ENSMUSG00000040254


Mus musculus

Features
Gene ID: ENSMUSG00000040254
  
Biological name :Sema3d
  
Synonyms : Q8BH34 / Sema3d / Semaphorin-3D
  
Possible biological names infered from orthology : O95025
  
Species: Mus musculus
  
Chr. number: 5
Strand: 1
Band: A1
Gene start: 12383385
Gene end: 12588948
  
Corresponding Affymetrix probe sets: 10519693 (MoGene1.0st)   1429459_at (Mouse Genome 430 2.0 Array)   1453148_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000142453
Ensembl peptide - ENSMUSP00000030868
NCBI entrez gene - 108151     See in Manteia.
MGI - MGI:1860118
RefSeq - NM_028882
RefSeq Peptide - NP_083158
swissprot - A0A0G2JDP8
swissprot - Q8BH34
Ensembl - ENSMUSG00000040254
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sema3dENSDARG00000017369Danio rerio
 Q90663ENSGALG00000006563Gallus gallus
 O95025ENSG00000153993Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
O08665 / Sema3a / Semaphorin-3A / Q14563*ENSMUSG0000002888353
Sema3b / sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B / Q13214* / semaphorin 3B*ENSMUSG0000005796945
P70275 / Sema3e / sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E / O15041* / semaphorin 3E*ENSMUSG0000006353145
O88632 / Sema3f / Semaphorin-3F / Q13275*ENSMUSG0000003468444
Q62181 / Sema3c / Semaphorin-3C / Q99985*ENSMUSG0000002878044
Q4LFA9 / Sema3g / Semaphorin-3G / Q9NS98*ENSMUSG0000002190443
O09126 / Sema4d / Semaphorin-4D / Q92854*ENSMUSG0000002145131
Q64151 / Sema4c / Semaphorin-4C / Q9C0C4*ENSMUSG0000002612130
Q9WUH7 / Sema4g / Semaphorin-4G / Q9NTN9*ENSMUSG0000002520730
Q62179 / Sema4b / Semaphorin-4B ENSMUSG0000003053928
Q62178 / Sema4a / Semaphorin-4A / Q9H3S1*ENSMUSG0000002806427
Q9Z123 / Sema4f / Semaphorin-4F / O95754* / ssemaphorin 4F*ENSMUSG0000000062727


Protein motifs (from Interpro)
Interpro ID Name
 IPR001627  Sema domain
 IPR007110  Immunoglobulin-like domain
 IPR013783  Immunoglobulin-like fold
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR016201  PSI domain
 IPR027231  Semaphorin
 IPR036179  Immunoglobulin-like domain superfamily
 IPR036352  Sema domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0050919 negative chemotaxis IBA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0038191 neuropilin binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000266 abnormal cardiac morphology "anomalies in the hollow, muscular organ that maintains the circulation of the blood" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Ticam1Lps2/Ticam1Lps2
Genetic Background: C57BL/6J-Ticam1Lps2/J

 MP:0002726 abnormal pulmonary vein morphology "structrual anomaly of the veins that return oxygenated blood from the lungs to the left atrium of the heart" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Ticam1Lps2/Ticam1Lps2
Genetic Background: C57BL/6J-Ticam1Lps2/J

 MP:0002925 abnormal cardiovascular development "aberrant formation or incomplete differentiation of the cardiovascular system" [RGD:Rat Genome Database submission]
Show

Allelic Composition: Ticam1Lps2/Ticam1Lps2
Genetic Background: C57BL/6J-Ticam1Lps2/J

 MP:0008727 enlarged right atrium "increased size of the right upper chamber of the heart" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ticam1Lps2/Ticam1Lps2
Genetic Background: C57BL/6J-Ticam1Lps2/J

 MP:0008772 enlarged heart ventricle "increased average size of the heart ventricles compared to the average for a particular population" [MGI:rbabiuk "Randall Babiuk, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ticam1Lps2/Ticam1Lps2
Genetic Background: C57BL/6J-Ticam1Lps2/J

 MP:0010403 atrial septal defect "abnormal communications between the two upper chambers of the heart, including such defects in any or all of the ostium primum, ostium secundum, sinus venosus, and coronary sinus regions" [MESH:C14.240.400.560.375]
Show

Allelic Composition: Ticam1Lps2/Ticam1Lps2
Genetic Background: C57BL/6J-Ticam1Lps2/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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