ENSMUSG00000062609


Mus musculus

Features
Gene ID: ENSMUSG00000062609
  
Biological name :Kcnj15
  
Synonyms : ATP-sensitive inward rectifier potassium channel 15 / Kcnj15 / O88932
  
Possible biological names infered from orthology : potassium voltage-gated channel subfamily J member 15 / Q99712
  
Species: Mus musculus
  
Chr. number: 16
Strand: 1
Band: C4
Gene start: 95257558
Gene end: 95300260
  
Corresponding Affymetrix probe sets: 10437151 (MoGene1.0st)   1435354_at (Mouse Genome 430 2.0 Array)   1443054_at (Mouse Genome 430 2.0 Array)   1450185_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000114449
Ensembl peptide - ENSMUSP00000109493
Ensembl peptide - ENSMUSP00000114646
Ensembl peptide - ENSMUSP00000118992
Ensembl peptide - ENSMUSP00000117744
Ensembl peptide - ENSMUSP00000045218
Ensembl peptide - ENSMUSP00000109485
Ensembl peptide - ENSMUSP00000109486
Ensembl peptide - ENSMUSP00000109487
Ensembl peptide - ENSMUSP00000109489
Ensembl peptide - ENSMUSP00000109490
Ensembl peptide - ENSMUSP00000109492
NCBI entrez gene - 16516     See in Manteia.
MGI - MGI:1310000
RefSeq - XM_017316885
RefSeq - NM_001271687
RefSeq - NM_001271689
RefSeq - NM_001271690
RefSeq - NM_001271691
RefSeq - NM_001271692
RefSeq - NM_001271693
RefSeq - NM_001271694
RefSeq - NM_001271695
RefSeq - NM_019664
RefSeq - XM_006522942
RefSeq - XM_006522944
RefSeq - XM_006522945
RefSeq - XM_006522946
RefSeq - XM_006522947
RefSeq - XM_006522951
RefSeq - XM_006522952
RefSeq - XM_017316883
RefSeq - XM_017316884
RefSeq - NM_001039056
RefSeq - NM_001039057
RefSeq Peptide - NP_001258618
RefSeq Peptide - NP_001258622
RefSeq Peptide - NP_001258623
RefSeq Peptide - NP_001258624
RefSeq Peptide - NP_062638
RefSeq Peptide - NP_001034145
RefSeq Peptide - NP_001034146
RefSeq Peptide - NP_001258616
RefSeq Peptide - NP_001258619
RefSeq Peptide - NP_001258620
RefSeq Peptide - NP_001258621
swissprot - D3YXQ3
swissprot - D3YVH1
swissprot - D3YV68
swissprot - D3Z370
swissprot - O88932
swissprot - Q3TNE6
swissprot - Q53Z04
Ensembl - ENSMUSG00000062609
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 KCNJ15ENSDARG00000058988Danio rerio
 KCNJ15ENSGALG00000016055Gallus gallus
 KCNJ15ENSG00000157551Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Kcnj10 / Q9JM63 / ATP-sensitive inward rectifier potassium channel 10 / P78508* / potassium voltage-gated channel subfamily J member 10*ENSMUSG0000004470857
Kcnj1 / O88335 / ATP-sensitive inward rectifier potassium channel 1 / P48048* / potassium voltage-gated channel subfamily J member 1*ENSMUSG0000004124842
Kcnj2 / P35561 / potassium inwardly-rectifying channel, subfamily J, member 2 / P63252* / potassium voltage-gated channel subfamily J member 2*ENSMUSG0000004169535
Kcnj12 / P52187 / ATP-sensitive inward rectifier potassium channel 12 / Q14500* / potassium voltage-gated channel subfamily J member 12*ENSMUSG0000004252935
Kcnj4 / potassium voltage-gated channel subfamily J member 4 / P48050*ENSMUSG0000004421635
Kcnj14 / Q8JZN3 / ATP-sensitive inward rectifier potassium channel 14 / Q9UNX9* / potassium voltage-gated channel subfamily J member 14*ENSMUSG0000005874333
Kcnj3 / P63250 / G protein-activated inward rectifier potassium channel 1 / P48549* / potassium voltage-gated channel subfamily J member 3*ENSMUSG0000002682432
Kcnj6 / G protein-activated inward rectifier potassium channel 2 isoform Girk2B / P48051* / potassium voltage-gated channel subfamily J member 6*ENSMUSG0000004330131
Kcnj5 / P48545 / G protein-activated inward rectifier potassium channel 4 / P48544* / potassium voltage-gated channel subfamily J member 5*ENSMUSG0000003203431
Kcnj11 / Q61743 / ATP-sensitive inward rectifier potassium channel 11 / Q14654* / potassium voltage-gated channel subfamily J member 11*ENSMUSG0000009614630
Kcnj9 / P48543 / potassium inwardly-rectifying channel, subfamily J, member 9 / Q92806* / potassium voltage-gated channel subfamily J member 9*ENSMUSG0000003802630
Kcnj8 / P97794 / potassium inwardly-rectifying channel, subfamily J, member 8 / Q15842* / potassium voltage-gated channel subfamily J member 8*ENSMUSG0000003024730


Protein motifs (from Interpro)
Interpro ID Name
 IPR003270  Potassium channel, inwardly rectifying, Kir1.3
 IPR013518  Potassium channel, inwardly rectifying, Kir, cytoplasmic
 IPR014756  Immunoglobulin E-set
 IPR016449  Potassium channel, inwardly rectifying, Kir


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006813 potassium ion transport IDA
 biological_processGO:0010107 potassium ion import IBA
 biological_processGO:0034220 ion transmembrane transport IEA
 biological_processGO:0034765 regulation of ion transmembrane transport IEA
 biological_processGO:0071805 potassium ion transmembrane transport IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IC
 molecular_functionGO:0005242 inward rectifier potassium channel activity IBA
 molecular_functionGO:0005244 voltage-gated ion channel activity IEA
 molecular_functionGO:0005267 potassium channel activity IDA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Activation of G protein gated Potassium channels
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001516 abnormal motor coordination/ balance "altered ability of an animal to maintain skillful and effective interaction of movements or maintenance of equilibrium" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Adamts1tm1Dgen/Adamts1tm1Dgen
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000023439 Gnb3 / Q61011 / guanine nucleotide binding protein (G protein), beta 3 / P16520* / G protein subunit beta 3*  / complex
 ENSMUSG00000024462 Gabbr1 / Q9WV18 / Gamma-aminobutyric acid type B receptor subunit 1 / Q9UBS5*  / complex
 ENSMUSG00000062609 Kcnj15 / O88932 / ATP-sensitive inward rectifier potassium channel 15 / Q99712* / potassium voltage-gated channel subfamily J member 15*  / complex
 ENSMUSG00000029713 Gnb2 / P62880 / guanine nucleotide binding protein (G protein), beta 2 / P62879* / G protein subunit beta 2*  / complex
 ENSMUSG00000029064 Gnb1 / P62874 / guanine nucleotide binding protein (G protein), beta 1 / P62873* / G protein subunit beta 1*  / complex
 ENSMUSG00000039809 Gabbr2 / Q80T41 / Gamma-aminobutyric acid type B receptor subunit 2 / O75899*  / complex
 ENSMUSG00000051497 Kcnj16 / Q9Z307 / Inward rectifier potassium channel 16 / Q9NPI9* / potassium voltage-gated channel subfamily J member 16*  / complex






 

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contact: otassy@igbmc.fr