ENSMUSG00000036655


Mus musculus

Features
Gene ID: ENSMUSG00000036655
  
Biological name :Colec11
  
Synonyms : Colec11 / collectin subfamily member 11
  
Possible biological names infered from orthology : Q9BWP8
  
Species: Mus musculus
  
Chr. number: 12
Strand: -1
Band: A2
Gene start: 28594173
Gene end: 28623377
  
Corresponding Affymetrix probe sets: 10399751 (MoGene1.0st)   1429179_at (Mouse Genome 430 2.0 Array)   1458345_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000049285
Ensembl peptide - ENSMUSP00000152876
Ensembl peptide - ENSMUSP00000152207
NCBI entrez gene - 71693     See in Manteia.
MGI - MGI:1918943
RefSeq - XM_017315207
RefSeq - NM_001313978
RefSeq - NM_027866
RefSeq - XM_006515221
RefSeq Peptide - NP_001300907
RefSeq Peptide - NP_082142
swissprot - A0A1Y7VLI6
swissprot - A0A1Y7VKG6
swissprot - A0A0R4J0M6
Ensembl - ENSMUSG00000036655
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 colec11ENSDARG00000013266Danio rerio
 COLEC11ENSGALG00000037309Gallus gallus
 Q9BWP8ENSG00000118004Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8CF98 / Colec10 / Collectin-10 / Q9Y6Z7* / collectin subfamily member 10*ENSMUSG0000003859146
Sftpd / P50404 / Pulmonary surfactant-associated protein D / P35247* / surfactant protein D*ENSMUSG0000002179531
Sftpa1 / surfactant associated protein A1 / SFTPA2* / Q8IWL1* / Q8IWL2* / surfactant protein A1* / surfactant protein A2*ENSMUSG0000002178925
Mbl1 / P39039 / Mannose-binding protein A ENSMUSG0000003778024
Mbl2 / P41317 / mannose-binding lectin (protein C) 2 / P11226* / mannose binding lectin 2*ENSMUSG0000002486323


Protein motifs (from Interpro)
Interpro ID Name
 IPR001304  C-type lectin-like
 IPR008160  Collagen triple helix repeat
 IPR016186  C-type lectin-like/link domain superfamily
 IPR016187  C-type lectin fold
 IPR018378  C-type lectin, conserved site
 IPR033990  Collectin, C-type lectin-like domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 cellular_componentGO:0005581 collagen trimer IEA


Pathways (from Reactome)
Pathway description
Lectin pathway of complement activation
Initial triggering of complement
Scavenging by Class A Receptors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002703 abnormal renal tubules "anomalous structure or development of the loops of Henle and collecting ducts in the kidney" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Grk1tvrm207/Grk1tvrm207
Genetic Background: B6.Cg-Grk1tvrm207/Pjn

 MP:0004042 decreased susceptibility to kidney reperfusion injury "a diminished likelihood or extent of damage to the kidney when the blood supply is restored after a period of ischemia" [brs:Beverly Richards-Smith, Mouse Genome Informatics Curator]
Show

Allelic Composition: Grk1tvrm207/Grk1tvrm207
Genetic Background: B6.Cg-Grk1tvrm207/Pjn

 MP:0005265 abnormal blood urea nitrogen level "aberrant circulating concentration of nitrogen, in the form of urea; commonly used to measure renal function" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Grk1tvrm207/Grk1tvrm207
Genetic Background: B6.Cg-Grk1tvrm207/Pjn

 MP:0011566 abnormal complement protein level "deviation from the normal levels, or accumulation of the proteins that act sequentially to allow for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes" [MGI:csmith]
Show

Allelic Composition: Grk1tvrm207/Grk1tvrm207
Genetic Background: B6.Cg-Grk1tvrm207/Pjn

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000038591 Q8CF98 / Colec10 / Collectin-10 / Q9Y6Z7* / collectin subfamily member 10*  / complex
 ENSMUSG00000073418 C4b / P01029 / Complement C4-B Complement C4 beta chain Complement C4 alpha chain C4a anaphylatoxin Complement C4 gamma chain / C4A* / P0C0L4* / P0C0L5* / complement C4B (Chido blood group)...  / reaction
 ENSMUSG00000036655 Colec11 / collectin subfamily member 11 / Q9BWP8*  / complex
 ENSMUSG00000024371 C2 / P21180 / Complement C2 Complement C2b fragment Complement C2a fragment / P06681* / complement C2*  / reaction
 ENSMUSG00000028979 Masp2 / Q91WP0 / Mannan-binding lectin serine protease 2 Mannan-binding lectin serine protease 2 A chain Mannan-binding lectin serine protease 2 B chain / O00187* / mannan binding lectin se...  / complex
 ENSMUSG00000022887 Masp1 / P98064 / Mus musculus mannan-binding lectin serine peptidase 1 (Masp1), transcript variant 1, mRNA. / P48740* / mannan binding lectin serine peptidase 1*  / complex






 

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