ENSMUSG00000031026


Mus musculus

Features
Gene ID: ENSMUSG00000031026
  
Biological name :Trim66
  
Synonyms : Q924W6 / Trim66 / tripartite motif-containing 66
  
Possible biological names infered from orthology : O15016
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: E3
Gene start: 109449006
Gene end: 109508134
  
Corresponding Affymetrix probe sets: 10566743 (MoGene1.0st)   1456967_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000102352
Ensembl peptide - ENSMUSP00000033339
Ensembl peptide - ENSMUSP00000102350
NCBI entrez gene - 330627     See in Manteia.
MGI - MGI:2152406
RefSeq - XM_011241835
RefSeq - NM_001170913
RefSeq - NM_181853
RefSeq - XM_006507959
RefSeq - XM_006507960
RefSeq - XM_006507961
RefSeq - XM_006507962
RefSeq - NM_001170912
RefSeq Peptide - NP_862901
RefSeq Peptide - NP_001164383
RefSeq Peptide - NP_001164384
swissprot - E9QLR8
swissprot - Q924W6
swissprot - E9PZP2
Ensembl - ENSMUSG00000031026
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 trim66ENSDARG00000054332Danio rerio
 TRIM66ENSGALG00000005958Gallus gallus
 O15016ENSG00000166436Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Trim33 / tripartite motif containing 33 / Q9UPN9*ENSMUSG0000003301424
Q64127 / Trim24 / Transcription intermediary factor 1-alpha / O15164* / tripartite motif containing 24*ENSMUSG0000002983323
Q62318 / Trim28 / tripartite motif-containing 28 / Q13263*ENSMUSG0000000556614
Q1PSW8 / Trim71 / tripartite motif-containing 71 / Q2Q1W2*ENSMUSG000000792599
Trim3 / Q9R1R2 / tripartite motif-containing 3 / O75382*ENSMUSG000000369898
Trim2 / Q9ESN6 / tripartite motif-containing 2 / Q9C040*ENSMUSG000000279938
Q6PFY8 / Trim45 / Tripartite motif-containing protein 45 / Q9H8W5* / tripartite motif containing 45*ENSMUSG000000332338
Trim56 / tripartite motif containing 56 / Q9BRZ2*ENSMUSG000000432797


Protein motifs (from Interpro)
Interpro ID Name
 IPR000315  B-box-type zinc finger
 IPR001487  Bromodomain
 IPR001841  Zinc finger, RING-type
 IPR001965  Zinc finger, PHD-type
 IPR003649  B-box, C-terminal
 IPR011011  Zinc finger, FYVE/PHD-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR017907  Zinc finger, RING-type, conserved site
 IPR019786  Zinc finger, PHD-type, conserved site
 IPR019787  Zinc finger, PHD-finger
 IPR036427  Bromodomain-like superfamily
 IPR037372  Tripartite motif-containing protein 66


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IDA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm ISO
 cellular_componentGO:0010369 chromocenter IDA
 cellular_componentGO:0016235 aggresome ISO
 molecular_functionGO:0003682 chromatin binding IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
Show

Allelic Composition: Kmt5btm1a(KOMP)Wtsi/Kmt5btm1a(KOMP)Wtsi
Genetic Background: B6JTyr;B6N-Kmt5btm1a(KOMP)Wtsi/Wtsi

 MP:0001415 increased exploration in new environment "greater amount of time spent investigating new location" [J:28825]
Show

Allelic Composition: Kmt5btm1a(KOMP)Wtsi/Kmt5btm1a(KOMP)Wtsi
Genetic Background: B6JTyr;B6N-Kmt5btm1a(KOMP)Wtsi/Wtsi

 MP:0005561 increased mean corpuscular hemoglobin "greater than the average levels of hemoglobin contained in an erythrocyte" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Kmt5btm1a(KOMP)Wtsi/Kmt5btm1a(KOMP)Wtsi
Genetic Background: B6JTyr;B6N-Kmt5btm1a(KOMP)Wtsi/Wtsi

 MP:0010025 decreased total body fat amount "less than the normal total amount of connective tissue composed of fat cells within the entire body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Kmt5btm1a(KOMP)Wtsi/Kmt5btm1a(KOMP)Wtsi
Genetic Background: B6JTyr;B6N-Kmt5btm1a(KOMP)Wtsi/Wtsi

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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