ENSMUSG00000049100


Mus musculus

Features
Gene ID: ENSMUSG00000049100
  
Biological name :Pcdh10
  
Synonyms : Pcdh10 / protocadherin 10
  
Possible biological names infered from orthology : Q9P2E7
  
Species: Mus musculus
  
Chr. number: 3
Strand: 1
Band: B
Gene start: 45378398
Gene end: 45435623
  
Corresponding Affymetrix probe sets: 10491885 (MoGene1.0st)   1421311_at (Mouse Genome 430 2.0 Array)   1425563_s_at (Mouse Genome 430 2.0 Array)   1430667_at (Mouse Genome 430 2.0 Array)   1438134_at (Mouse Genome 430 2.0 Array)   1442565_at (Mouse Genome 430 2.0 Array)   1444301_at (Mouse Genome 430 2.0 Array)   1444452_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000141529
Ensembl peptide - ENSMUSP00000131073
Ensembl peptide - ENSMUSP00000131600
Ensembl peptide - ENSMUSP00000132769
NCBI entrez gene - 18526     See in Manteia.
MGI - MGI:1338042
RefSeq - NM_001098171
RefSeq - NM_001098170
RefSeq - NM_001098172
RefSeq - NM_011043
RefSeq Peptide - NP_001091642
RefSeq Peptide - NP_001091640
RefSeq Peptide - NP_035173
RefSeq Peptide - NP_001091641
swissprot - E9PX28
swissprot - Q925I8
swissprot - E9PXQ7
swissprot - Q6P0A6
Ensembl - ENSMUSG00000049100
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pcdh10aENSDARG00000099729Danio rerio
 PCDH10ENSG00000138650Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Pcdh17 / protocadherin 17 / O14917*ENSMUSG0000003556638
Pcdh19 / Q80TF3 / Protocadherin-19 / Q8TAB3*ENSMUSG0000005132337
Pcdh18 / Q8VHR0 / Protocadherin 18 / Q9HCL0*ENSMUSG0000003789235
Pcdhga8 / protocadherin gamma subfamily A, 8 / Q9Y5G5*ENSMUSG0000010389735
Pcdhac2ENSMUSG0000010269735
Pcdhga7 / protocadherin gamma subfamily A, 7 / Q9Y5G6*ENSMUSG0000010347234
Pcdhga11 / protocadherin gamma subfamily A, 11 / Q9Y5H2*ENSMUSG0000010274234
Pcdhga10 / protocadherin gamma subfamily A, 10 / Q9Y5H3*ENSMUSG0000010222234
Q91XY4 / Pcdhga4 / Protocadherin gamma-A4 / Q9Y5G9* / protocadherin gamma subfamily A, 4*ENSMUSG0000010367734
Pcdhga5 / protocadherin gamma subfamily A, 5 / Q9Y5G8*ENSMUSG0000010356733
Pcdhga6 / protocadherin gamma subfamily A, 6 / Q9Y5G7*ENSMUSG0000010379333
Pcdhga3 / protocadherin gamma subfamily A, 3 / Q9Y5H0*ENSMUSG0000010434633
Pcdha2 / protocadherin alpha 2ENSMUSG0000010414833
Pcdha3 / protocadherin alpha 3ENSMUSG0000010231232
Pcdh8 / Q7TSK3 / Protocadherin-8 / O95206*ENSMUSG0000003642231
O55134 / Pcdh12 / Protocadherin-12 / Q9NPG4*ENSMUSG0000002444029


Protein motifs (from Interpro)
Interpro ID Name
 IPR002126  Cadherin
 IPR013164  Cadherin, N-terminal
 IPR015919  Cadherin-like
 IPR020894  Cadherin conserved site
 IPR030712  Protocadherin-10
 IPR032455  Cadherin, cytoplasmic C-terminal domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IDA
 biological_processGO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules IDA
 biological_processGO:0007267 cell-cell signaling IBA
 biological_processGO:0007399 nervous system development IBA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane ISS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005509 calcium ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000787 abnormal telencephalon morphology "any malformation or absence of the paired anteriolateral division of the prosencephalon plus the lamina terminalis from which the olfactory lobes, cerebral cortex, and subcortical nuclei are derived " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: PhexHyp/Y
Genetic Background: B6.Cg-PhexHyp/J

 MP:0001265 reduced body size "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]
Show

Allelic Composition: PhexHyp/Y
Genetic Background: B6.Cg-PhexHyp/J

 MP:0002152 abnormal brain morphology "anomalous structure of or abnormal development of the brain, one of the two components of the central nervous system and the center of thought and emotion; controls coordination, bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, http://cancerweb.ncl.ac.uk]
Show

Allelic Composition: PhexHyp/Y
Genetic Background: B6.Cg-PhexHyp/J

 MP:0011085 complete postnatal lethality "premature death anytime between the neonatal period and weaning age of all organisms of a given genotype in a population (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
Show

Allelic Composition: PhexHyp/Y
Genetic Background: B6.Cg-PhexHyp/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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