ENSMUSG00000036989


Mus musculus

Features
Gene ID: ENSMUSG00000036989
  
Biological name :Trim3
  
Synonyms : Q9R1R2 / Trim3 / tripartite motif-containing 3
  
Possible biological names infered from orthology : O75382
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: E3
Gene start: 105604463
Gene end: 105633571
  
Corresponding Affymetrix probe sets: 10566488 (MoGene1.0st)   1451663_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000053384
Ensembl peptide - ENSMUSP00000102403
Ensembl peptide - ENSMUSP00000114822
Ensembl peptide - ENSMUSP00000119910
Ensembl peptide - ENSMUSP00000102401
NCBI entrez gene - 55992     See in Manteia.
MGI - MGI:1860040
RefSeq - XM_006508041
RefSeq - NM_001285870
RefSeq - NM_001285871
RefSeq - NM_001285873
RefSeq - NM_018880
RefSeq - XM_006508037
RefSeq - XM_006508038
RefSeq - XM_006508039
RefSeq - XM_006508040
RefSeq Peptide - NP_061368
RefSeq Peptide - NP_001272799
RefSeq Peptide - NP_001272800
RefSeq Peptide - NP_001272802
swissprot - D3YUY7
swissprot - Q3TDT0
swissprot - Q9R1R2
swissprot - D3Z7V9
Ensembl - ENSMUSG00000036989
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 trim3aENSDARG00000063711Danio rerio
 trim3bENSDARG00000005397Danio rerio
 TRIM3ENSGALG00000034004Gallus gallus
 TRIM3ENSG00000110171Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Trim2 / Q9ESN6 / tripartite motif-containing 2 / Q9C040*ENSMUSG0000002799367
Q1PSW8 / Trim71 / tripartite motif-containing 71 / Q2Q1W2*ENSMUSG0000007925932
Q6PFY8 / Trim45 / Tripartite motif-containing protein 45 / Q9H8W5* / tripartite motif containing 45*ENSMUSG0000003323319
Trim56 / tripartite motif containing 56 / Q9BRZ2*ENSMUSG0000004327917
Trim33 / tripartite motif containing 33 / Q9UPN9*ENSMUSG0000003301417
Q64127 / Trim24 / Transcription intermediary factor 1-alpha / O15164* / tripartite motif containing 24*ENSMUSG0000002983316
Q62318 / Trim28 / tripartite motif-containing 28 / Q13263*ENSMUSG0000000556614
Q924W6 / Trim66 / tripartite motif-containing 66 / O15016*ENSMUSG0000003102614


Protein motifs (from Interpro)
Interpro ID Name
 IPR000315  B-box-type zinc finger
 IPR001258  NHL repeat
 IPR001298  Filamin/ABP280 repeat
 IPR001841  Zinc finger, RING-type
 IPR003649  B-box, C-terminal
 IPR011042  Six-bladed beta-propeller, TolB-like
 IPR013017  NHL repeat, subgroup
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013783  Immunoglobulin-like fold
 IPR014756  Immunoglobulin E-set
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017868  Filamin/ABP280 repeat-like
 IPR017907  Zinc finger, RING-type, conserved site
 IPR027370  RING-type zinc-finger, LisH dimerisation motif


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016567 protein ubiquitination IDA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005769 early endosome IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Jak2m1Dlbr/Jak2tm1Jni
Genetic Background: involves: 129P2/OlaHsd * 129S1/SvImJ * C57BL/6J

 MP:0002887 resistance to pharmacologically induced seizures "ability to withstand doses of pharmacological drugs that induce seizure activity in normal animals" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:77284]
Show

Allelic Composition: Timd4tm1Kuch/Timd4tm1Kuch
Genetic Background: C57BL/6-Timd4tm1Kuch

 MP:0009435 abnormal miniature inhibitory postsynaptic currents "defect in the size or duration of spontaneous currents detected in postsynaptic cells that occur in the absence of an inhibitory impulse" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Timd4tm1Kuch/Timd4tm1Kuch
Genetic Background: C57BL/6-Timd4tm1Kuch

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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