Manteia

ENSMUSG00000091512

Mus musculus

Features

Gene ID:	ENSMUSG00000091512

Biological name :	Lamtor3

Synonyms :	Lamtor3 / late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 / O88653

Possible biological names infered from orthology :	Q9UHA4

Species:	Mus musculus

Chr. number:	3
Strand:	1
Band:	G3
Gene start:	137918506
Gene end:	137928900

Corresponding Affymetrix probe sets:	10496397 (MoGene1.0st) 10566405 (MoGene1.0st) 1416272_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000143656 Ensembl peptide - ENSMUSP00000130811 Ensembl peptide - ENSMUSP00000142512 NCBI entrez gene - 56692 See in Manteia. MGI - MGI:1929467 RefSeq - NM_019920 RefSeq Peptide - NP_064304 swissprot - A0A0G2JGQ3 swissprot - O88653 swissprot - Q542I7 Ensembl - ENSMUSG00000091512

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Paralog prediction (from Ensembl)

Paralog name

Similarity(%)

No match

Protein motifs (from Interpro)

Interpro ID	Name
IPR015019	Ragulator complex protein LAMTOR3

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0000186	activation of MAPKK activity	IDA
biological_process	GO:0032006	regulation of TOR signaling	IEA
biological_process	GO:0032008	positive regulation of TOR signaling	IEA
biological_process	GO:0034613	cellular protein localization	IEA
biological_process	GO:0065009	regulation of molecular function	IEA
biological_process	GO:0071230	cellular response to amino acid stimulus	IEA
cellular_component	GO:0005768	endosome	IEA
cellular_component	GO:0005770	late endosome	IDA
cellular_component	GO:0016020	membrane	IEA
cellular_component	GO:0031902	late endosome membrane	IEA
cellular_component	GO:0071986	Ragulator complex	IEA
molecular_function	GO:0005085	guanyl-nucleotide exchange factor activity	IEA
molecular_function	GO:0005515	protein binding	IPI
molecular_function	GO:0019209	kinase activator activity	IDA
molecular_function	GO:0032947	protein-containing complex scaffold activity	IEA

Pathways (from Reactome)

Pathway description

Macroautophagy

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID	Name	Interaction type
ENSMUSG00000000441	Raf1 / Q99N57 / Mus musculus v-raf-leukemia viral onco 1 (Raf1), transcript variant 3, mRNA. / P04049* / Raf-1 proto-oncogene, serine/threonine kinase*	/ complex / reaction
ENSMUSG00000002413	Braf / P28028 / Serine/threonine-protein kinase B-raf / P15056* / B-Raf proto-oncogene, serine/threonine kinase*	/ complex / reaction
ENSMUSG00000028062	Q9JHS3 / Lamtor2 / Ragulator complex protein LAMTOR2 / Q9Y2Q5* / late endosomal/lysosomal adaptor, MAPK and MTOR activator 2*	/ complex
ENSMUSG00000063358	Mapk1 / P63085 / Mus musculus mitogen-activated protein kinase 1 (Mapk1), transcript variant 3, mRNA. / P28482* / mitogen-activated protein kinase 1*	/ complex / reaction
ENSMUSG00000063065	Mapk3 / Q63844 / Mitogen-activated protein kinase 3 / P27361*	/ reaction / complex
ENSMUSG00000035027	Q63932 / Map2k2 / Mus musculus mitogen-activated protein kinase kinase 2 (Map2k2), transcript variant 2, mRNA. / P36507* / AC011005.1* / mitogen-activated protein kinase kinase 2*	/ reaction / complex
ENSMUSG00000005150	Wdr83 / Q9DAJ4 / WD repeat domain containing 83 / Q9BRX9* / WD repeat domain 83*	/ complex
ENSMUSG00000004936	Map2k1 / P31938 / Dual specificity mitogen-activated protein kinase kinase 1 / Q02750* / mitogen-activated protein kinase kinase 1*	/ complex / reaction

1 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr