ENSMUSG00000096146


Mus musculus

Features
Gene ID: ENSMUSG00000096146
  
Biological name :Kcnj11
  
Synonyms : ATP-sensitive inward rectifier potassium channel 11 / Kcnj11 / Q61743
  
Possible biological names infered from orthology : potassium voltage-gated channel subfamily J member 11 / Q14654
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: B3
Gene start: 46093953
Gene end: 46100764
  
Corresponding Affymetrix probe sets: 10563480 (MoGene1.0st)   1450515_at (Mouse Genome 430 2.0 Array)   1455417_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000136002
Ensembl peptide - ENSMUSP00000148249
Ensembl peptide - ENSMUSP00000147801
Ensembl peptide - ENSMUSP00000147439
NCBI entrez gene - 16514     See in Manteia.
MGI - MGI:107501
RefSeq - XM_006540663
RefSeq - NM_001204411
RefSeq - NM_010602
RefSeq Peptide - NP_001191340
RefSeq Peptide - NP_034732
swissprot - Q61743
swissprot - A0A1C7CYV4
swissprot - A0A1B0GS56
swissprot - A0A1B0GT90
Ensembl - ENSMUSG00000096146
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 kcnj11ENSDARG00000051880Danio rerio
 KCNJ11ENSGALG00000020505Gallus gallus
 KCNJ11ENSG00000187486Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Kcnj8 / P97794 / potassium inwardly-rectifying channel, subfamily J, member 8 / Q15842* / potassium voltage-gated channel subfamily J member 8*ENSMUSG0000003024769
Kcnj12 / P52187 / ATP-sensitive inward rectifier potassium channel 12 / Q14500* / potassium voltage-gated channel subfamily J member 12*ENSMUSG0000004252944
Kcnj2 / P35561 / potassium inwardly-rectifying channel, subfamily J, member 2 / P63252* / potassium voltage-gated channel subfamily J member 2*ENSMUSG0000004169543
Kcnj6 / G protein-activated inward rectifier potassium channel 2 isoform Girk2B / P48051* / potassium voltage-gated channel subfamily J member 6*ENSMUSG0000004330143
Kcnj9 / P48543 / potassium inwardly-rectifying channel, subfamily J, member 9 / Q92806* / potassium voltage-gated channel subfamily J member 9*ENSMUSG0000003802643
Kcnj4 / potassium voltage-gated channel subfamily J member 4 / P48050*ENSMUSG0000004421643
Kcnj3 / P63250 / G protein-activated inward rectifier potassium channel 1 / P48549* / potassium voltage-gated channel subfamily J member 3*ENSMUSG0000002682442
Kcnj5 / P48545 / G protein-activated inward rectifier potassium channel 4 / P48544* / potassium voltage-gated channel subfamily J member 5*ENSMUSG0000003203441
Kcnj14 / Q8JZN3 / ATP-sensitive inward rectifier potassium channel 14 / Q9UNX9* / potassium voltage-gated channel subfamily J member 14*ENSMUSG0000005874340
Kcnj1 / O88335 / ATP-sensitive inward rectifier potassium channel 1 / P48048* / potassium voltage-gated channel subfamily J member 1*ENSMUSG0000004124838
Kcnj10 / Q9JM63 / ATP-sensitive inward rectifier potassium channel 10 / P78508* / potassium voltage-gated channel subfamily J member 10*ENSMUSG0000004470834
Kcnj15 / O88932 / ATP-sensitive inward rectifier potassium channel 15 / Q99712* / potassium voltage-gated channel subfamily J member 15*ENSMUSG0000006260931


Protein motifs (from Interpro)
Interpro ID Name
 IPR003279  Potassium channel, inwardly rectifying, Kir6.2
 IPR013518  Potassium channel, inwardly rectifying, Kir, cytoplasmic
 IPR014756  Immunoglobulin E-set
 IPR016449  Potassium channel, inwardly rectifying, Kir


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002931 response to ischemia IEA
 biological_processGO:0006006 glucose metabolic process IEA
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006813 potassium ion transport IEA
 biological_processGO:0010107 potassium ion import IDA
 biological_processGO:0032355 response to estradiol IEA
 biological_processGO:0033198 response to ATP IEA
 biological_processGO:0033574 response to testosterone IEA
 biological_processGO:0034220 ion transmembrane transport IEA
 biological_processGO:0034765 regulation of ion transmembrane transport IEA
 biological_processGO:0042391 regulation of membrane potential IEA
 biological_processGO:0042493 response to drug IEA
 biological_processGO:0046676 negative regulation of insulin secretion IEA
 biological_processGO:0050796 regulation of insulin secretion IEA
 biological_processGO:0050877 nervous system process IEA
 biological_processGO:0071316 cellular response to nicotine IEA
 biological_processGO:0071333 cellular response to glucose stimulus IEA
 biological_processGO:0071356 cellular response to tumor necrosis factor IEA
 biological_processGO:0071805 potassium ion transmembrane transport IEA
 biological_processGO:1903078 positive regulation of protein localization to plasma membrane IEA
 biological_processGO:2001259 positive regulation of cation channel activity IEA
 cellular_componentGO:0001669 acrosomal vesicle IEA
 cellular_componentGO:0005635 nuclear envelope IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0008282 inward rectifying potassium channel IDA
 cellular_componentGO:0014704 intercalated disc IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030315 T-tubule IEA
 cellular_componentGO:0030673 axolemma IEA
 cellular_componentGO:0042383 sarcolemma IEA
 cellular_componentGO:0043025 neuronal cell body IEA
 cellular_componentGO:0043209 myelin sheath IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 cellular_componentGO:0070852 cell body fiber IEA
 molecular_functionGO:0005242 inward rectifier potassium channel activity IEA
 molecular_functionGO:0005244 voltage-gated ion channel activity IEA
 molecular_functionGO:0005249 voltage-gated potassium channel activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IDA
 molecular_functionGO:0008022 protein C-terminus binding IEA
 molecular_functionGO:0015272 ATP-activated inward rectifier potassium channel activity IEA
 molecular_functionGO:0030506 ankyrin binding IPI
 molecular_functionGO:0030955 potassium ion binding IC
 molecular_functionGO:0031072 heat shock protein binding IEA
 molecular_functionGO:0044325 ion channel binding IEA


Pathways (from Reactome)
Pathway description
ATP sensitive Potassium channels
ABC-family proteins mediated transport
Ion homeostasis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000189 hypoglycemia "low levels of plasma glucose in the circulating blood; this generally refers to a pathological state" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Gaatm1Vdp/Gaatm1Vdp
Genetic Background: B6.129P2-Gaatm1Vdp

 MP:0000243 myoclonus "involuntary shock-like contractions, variable in rhythm and amplitude, followed by relaxation, of a muscle or a group of muscles; generally due to a central nervous system lesion" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Gaatm1Vdp/Gaatm1Vdp
Genetic Background: B6.129P2-Gaatm1Vdp

 MP:0000947 convulsive seizures "seizures characterized by uncontrolled motor activity" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Gaatm1Vdp/Gaatm1Vdp
Genetic Background: B6.129P2-Gaatm1Vdp

 MP:0001363 increased anxiety-related response "when compared to controls, subjects exhibit more responses thought to be indicative of anxiety in behavioral tests" [cwg:Carroll-Ann W. Goldsmith, Mouse Genome Informatics curator, J:49752, J:53060]
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Allelic Composition: Tmem100tm1.1Ysai/Tmem100tm2.1Ysai,Tg(Tek-cre)1Ywa/0
Genetic Background: involves: C57BL/6 * SJL

 MP:0001364 decreased anxiety-related response "when compared to controls, subjects exhibit fewer responses thought to be indicative of anxiety in behavioral tests" [cwg:Carroll-Ann W. Goldsmith, Mouse Genome Informatics curator, J:86626, J:85438, J:64043]
Show

Allelic Composition: Tmem100tm1.1Ysai/Tmem100tm2.1Ysai,Tg(Tek-cre)1Ywa/0
Genetic Background: involves: C57BL/6 * SJL

 MP:0001405 impaired coordination "reduced ability to execute integrated movements of muscle" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Tmem100tm1.1Ysai/Tmem100tm2.1Ysai,Tg(Tek-cre)1Ywa/0
Genetic Background: involves: C57BL/6 * SJL

 MP:0001417 decreased exploration in new environment "less amount of time spent investigating a new location" [J:79870]
Show

Allelic Composition: Tmem100tm1.1Ysai/Tmem100tm2.1Ysai,Tg(Tek-cre)1Ywa/0
Genetic Background: involves: C57BL/6 * SJL

 MP:0002066 abnormal motor capabilities/coordination/movement "altered ability to coordinate voluntary movement or repetitive, compulsive movements" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Tmem100tm1.1Ysai/Tmem100tm2.1Ysai,Tg(Tek-cre)1Ywa/0
Genetic Background: involves: C57BL/6 * SJL

 MP:0002078 abnormal glucose homeostasis "anomaly in the state of equilibrium or processing in the body with respect to glucose in the fluids and tissues" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Gaatm1Vdp/Gaatm1Vdp
Genetic Background: B6.129P2-Gaatm1Vdp

 MP:0002079 increased circulating insulin level "greater than normal levels of insulin in blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: B2mtm1Unc/B2mtm1Unc,Tespa1tm1Lrgl/Tespa1tm1Lrgl
Genetic Background: involves: 129 * 129P2/OlaHsd * C57BL/6

 MP:0002572 abnormal emotion/affect behavior "altered response in tests for emotional related behaviors" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Tmem100tm1.1Ysai/Tmem100tm2.1Ysai,Tg(Tek-cre)1Ywa/0
Genetic Background: involves: C57BL/6 * SJL

 MP:0002711 decreased glucagon secretion "less than normal release of this hormone secreted by the alpha cells of the islets of Langerhans; it normally plays a role in regulation of blood glucose concentration, ketone metabolism, and other biochemical and physiological processes " [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Gaatm1Vdp/Gaatm1Vdp
Genetic Background: B6.129P2-Gaatm1Vdp

Allelic Composition: Kcnj11Y12stop/Kcnj11Y12stop
Genetic Background: involves: BALB/c * C3H/HeH

 MP:0002727 decreased circulating insulin level "less than normal levels of insulin in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, dlb:Donna Burkart , Mouse Genome Informatics Curator]
Show

Allelic Composition: Gaatm1Vdp/Gaatm1Vdp
Genetic Background: B6.129P2-Gaatm1Vdp

 MP:0002757 reduced vertical activity "lesser than average time spent jumping or rearing" [J:82829, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Tmem100tm1.1Ysai/Tmem100tm2.1Ysai,Tg(Tek-cre)1Ywa/0
Genetic Background: involves: C57BL/6 * SJL

 MP:0002841 impaired skeletal muscle contractility "inability or reduced ability of the skeletal muscle to shorten or to develop increased tension" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Gaatm1Vdp/Gaatm1Vdp
Genetic Background: B6.129P2-Gaatm1Vdp

 MP:0002891 increased insulin sensitivity "greater ability to clear glucose from the bloodstream when given insulin than normal; can result in hypoglycemia" [RGD:Rat Genome Database submission]
Show

Allelic Composition: Gaatm1Vdp/Gaatm1Vdp
Genetic Background: B6.129P2-Gaatm1Vdp

 MP:0003058 increased insulin secretion "greater than normal release of this hormone secreted by beta cells of the pancreas, that promotes glucose utilization, protein synthesis, and the formation and storage of neutral lipids " [MeSH:National Library of Medicine - Medical Subject Headings, 2003, RGD:Rat Genome Database submission]
Show

Allelic Composition: Kcnj11Y12stop/Kcnj11Y12stop
Genetic Background: involves: BALB/c * C3H/HeH

Allelic Composition: Kcnj11tm1Sse/Kcnj11+,Tg(Ins1-Kcnj11*)#Nich/?
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CBA

 MP:0003059 decreased insulin secretion "less than normal release of this hormone secreted by beta cells of the pancreas, that promotes glucose utilization, protein synthesis, and the formation and storage of neutral lipids " [MeSH:National Library of Medicine - Medical Subject Headings, 2003, RGD:Rat Genome Database submission]
Show

Allelic Composition: Kcnj11tm1Sse/Kcnj11+,Tg(Ins1-Kcnj11*)#Nich/?
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CBA

Allelic Composition: Kcnj11tm1Sse/Kcnj11tm1Sse,Tg(Ins1-Kcnj11*)#Nich/?
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CBA

 MP:0003061 decreased aerobic running capacity "reduced ability to run at defined speeds and/or distances compared to controls" [RGD:Rat Genome Database submission]
Show

Allelic Composition: Gaatm1Vdp/Gaatm1Vdp
Genetic Background: B6.129P2-Gaatm1Vdp

 MP:0003313 abnormal locomotor activation "altered ability or desire of an animal to initiate locomotor activity" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Gaatm1Vdp/Gaatm1Vdp
Genetic Background: B6.129P2-Gaatm1Vdp

Allelic Composition: Kcnj11tm1Sse/Kcnj11tm1Sse
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0003477 abnormal nerve fiber response "anomaly in the electrophysiological recordings from a single or several nerve fiber(s)" [Nmice:Neuromice Consortium Submission]
Show

Allelic Composition: Gaatm1Vdp/Gaatm1Vdp
Genetic Background: B6.129P2-Gaatm1Vdp

Allelic Composition: Kcnj11tm1Sse/Kcnj11tm1Sse
Genetic Background: involves: 129P2/OlaHsd

 MP:0003479 abnormal nerve fiber response intensity 
Show

Allelic Composition: Kcnj11tm1Sse/Kcnj11tm1Sse
Genetic Background: involves: 129P2/OlaHsd

 MP:0003562 abnormal beta cell physiology "anomaly in the function of the insulin-producing cells of the islets of Langerhans in the pancreas" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Kcnj11tm1Sse/Kcnj11+,Tg(Ins1-Kcnj11*)#Nich/?
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CBA

 MP:0003646 muscle fatigue "increased muscle exhaustion or increased susceptibility to muscle exhaustion" [J:96306]
Show

Allelic Composition: Kcnj11tm1Sse/Kcnj11tm1Sse
Genetic Background: involves: 129P2/OlaHsd

 MP:0003997 tonic-clonic seizures "increased number or decreased threshold for the induction of a seizure characterized by initial rigidity followed by rhythmic jerking movements" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Kcnj11tm1Sse/Kcnj11tm1Sse
Genetic Background: involves: 129P2/OlaHsd

 MP:0004036 abnormal muscle relaxation "altered ability of the muscle to lengthen following contractions" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
Show

Allelic Composition: Kcnj11tm1Sse/Kcnj11tm1Sse
Genetic Background: involves: 129P2/OlaHsd

 MP:0004875 increased mean arterial blood pressure "increase in the average arterial pressure during a single cardiac cycle" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Gaatm1Vdp/Gaatm1Vdp
Genetic Background: B6.129P2-Gaatm1Vdp

 MP:0004889 increased energy expenditure "increase in the number of calories used per unit time or decrease in weight gain for a given amount of food eaten" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Gaatm1Vdp/Gaatm1Vdp
Genetic Background: B6.129P2-Gaatm1Vdp

 MP:0005289 increased oxygen consumption "greater than the normal rate at which oxygen enters the blood from alveolar gas; this is equal in the steady state to the consumption of oxygen by tissue metabolism throughout the body" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Gaatm1Vdp/Gaatm1Vdp
Genetic Background: B6.129P2-Gaatm1Vdp

 MP:0005292 improved glucose tolerance "better than the normal response to oral consumption or intravenous injection of specified amounts of glucose and indicative of insulin sensitivity; measured by determining whole blood or plasma sugar level in a fasting state before and after taking glucose at specified intervals" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: B2mtm1Unc/B2mtm1Unc,Tespa1tm1Lrgl/Tespa1tm1Lrgl
Genetic Background: involves: 129 * 129P2/OlaHsd * C57BL/6

 MP:0005293 impaired glucose tolerance "less than the normal response to oral consumption or intravenous injection of specified amounts of glucose and indicative of insulin resistance; measured by determining whole blood or plasma sugar level in a fasting state before and after taking glucose at specified intervals" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Gaatm1Vdp/Gaatm1Vdp
Genetic Background: B6.129P2-Gaatm1Vdp

Allelic Composition: Kcnj11tm1Sse/Kcnj11+,Tg(Ins1-Kcnj11*)#Nich/?
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CBA

Allelic Composition: Kcnj11tm1Sse/Kcnj11tm1Sse,Tg(Ins1-Kcnj11*)#Nich/?
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CBA

Allelic Composition: Kcnj11tm1b(EUCOMM)Wtsi/Kcnj11tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Kcnj11tm1b(EUCOMM)Wtsi/H

 MP:0005402 abnormal action potential "change in the electric response of a nerve or other excitable tissue to its stimulation" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Gaatm1Vdp/Gaatm1Vdp
Genetic Background: B6.129P2-Gaatm1Vdp

 MP:0005449 abnormal food intake "anomalous total number of calories taken in daily when compared to the norm" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Gaatm1Vdp/Gaatm1Vdp
Genetic Background: B6.129P2-Gaatm1Vdp

 MP:0005522 increased circulating atrial natriuretic factor "greater than the normal concentration of this peptide hormone in the blood; it regulates the water-electrolyte balance and acts as a vasodilator" [RGD:Rat Genome Database submission, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Gaatm1Vdp/Gaatm1Vdp
Genetic Background: B6.129P2-Gaatm1Vdp

 MP:0005559 increased circulating glucose level "greater than the normal concentration in the blood of this major monosaccharide of the body; it is an important energy source" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, RGD:Rat Genome Database submission]
Show

Allelic Composition: Kcnj11tm1Sse/Kcnj11+,Tg(Ins1-Kcnj11*)#Nich/?
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CBA

Allelic Composition: Kcnj11tm1Sse/Kcnj11tm1Sse,Tg(Ins1-Kcnj11*)#Nich/?
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CBA

 MP:0005659 resistance to diet-induced obesity "less likely to become excessively fat or to increase fat in the subcutaneous connective tissue as a result of consuming a diet geared to increase body fat " [cwg:Carroll-Ann W. Goldsmith, Mouse Genome Informatics curator]
Show

Allelic Composition: Gaatm1Vdp/Gaatm1Vdp
Genetic Background: B6.129P2-Gaatm1Vdp

 MP:0008414 abnormal spatial reference memory "anomaly in the ability to recall spatial location information from previous encounters or training sessions in order to naviagate or perform other behavior using such locational cues" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Kcnj11tm1Sse/Kcnj11tm1Sse
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0008489 postnatal slow weight gain "the weight gain over a span of postnatal developmental time is slower than controls, with or without ever attaining a similar weight to controls as adults" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Gaatm1Vdp/Gaatm1Vdp
Genetic Background: B6.129P2-Gaatm1Vdp

 MP:0008844 decreased subcutaneous adipose tissue amount "reduction in amount of adipose tissue beneath the skin" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Gaatm1Vdp/Gaatm1Vdp
Genetic Background: B6.129P2-Gaatm1Vdp

 MP:0009287 decreased abdominal fat pad weight "less than average weight of the encapsulated adipose tissue in the abdomen" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Gaatm1Vdp/Gaatm1Vdp
Genetic Background: B6.129P2-Gaatm1Vdp

 MP:0009763 increased sensitivity to induced morbidity/mortality "decrease in the amount of an external agent required to cause death or diseased state" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Kcnj11tm1Sse/Kcnj11tm1Sse
Genetic Background: involves: 129P2/OlaHsd

 MP:0013278 decreased fasted circulating glucose level "reduction in the amount of glucose in the blood at some defined time point after eating compared to controls" [MGI:Armida_Di_Fenza]
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Allelic Composition: Kcnj11tm1b(EUCOMM)Wtsi/Kcnj11tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Kcnj11tm1b(EUCOMM)Wtsi/H

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000030249 Abcc9 / P70170 / ATP-binding cassette, sub-family C (CFTR/MRP), member 9 / O60706* / ATP binding cassette subfamily C member 9*  / complex
 ENSMUSG00000096146 Kcnj11 / Q61743 / ATP-sensitive inward rectifier potassium channel 11 / Q14654* / potassium voltage-gated channel subfamily J member 11*  / complex
 ENSMUSG00000030247 Kcnj8 / P97794 / potassium inwardly-rectifying channel, subfamily J, member 8 / Q15842* / potassium voltage-gated channel subfamily J member 8*  / complex






 

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