ENSDARG00000033160


Danio rerio

Features
Gene ID: ENSDARG00000033160
  
Biological name :nr1d1
  
Synonyms : nr1d1 / nuclear receptor subfamily 1, group d, member 1
  
Possible biological names infered from orthology : P20393 / Q3UV55
  
Species: Danio rerio
  
Chr. number: 3
Strand: 1
Band:
Gene start: 23488652
Gene end: 23496223
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000104933
NCBI entrez gene - 494487     See in Manteia.
RefSeq - NM_205729
RefSeq Peptide - NP_991292
swissprot - F1RAU6
ZFIN ID - ZDB-GENE-050105-1
Ensembl - ENSDARG00000033160
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 NR1D1ENSG00000126368Homo sapiens
 Nr1d1ENSMUSG00000020889Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
nr1d2b / nuclear receptor subfamily 1, group D, member 2b / NR1D2* / Q60674* / Q14995* / nuclear receptor subfamily 1 group D member 2*ENSDARG0000000959445
nr1d2a / nuclear receptor subfamily 1, group D, member 2aENSDARG0000000382041
nr1d4a / nuclear receptor subfamily 1, group D, member 4aENSDARG0000003116140
nr1d4b / nuclear receptor subfamily 1, group D, member 4bENSDARG0000005937039
pparaa / peroxisome proliferator-activated receptor alpha a / PPARA* / P23204* / Q07869* / peroxisome proliferator activated receptor alpha*ENSDARG0000003177722
rorb / RAR-related orphan receptor B / Q8R1B8* / Q92753* / Nuclear receptor ROR-beta *ENSDARG0000003349821
pparab / peroxisome proliferator-activated receptor alpha b / PPARA* / P23204* / Q07869* / peroxisome proliferator activated receptor alpha*ENSDARG0000005432321
rorab / RAR-related orphan receptor A, paralog bENSDARG0000000191021
roraa / RAR-related orphan receptor A, paralog a / RORA* / P51448* / P35398* / RAR related orphan receptor A* / RAR-related orphan receptor alpha*ENSDARG0000003176821
rorca / RAR-related orphan receptor C aENSDARG0000005723120
rorcb / RAR-related orphan receptor C bENSDARG0000001778020
ppardb / peroxisome proliferator-activated receptor delta b / PPARD* / P35396* / Q03181* / peroxisome proliferator activated receptor delta*ENSDARG0000000947319
pparda / peroxisome proliferator-activated receptor delta a / PPARD* / P35396* / Q03181* / peroxisome proliferator activated receptor delta*ENSDARG0000004452519
nr5a2 / nuclear receptor subfamily 5, group A, member 2 / O00482*ENSDARG0000010094017
nr5a5 / nuclear receptor subfamily 5, group A, member 5ENSDARG0000003911617
nr5a1a / nuclear receptor subfamily 5, group A, member 1a / NR5A1* / P33242* / Q13285* / Steroidogenic factor 1 * / nuclear receptor subfamily 5 group A member 1*ENSDARG0000010317616
nr5a1b / nuclear receptor subfamily 5, group A, member 1b / NR5A1* / P33242* / Q13285* / Steroidogenic factor 1 * / nuclear receptor subfamily 5 group A member 1*ENSDARG0000002336216
nr6a1a / nuclear receptor subfamily 6, group A, member 1a / NR6A1* / Q64249* / Q15406* / nuclear receptor subfamily 6 group A member 1*ENSDARG0000010150816
nr6a1b / nuclear receptor subfamily 6, group A, member 1bENSDARG0000001448015
rorc / RAR-related orphan receptor C / P51449* / P51450* / Nuclear receptor ROR-gamma *ENSDARG0000008719510


Protein motifs (from Interpro)
Interpro ID Name
 IPR000536  Nuclear hormone receptor, ligand-binding domain
 IPR001628  Zinc finger, nuclear hormone receptor-type
 IPR001723  Nuclear hormone receptor
 IPR001728  Thyroid hormone receptor
 IPR013088  Zinc finger, NHR/GATA-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006914 autophagy IMP
 biological_processGO:0010468 regulation of gene expression IGI
 biological_processGO:0030522 intracellular receptor signaling pathway IEA
 biological_processGO:0032922 circadian regulation of gene expression IMP
 biological_processGO:0043401 steroid hormone mediated signaling pathway IEA
 biological_processGO:1904059 regulation of locomotor rhythm IMP
 cellular_componentGO:0000785 chromatin IDA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IMP
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0003707 steroid hormone receptor activity IEA
 molecular_functionGO:0004887 thyroid hormone receptor activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IDA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Nuclear Receptor transcription pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain increased amount , abnormal
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 ZFA:0000029 hindbrain hindbrain autolysosome increased amount , abnormal
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 ZFA:0000037 anatomical structure anatomical structure increased amount , abnormal
anatomical structure decreased amount , abnormal
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 ZFA:0000107 eye eye increased amount , abnormal
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 ZFA:0000114 heart heart decreased amount , abnormal
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 ZFA:0000123 liver liver increased amount , abnormal
liver autophagosome increased amount , abnormal
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 ZFA:0001338 intestine intestine decreased amount , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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