition: Plxnd1b2b553Clo/Plxnd1b2b553Clo
Genetic Background: C57BL/6J-Plxnd1b2b553Clo
Allelic Composition: Plxnd1b2b1863Clo/Plxnd1b2b1863Clo
Genetic Background: C57BL/6J-Plxnd1b2b1863Clo
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| MP:0012253 | abnormal intersomitic vessel morphology | "any structural anomaly of the primary blood vessel sprouts that originate from the dorsal aorta and posterior cardinal vein and align dorsoventrally at the myotomal boundaries between somites" [MGI:anna] |
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Allelic Composition: Cux1tm1Mbu/Cux1tm1Mbu
Genetic Background: involves: OF1
Allelic Composition: Plxnd1tm1Ddg/Plxnd1tm1Ddg
Genetic Background: involves: 129S/SvEv * C57BL/6J
Allelic Composition: Plxnd1tm1.1Tmj/Plxnd1tm1.1Tmj,Tg(Tek-cre)1Ywa/0
Genetic Background: involves: 129S/SvEv * 129S4/SvJaeSor * C57BL/6 * SJL
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