ENSMUSG00000024944


Mus musculus

Features
Gene ID: ENSMUSG00000024944
  
Biological name :Arl2
  
Synonyms : ADP-ribosylation factor-like protein 2 / Arl2 / Q9D0J4
  
Possible biological names infered from orthology : ADP ribosylation factor like GTPase 2 / ARL2-SNX15 / ARL2-SNX15 readthrough (NMD candidate) / P36404
  
Species: Mus musculus
  
Chr. number: 19
Strand: -1
Band: A
Gene start: 6134374
Gene end: 6141406
  
Corresponding Affymetrix probe sets: 10465388 (MoGene1.0st)   1422549_at (Mouse Genome 430 2.0 Array)   1458565_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000025893
NCBI entrez gene - 56327     See in Manteia.
MGI - MGI:1928393
RefSeq - NM_019722
RefSeq Peptide - NP_062696
swissprot - Q9D0J4
Ensembl - ENSMUSG00000024944
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 arl2ENSDARG00000069496Danio rerio
 ARL2ENSG00000213465Homo sapiens
 ARL2-SNX15ENSG00000273003Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Arl3 / Q9WUL7 / ADP-ribosylation factor-like protein 3 / P36405* / ADP ribosylation factor like GTPase 3*ENSMUSG0000002503552
Arf4 / P61750 / ADP-ribosylation factor 4 / P18085*ENSMUSG0000002187746
Arf5 / P84084 / ADP-ribosylation factor 5 / P84085*ENSMUSG0000002044046
Arf2 / Q8BSL7 / ADP-ribosylation factor 2 ENSMUSG0000006242146
Arf3 / P61205 / ADP-ribosylation factor 3 / P61204*ENSMUSG0000005185346
Arf1 / P84078 / ADP-ribosylation factor 1 ENSMUSG0000004807646
Arf6 / P62331 / ADP-ribosylation factor 6 / P62330*ENSMUSG0000004414744
Q8BGX0 / Trim23 / E3 ubiquitin-protein ligase TRIM23 / P36406* / tripartite motif containing 23*ENSMUSG0000002171243
Arl11 / Q6P3A9 / ADP-ribosylation factor-like protein 11 / Q969Q4* / ADP ribosylation factor like GTPase 11*ENSMUSG0000004315739
Arl14 / ADP ribosylation factor like GTPase 14 / Q8N4G2*ENSMUSG0000009820738
Arl8b / Q9CQW2 / ADP-ribosylation factor-like protein 8B / Q9NVJ2* / ADP ribosylation factor like GTPase 8B*ENSMUSG0000003010531
Arl8a / Q8VEH3 / ADP-ribosylation factor-like protein 8A / Q96BM9* / ADP ribosylation factor like GTPase 8A*ENSMUSG0000002642631
Arl15 / Q8BGR6 / ADP-ribosylation factor-like protein 15 / Q9NXU5* / ADP ribosylation factor like GTPase 15*ENSMUSG0000004234829


Protein motifs (from Interpro)
Interpro ID Name
 IPR005225  Small GTP-binding protein domain
 IPR006689  Small GTPase superfamily, ARF/SAR type
 IPR024156  Small GTPase superfamily, ARF type
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007098 centrosome cycle ISS
 biological_processGO:0010811 positive regulation of cell-substrate adhesion ISS
 biological_processGO:0031113 regulation of microtubule polymerization ISO
 biological_processGO:0031116 positive regulation of microtubule polymerization ISO
 biological_processGO:0034260 negative regulation of GTPase activity ISO
 biological_processGO:0051457 maintenance of protein location in nucleus ISS
 biological_processGO:0070830 bicellular tight junction assembly ISS
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005730 nucleolus ISO
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005758 mitochondrial intermembrane space ISO
 cellular_componentGO:0005794 Golgi apparatus ISO
 cellular_componentGO:0005813 centrosome ISS
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005925 focal adhesion ISO
 cellular_componentGO:0016328 lateral plasma membrane ISS
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005525 GTP binding ISO
 molecular_functionGO:0019003 GDP binding IDA


Pathways (from Reactome)
Pathway description
Regulation of insulin secretion


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000031776 Arl2bp / Q9D385 / ADP-ribosylation factor-like protein 2-binding protein / Q9Y2Y0* / ADP ribosylation factor like GTPase 2 binding protein*  / complex / reaction
 ENSMUSG00000031633 P48962 / Slc25a4 / solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4 / P12235* / solute carrier family 25 member 4*  / reaction / complex






 

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