ENSMUSG00000048076


Mus musculus

Features
Gene ID: ENSMUSG00000048076
  
Biological name :Arf1
  
Synonyms : ADP-ribosylation factor 1 / Arf1 / P84078
  
Possible biological names infered from orthology :
  
Species: Mus musculus
  
Chr. number: 11
Strand: -1
Band: B1.3
Gene start: 59211412
Gene end: 59228270
  
Corresponding Affymetrix probe sets: 10386370 (MoGene1.0st)   10456974 (MoGene1.0st)   1420920_a_at (Mouse Genome 430 2.0 Array)   1426390_a_at (Mouse Genome 430 2.0 Array)   1426391_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000079905
Ensembl peptide - ENSMUSP00000126120
NCBI entrez gene - 11840     See in Manteia.
MGI - MGI:99431
RefSeq - NM_001130408
RefSeq - NM_007476
RefSeq Peptide - NP_001123880
RefSeq Peptide - NP_031502
swissprot - P84078
Ensembl - ENSMUSG00000048076
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Arf2 / Q8BSL7 / ADP-ribosylation factor 2 ENSMUSG0000006242196
Arf3 / P61205 / ADP-ribosylation factor 3 / P61204*ENSMUSG0000005185396
Arf4 / P61750 / ADP-ribosylation factor 4 / P18085*ENSMUSG0000002187781
Arf5 / P84084 / ADP-ribosylation factor 5 / P84085*ENSMUSG0000002044080
Arf6 / P62331 / ADP-ribosylation factor 6 / P62330*ENSMUSG0000004414767
Q8BGX0 / Trim23 / E3 ubiquitin-protein ligase TRIM23 / P36406* / tripartite motif containing 23*ENSMUSG0000002171260
Arl2 / Q9D0J4 / ADP-ribosylation factor-like protein 2 / P36404* / ARL2-SNX15* / ADP ribosylation factor like GTPase 2* / ARL2-SNX15 readthrough (NMD candidate)*ENSMUSG0000002494447
Arl3 / Q9WUL7 / ADP-ribosylation factor-like protein 3 / P36405* / ADP ribosylation factor like GTPase 3*ENSMUSG0000002503545
Arl14 / ADP ribosylation factor like GTPase 14 / Q8N4G2*ENSMUSG0000009820743
Arl11 / Q6P3A9 / ADP-ribosylation factor-like protein 11 / Q969Q4* / ADP ribosylation factor like GTPase 11*ENSMUSG0000004315741
Arl8b / Q9CQW2 / ADP-ribosylation factor-like protein 8B / Q9NVJ2* / ADP ribosylation factor like GTPase 8B*ENSMUSG0000003010533
Arl8a / Q8VEH3 / ADP-ribosylation factor-like protein 8A / Q96BM9* / ADP ribosylation factor like GTPase 8A*ENSMUSG0000002642632
Arl15 / Q8BGR6 / ADP-ribosylation factor-like protein 15 / Q9NXU5* / ADP ribosylation factor like GTPase 15*ENSMUSG0000004234832


Protein motifs (from Interpro)
Interpro ID Name
 IPR005225  Small GTP-binding protein domain
 IPR006689  Small GTPase superfamily, ARF/SAR type
 IPR024156  Small GTPase superfamily, ARF type
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002090 regulation of receptor internalization IEA
 biological_processGO:0006878 cellular copper ion homeostasis ISO
 biological_processGO:0007015 actin filament organization IEA
 biological_processGO:0015031 protein transport TAS
 biological_processGO:0016192 vesicle-mediated transport IDA
 biological_processGO:0034315 regulation of Arp2/3 complex-mediated actin nucleation IEA
 biological_processGO:0034379 very-low-density lipoprotein particle assembly IEA
 biological_processGO:0043085 positive regulation of catalytic activity IEA
 biological_processGO:0045807 positive regulation of endocytosis IEA
 biological_processGO:0045956 positive regulation of calcium ion-dependent exocytosis IEA
 biological_processGO:0050714 positive regulation of protein secretion IEA
 biological_processGO:0055108 Golgi to transport vesicle transport IEA
 biological_processGO:0060292 long term synaptic depression IEA
 biological_processGO:0060999 positive regulation of dendritic spine development IEA
 biological_processGO:0070142 synaptic vesicle budding IEA
 biological_processGO:0097061 dendritic spine organization IEA
 biological_processGO:0097212 lysosomal membrane organization IEA
 biological_processGO:0098586 cellular response to virus ISO
 biological_processGO:1902307 positive regulation of sodium ion transmembrane transport IEA
 biological_processGO:1902824 positive regulation of late endosome to lysosome transport IEA
 biological_processGO:1902953 positive regulation of ER to Golgi vesicle-mediated transport IEA
 biological_processGO:1903725 regulation of phospholipid metabolic process IEA
 biological_processGO:1990386 mitotic cleavage furrow ingression IGI
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005770 late endosome IEA
 cellular_componentGO:0005778 peroxisomal membrane IEA
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0005802 trans-Golgi network IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0012505 endomembrane system IDA
 cellular_componentGO:0014069 postsynaptic density IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030017 sarcomere IDA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030137 COPI-coated vesicle IEA
 cellular_componentGO:0031252 cell leading edge ISO
 cellular_componentGO:0032991 protein-containing complex IMP
 cellular_componentGO:0043005 neuron projection IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000287 magnesium ion binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005525 GTP binding IMP
 molecular_functionGO:0019003 GDP binding IEA
 molecular_functionGO:0019904 protein domain specific binding ISO
 molecular_functionGO:0046982 protein heterodimerization activity ISO
 molecular_functionGO:1990583 phospholipase D activator activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0011096 complete embryonic lethality before somite formation "death of all organisms of a given genotype in a population between the point of implantation and somite formation (Mus: E4.5 to less than E8)" [MGI:csmith]
Show

Allelic Composition: Elfn1tm1.1Jaru/Elfn1tm1.1Jaru
Genetic Background: involves: C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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