MP:0000519 | hydronephrosis | "dilation of the pelvis and calices of one or both kidneys" [J:56641] |
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Allelic Composition: Prkar2btm1Gsm/Prkar2btm1Gsm Genetic Background: B6.129-Prkar2btm1Gsm
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MP:0001211 | wrinkled skin | "irregular folds and/or indentations on the skin" [J:19212] |
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Allelic Composition: Prkar2btm1Gsm/Prkar2btm1Gsm Genetic Background: B6.129-Prkar2btm1Gsm
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MP:0001426 | polydipsia | "excessive thirst that is relatively prolonged" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Prkar2btm1Gsm/Prkar2btm1Gsm Genetic Background: B6.129-Prkar2btm1Gsm
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MP:0001429 | dehydration | "excessive water loss from the body or from an organ or bodily part" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:50053] |
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Allelic Composition: Prkar2btm1Gsm/Prkar2btm1Gsm Genetic Background: B6.129-Prkar2btm1Gsm
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MP:0001732 | postnatal growth retardation | "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Prkar2btm1Gsm/Prkar2btm1Gsm Genetic Background: B6.129-Prkar2btm1Gsm
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MP:0001762 | polyuria | "increased volume of urine produced and excreted" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Prkar2btm1Gsm/Prkar2btm1Gsm Genetic Background: B6.129-Prkar2btm1Gsm
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MP:0002608 | increased hematocrit | "greater than average percentage of a volume of a blood sample occupied by red blood cells" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Prkar2btm1Gsm/Prkar2btm1Gsm Genetic Background: B6.129-Prkar2btm1Gsm
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MP:0002843 | decreased blood pressure | "decreased tension of the blood within the systemic arteries" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Prkar2btm1Gsm/Prkar2btm1Gsm Genetic Background: B6.129-Prkar2btm1Gsm
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MP:0002988 | decreased urine osmolarity | "reduction in the concentration of ions in the urine compared to normal" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:83000] |
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Allelic Composition: Prkar2btm1Gsm/Prkar2btm1Gsm Genetic Background: B6.129-Prkar2btm1Gsm
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MP:0003653 | decreased skin turgor | "reduced ability of the skin to resist deformation; influential factors include dehydration and age" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Prkar2btm1Gsm/Prkar2btm1Gsm Genetic Background: B6.129-Prkar2btm1Gsm
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MP:0005528 | decreased glomerular filtration rate | "less than the normal volume of water filtered out of the plasma through glomerular capillary walls into thte Bowman s capsule per unit time" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Prkar2btm1Gsm/Prkar2btm1Gsm Genetic Background: B6.129-Prkar2btm1Gsm
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MP:0005633 | increased circulating sodium level | "greater than the normal concentration in the blood of this metallic element, the most plentiful extracellular ion in the body and the principal determinant of extracellular fluid volume" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, RGD:Rat Genome Database submission] |
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Allelic Composition: Prkar2btm1Gsm/Prkar2btm1Gsm Genetic Background: B6.129-Prkar2btm1Gsm
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MP:0009643 | abnormal urine homeostasis | "anomaly in the processes involved in the maintenance of an internal equilibrium of various functions and chemical or protein composition of the urine" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Prkar2btm1Gsm/Prkar2btm1Gsm Genetic Background: B6.129-Prkar2btm1Gsm
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MP:0011086 | partial postnatal lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith] |
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Allelic Composition: Prkar2btm1Gsm/Prkar2btm1Gsm Genetic Background: B6.129-Prkar2btm1Gsm
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MP:0011296 | decreased tubuloglomerular feedback response | "attenuation of the blood flow control mechanism that is operated in the juxtaglomerular apparatus of the kidney and involved in renal autoregulation by limiting changes in the glomerular filtration rate. TGF responds to changes in the concentration of NaCl in the tubular fluid at the level of the macula densa" [MGI:anna] |
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Allelic Composition: Prkar2btm1Gsm/Prkar2btm1Gsm Genetic Background: B6.129-Prkar2btm1Gsm
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MP:0012551 | metabolic acidosis | "decreased pH and bicarbonate concentration in tissues and/or body fluids caused when the body produces too much acid or when the kidneys are not removing enough acid from the body, as in diarrhea or in kidney disease" [ISBN:0-683-40008-8] |
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Allelic Composition: Prkar2btm1Gsm/Prkar2btm1Gsm Genetic Background: B6.129-Prkar2btm1Gsm
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