ENSMUSG00000058672


Mus musculus

Features
Gene ID: ENSMUSG00000058672
  
Biological name :Tubb2a
  
Synonyms : Q7TMM9 / Tubb2a / tubulin, beta 2A class IIA
  
Possible biological names infered from orthology : Q13885
  
Species: Mus musculus
  
Chr. number: 13
Strand: -1
Band: A3.3
Gene start: 34074274
Gene end: 34078007
  
Corresponding Affymetrix probe sets: 10408610 (MoGene1.0st)   1427347_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000060246
NCBI entrez gene - 22151     See in Manteia.
MGI - MGI:107861
RefSeq - NM_009450
RefSeq Peptide - NP_033476
swissprot - Q7TMM9
Ensembl - ENSMUSG00000058672
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tubb2ENSDARG00000039522Danio rerio
 Q13885ENSG00000137267Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9CWF2 / Tubb2b / tubulin, beta 2B class IIB / Q9BVA1*ENSMUSG00000045136100
P68372 / Tubb4b / tubulin, beta 4B class IVB / P68371*ENSMUSG0000003675296
Q9D6F9 / Tubb4a / tubulin, beta 4A class IVA / P04350*ENSMUSG0000006259195
Tubb5 / P99024 / tubulin, beta 5 class I / TUBB* / P07437* / tubulin beta class I*ENSMUSG0000000152595
Tubb3 / Q9ERD7 / tubulin, beta 3 class III / Q13509*ENSMUSG0000006238092
Tubb6 / Q922F4 / tubulin, beta 6 class V / Q9BUF5*ENSMUSG0000000147391
Tubb1 / A2AQ07 / tubulin, beta 1 class VI / Q9H4B7*ENSMUSG0000001625579
Tube1 / Q9D6T1 / epsilon-tubulin 1 / Q9UJT0* / tubulin epsilon 1*ENSMUSG0000001984533
Tubd1 / Q9R1K7 / tubulin, delta 1 / Q9UJT1*ENSMUSG0000002051323


Protein motifs (from Interpro)
Interpro ID Name
 IPR000217  Tubulin
 IPR002453  Beta tubulin
 IPR003008  Tubulin/FtsZ, GTPase domain
 IPR008280  Tubulin/FtsZ, C-terminal
 IPR013838  Beta tubulin, autoregulation binding site
 IPR017975  Tubulin, conserved site
 IPR018316  Tubulin/FtsZ, 2-layer sandwich domain
 IPR036525  Tubulin/FtsZ, GTPase domain superfamily
 IPR037103  Tubulin/FtsZ, C-terminal domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007010 cytoskeleton organization IEA
 biological_processGO:0007017 microtubule-based process IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005874 microtubule ISO
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005200 structural constituent of cytoskeleton IEA
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane
MHC class II antigen presentation
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
HSP90 chaperone cycle for steroid hormone receptors (SHR)
Recruitment of NuMA to mitotic centrosomes
Recycling pathway of L1
Hedgehog off state
Cilium Assembly
Intraflagellar transport
RHO GTPases activate IQGAPs
Hedgehog on state
RHO GTPases Activate Formins
COPI-mediated anterograde transport
COPI-dependent Golgi-to-ER retrograde traffic
COPI-independent Golgi-to-ER retrograde traffic
Mitotic Prometaphase
The role of GTSE1 in G2/M progression after G2 checkpoint
Carboxyterminal post-translational modifications of tubulin
Kinesins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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