ENSMUSG00000043279


Mus musculus

Features
Gene ID: ENSMUSG00000043279
  
Biological name :Trim56
  
Synonyms : Trim56 / tripartite motif containing 56
  
Possible biological names infered from orthology : Q9BRZ2
  
Species: Mus musculus
  
Chr. number: 5
Strand: -1
Band: G2
Gene start: 137105644
Gene end: 137116209
  
Corresponding Affymetrix probe sets: 10534679 (MoGene1.0st)   1441320_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000058109
Ensembl peptide - ENSMUSP00000117874
NCBI entrez gene - 384309     See in Manteia.
MGI - MGI:2685298
RefSeq - NM_201373
RefSeq - XM_006504441
RefSeq - XM_011240883
RefSeq Peptide - NP_958761
swissprot - D3YVX5
swissprot - A0A0R4J0Q6
Ensembl - ENSMUSG00000043279
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q9BRZ2ENSG00000169871Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Trim2 / Q9ESN6 / tripartite motif-containing 2 / Q9C040*ENSMUSG0000002799318
Q6PFY8 / Trim45 / Tripartite motif-containing protein 45 / Q9H8W5* / tripartite motif containing 45*ENSMUSG0000003323318
Trim3 / Q9R1R2 / tripartite motif-containing 3 / O75382*ENSMUSG0000003698917
Q1PSW8 / Trim71 / tripartite motif-containing 71 / Q2Q1W2*ENSMUSG0000007925916
Trim33 / tripartite motif containing 33 / Q9UPN9*ENSMUSG0000003301415
Q924W6 / Trim66 / tripartite motif-containing 66 / O15016*ENSMUSG0000003102613
Q64127 / Trim24 / Transcription intermediary factor 1-alpha / O15164* / tripartite motif containing 24*ENSMUSG0000002983313
Q62318 / Trim28 / tripartite motif-containing 28 / Q13263*ENSMUSG0000000556613


Protein motifs (from Interpro)
Interpro ID Name
 IPR000315  B-box-type zinc finger
 IPR001841  Zinc finger, RING-type
 IPR011042  Six-bladed beta-propeller, TolB-like
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR017907  Zinc finger, RING-type, conserved site
 IPR027370  RING-type zinc-finger, LisH dimerisation motif


Gene Ontology (GO)
TypeGO IDTermEv.Code
 cellular_componentGO:0005622 intracellular IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Regulation of innate immune responses to cytosolic DNA


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0008079 decreased CD8-positive T cell number "reduction in the number of the regulatory subset of T lymphocytes that are involved in MHC class I restricted interactions" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Tmem79tm1.1(KOMP)Wtsi/Tmem79tm1.1(KOMP)Wtsi
Genetic Background: C57BL/6N-Tmem79tm1.1(KOMP)Wtsi/J

 MP:0010169 decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number "a reduction in the number of the CD4-positive, CD25-positive T cell subset which regulates overall immune responses as well as the responses of other T cell subsets through direct cell-cell contact and cytokine release" [ISBN:0781735149]
Show

Allelic Composition: Tmem79tm1.1(KOMP)Wtsi/Tmem79tm1.1(KOMP)Wtsi
Genetic Background: C57BL/6N-Tmem79tm1.1(KOMP)Wtsi/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000024349 Q3TBT3 / Tmem173 / Stimulator of interferons protein / Q86WV6* / transmembrane protein 173*  / reaction / complex






 

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