ENSMUSG00000020889


Mus musculus

Features
Gene ID: ENSMUSG00000020889
  
Biological name :Nr1d1
  
Synonyms : Nr1d1 / Nuclear receptor subfamily 1 group D member 1 / Q3UV55
  
Possible biological names infered from orthology : P20393
  
Species: Mus musculus
  
Chr. number: 11
Strand: -1
Band: D
Gene start: 98767932
Gene end: 98775333
  
Corresponding Affymetrix probe sets: 10390691 (MoGene1.0st)   1426464_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000069505
NCBI entrez gene - 217166     See in Manteia.
MGI - MGI:2444210
RefSeq - NM_145434
RefSeq Peptide - NP_663409
swissprot - Q3UV55
Ensembl - ENSMUSG00000020889
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nr1d1ENSDARG00000033160Danio rerio
 NR1D1ENSG00000126368Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Nr1d2 / Q60674 / nuclear receptor subfamily 1, group D, member 2 / Q14995*ENSMUSG0000002177549
Rora / P51448 / RAR-related orphan receptor alpha / P35398* / RAR related orphan receptor A*ENSMUSG0000003223822
Rorc / P51450 / Nuclear receptor ROR-gamma / P51449* / RAR related orphan receptor C*ENSMUSG0000002815022
Ppara / P23204 / peroxisome proliferator activated receptor alpha / Q07869*ENSMUSG0000002238321
Ppard / P35396 / Peroxisome proliferator-activated receptor delta / Q03181*ENSMUSG0000000225021
Rorb / Q8R1B8 / Nuclear receptor ROR-beta / Q92753* / RAR related orphan receptor B*ENSMUSG0000003619221
Pparg / peroxisome proliferator activated receptor gamma / P37231*ENSMUSG0000000044021
Nr5a2 / P45448 / Nuclear receptor subfamily 5 group A member 2 / O00482*ENSMUSG0000002639819
Nr6a1 / Q64249 / Nuclear receptor subfamily 6 group A member 1 / Q15406*ENSMUSG0000006397216
Nr5a1 / P33242 / Steroidogenic factor 1 / Q13285* / nuclear receptor subfamily 5 group A member 1*ENSMUSG0000002675115


Protein motifs (from Interpro)
Interpro ID Name
 IPR000536  Nuclear hormone receptor, ligand-binding domain
 IPR001628  Zinc finger, nuclear hormone receptor-type
 IPR001723  Nuclear hormone receptor
 IPR013088  Zinc finger, NHR/GATA-type
 IPR035500  Nuclear hormone receptor-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0005978 glycogen biosynthetic process IMP
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IDA
 biological_processGO:0007623 circadian rhythm TAS
 biological_processGO:0010498 proteasomal protein catabolic process IDA
 biological_processGO:0010871 negative regulation of receptor biosynthetic process IEA
 biological_processGO:0019216 regulation of lipid metabolic process IMP
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0032922 circadian regulation of gene expression IMP
 biological_processGO:0034144 negative regulation of toll-like receptor 4 signaling pathway IEA
 biological_processGO:0035947 regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter IEA
 biological_processGO:0042752 regulation of circadian rhythm IMP
 biological_processGO:0043401 steroid hormone mediated signaling pathway IEA
 biological_processGO:0044321 response to leptin IDA
 biological_processGO:0045598 regulation of fat cell differentiation IMP
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IMP
 biological_processGO:0048511 rhythmic process IEA
 biological_processGO:0060086 circadian temperature homeostasis IMP
 biological_processGO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus IMP
 biological_processGO:0061469 regulation of type B pancreatic cell proliferation IMP
 biological_processGO:0070859 positive regulation of bile acid biosynthetic process IMP
 biological_processGO:0071222 cellular response to lipopolysaccharide IEA
 cellular_componentGO:0000790 nuclear chromatin IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0016604 nuclear body IEA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043197 dendritic spine IEA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001046 core promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001222 transcription corepressor binding IEA
 molecular_functionGO:0003677 DNA binding IDA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IDA
 molecular_functionGO:0003707 steroid hormone receptor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0020037 heme binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Nuclear Receptor transcription pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000182 increased circulating LDL cholesterol level "greater than average concentration in the blood of low density lipoprotein, which normally transports cholesterol to tissues other than the liver" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: St14tm2Bug/St14tm3Bug,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * Black Swiss * C57BL/6 * CBA

 MP:0000274 enlarged heart "increase over normal size of the heart" [J:29971]
Show

Allelic Composition: Npc1tm1b(EUCOMM)Hmgu/Npc1+
Genetic Background: C57BL/6N-Npc1tm1b(EUCOMM)Hmgu/H

 MP:0000280 thin ventricular wall "decreased depth of the cardiac wall of the heart ventricles" [J:45302]
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Allelic Composition: Npc1tm1b(EUCOMM)Hmgu/Npc1+
Genetic Background: C57BL/6N-Npc1tm1b(EUCOMM)Hmgu/H

 MP:0000849 abnormal cerebellum morphology "any malformation or absence of the part of the metencephalon that lies in the posterior cranial fossa dorsal to the pons and medulla that is concerned with the coordination of movement and learning of motor skills" [J:50311, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]
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Allelic Composition: Fabp4tm1Brsp/Fabp4tm1Brsp,Fabp5tm1Hota/Fabp5tm1Hota
Genetic Background: B6.Cg-Fabp4tm1Brsp Fabp5tm1Hota

 MP:0000854 abnormal cerebellum development "malformed or incomplete differentiation of the part of the metencephalon that lies dorsal to the pons and medulla behind the brain stem and controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Fabp4tm1Brsp/Fabp4tm1Brsp,Fabp5tm1Hota/Fabp5tm1Hota
Genetic Background: B6.Cg-Fabp4tm1Brsp Fabp5tm1Hota

 MP:0000872 abnormal external granule cell layer "malformation of the transient layer of the cerebellar cortex which is composed of the dividing and migrating granule cells" [tc:Teresa Chu , Mouse Genome Informatics Curator]
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Allelic Composition: Fabp4tm1Brsp/Fabp4tm1Brsp,Fabp5tm1Hota/Fabp5tm1Hota
Genetic Background: B6.Cg-Fabp4tm1Brsp Fabp5tm1Hota

 MP:0000889 abnormal cerebellar molecular layer "any malformation or absence of the outermost layer of the cerebral cortex that contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:38857]
Show

Allelic Composition: Fabp4tm1Brsp/Fabp4tm1Brsp,Fabp5tm1Hota/Fabp5tm1Hota
Genetic Background: B6.Cg-Fabp4tm1Brsp Fabp5tm1Hota

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
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Allelic Composition: Fabp4tm1Brsp/Fabp4tm1Brsp,Fabp5tm1Hota/Fabp5tm1Hota
Genetic Background: B6.Cg-Fabp4tm1Brsp Fabp5tm1Hota

 MP:0001539 decreased number of caudal vertebrae "reduced number of the bony segments of the tail" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Npc1tm1b(EUCOMM)Hmgu/Npc1+
Genetic Background: C57BL/6N-Npc1tm1b(EUCOMM)Hmgu/H

 MP:0001554 increased circulating free fatty acid level "higher than normal levels of unesterified fatty acids in the blood" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:65146]
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Allelic Composition: Nr1d1tm1.2Rev/Nr1d1tm1.2Rev
Genetic Background: involves: BALB/cJ * C57BL/6J

 MP:0001556 increased circulating HDL cholesterol level "higher than average level of high density lipoprotein in the blood; this molecule transports cholesterol to the liver for excretion in bile" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:47439]
Show

Allelic Composition: St14tm2Bug/St14tm3Bug,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * Black Swiss * C57BL/6 * CBA

 MP:0001922 reduced male fertility "reduced ability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61340]
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Allelic Composition: Nr1d1tm1.2Rev/Nr1d1tm1.2Rev
Genetic Background: involves: BALB/cJ * C57BL/6J

 MP:0001923 reduced female fertility "reduced ability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
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Allelic Composition: Fabp4tm1Brsp/Fabp4tm1Brsp,Fabp5tm1Hota/Fabp5tm1Hota
Genetic Background: B6.Cg-Fabp4tm1Brsp Fabp5tm1Hota

Allelic Composition: Nr1d1tm1.2Rev/Nr1d1tm1.2Rev
Genetic Background: involves: BALB/cJ * C57BL/6J

 MP:0001935 reduced litter size "fewer live born pups in a litter compared to average" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Lyntm1Sor/Lyntm1Sor
Genetic Background: involves: 129S4/SvJaeSor

 MP:0002092 abnormal eye morphology "abnormal development of the eye tissues resulting in morphological abnormality or abnormal structure of the visual system" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Npc1tm1b(EUCOMM)Hmgu/Npc1+
Genetic Background: C57BL/6N-Npc1tm1b(EUCOMM)Hmgu/H

 MP:0002644 decreased circulating triglyceride level "lower than normal concentration of triacylglycerols in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Nr1d1tm1.2Rev/Nr1d1tm1.2Rev
Genetic Background: involves: BALB/cJ * C57BL/6J

 MP:0002757 reduced vertical activity "lesser than average time spent jumping or rearing" [J:82829, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Npc1tm1b(EUCOMM)Hmgu/Npc1+
Genetic Background: C57BL/6N-Npc1tm1b(EUCOMM)Hmgu/H

 MP:0003393 decreased cardiac output "reduction in the blood volume pumped by each ventricle per minute" [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Npc1tm1b(EUCOMM)Hmgu/Npc1+
Genetic Background: C57BL/6N-Npc1tm1b(EUCOMM)Hmgu/H

 MP:0003795 abnormal bone structure 
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Allelic Composition: Npc1tm1b(EUCOMM)Hmgu/Npc1+
Genetic Background: C57BL/6N-Npc1tm1b(EUCOMM)Hmgu/H

 MP:0004098 abnormal granule neuron "any structural anomaly of the small neurons of the granule cell layer that send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites" [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]
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Allelic Composition: Fabp4tm1Brsp/Fabp4tm1Brsp,Fabp5tm1Hota/Fabp5tm1Hota
Genetic Background: B6.Cg-Fabp4tm1Brsp Fabp5tm1Hota

 MP:0004924 abnormal behavior "anomalies in the actions, reactions, or performance of an organism in response to external or internal stimuli compared to controls" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Npc1tm1b(EUCOMM)Hmgu/Npc1+
Genetic Background: C57BL/6N-Npc1tm1b(EUCOMM)Hmgu/H

 MP:0005289 increased oxygen consumption "greater than the normal rate at which oxygen enters the blood from alveolar gas; this is equal in the steady state to the consumption of oxygen by tissue metabolism throughout the body" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Commd10Tg(Vav1-icre)A2Kio/?,Tnfrsf14tm1.1Kro/Tnfrsf14tm1.1Kro
Genetic Background: involves: C57BL/6NCrl * C57BL/10 * CBA * SJL

 MP:0005365 abnormal bile salt homeostasis "anomalous regulation of the steroid salts derived from cholesterol in the liver and which play an important role in the digestion and absorption of fats" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:86154]
Show

Allelic Composition: St14tm2Bug/St14tm3Bug,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * Black Swiss * C57BL/6 * CBA

 MP:0005533 increased body temperature "greater than the level of heat natural to a living being" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8, RGD:Rat Genome Database submission]
Show

Allelic Composition: Commd10Tg(Vav1-icre)A2Kio/?,Tnfrsf14tm1.1Kro/Tnfrsf14tm1.1Kro
Genetic Background: involves: C57BL/6NCrl * C57BL/10 * CBA * SJL

 MP:0005560 decreased circulating glucose level "less than the normal concentration in the blood of this major monosaccharide of the body; it is an important energy source" [RGD:Rat Genome Database submission, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Nr1d1tm1.2Rev/Nr1d1tm1.2Rev
Genetic Background: involves: BALB/cJ * C57BL/6J

 MP:0008572 abnormal Purkinje cell dendrite morphology "any strucutral anomaly of the Purkinje cell body projections with hundreds of parallel spiny branches reaching up into the molecular layer" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Fabp4tm1Brsp/Fabp4tm1Brsp,Fabp5tm1Hota/Fabp5tm1Hota
Genetic Background: B6.Cg-Fabp4tm1Brsp Fabp5tm1Hota

 MP:0008579 abnormal Purkinje cell differentiation "atypical production of or inability to produce the neurons located at the interface of the molecular and internal granule layers of the cerebellar cortex" [ISBN:0838580343 "Kandel ER, et al. Principles of Neural Science, 3rd edition"]
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Allelic Composition: Fabp4tm1Brsp/Fabp4tm1Brsp,Fabp5tm1Hota/Fabp5tm1Hota
Genetic Background: B6.Cg-Fabp4tm1Brsp Fabp5tm1Hota

 MP:0009356 decreased liver triglyceride level "lower than normal concentration of triacylglycerols in the liver" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: St14tm2Bug/St14tm3Bug,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * Black Swiss * C57BL/6 * CBA

 MP:0009399 increased skeletal muscle fiber size "increase in the size of the large multinucleated cells that make up the skeletal muscles" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Fabp4tm1Brsp/Fabp4tm1Brsp,Fabp5tm1Hota/Fabp5tm1Hota
Genetic Background: B6.Cg-Fabp4tm1Brsp Fabp5tm1Hota

 MP:0009409 abnormal skeletal muscle fiber type ratio "deviation from the standard ratios of fiber types in a given skeletal muscle compared to control samples" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Fabp4tm1Brsp/Fabp4tm1Brsp,Fabp5tm1Hota/Fabp5tm1Hota
Genetic Background: B6.Cg-Fabp4tm1Brsp Fabp5tm1Hota

 MP:0009764 decreased sensitivity to induced morbidity/mortality "increase in the amount of an external agent required to cause death or diseased state" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Commd10Tg(Vav1-icre)A2Kio/?,Tnfrsf14tm1.1Kro/Tnfrsf14tm1.1Kro
Genetic Background: involves: C57BL/6NCrl * C57BL/10 * CBA * SJL

 MP:0010025 decreased total body fat amount "less than the normal total amount of connective tissue composed of fat cells within the entire body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Npc1tm1b(EUCOMM)Hmgu/Npc1+
Genetic Background: C57BL/6N-Npc1tm1b(EUCOMM)Hmgu/H

 MP:0010026 decreased liver cholesterol level "less than normal amount in the liver of the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones; it is a component of the plasma membrane lipid bilayer and of plasma lipoproteins and can be found in all animal tissues" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: St14tm2Bug/St14tm3Bug,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * Black Swiss * C57BL/6 * CBA

 MP:0010123 increased bone mineral content "elevation in the amount (usually in grams/cm) of bone mineral divided by a bone-scanned area" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Npc1tm1b(EUCOMM)Hmgu/Npc1+
Genetic Background: C57BL/6N-Npc1tm1b(EUCOMM)Hmgu/H

 MP:0010379 decreased respiratory quotient "reduction in the ratio of the volume of carbon dioxide released to oxygen consumed by a body tissue or an organism compared to controls" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Nr1d1tm1.2Rev/Nr1d1tm1.2Rev
Genetic Background: involves: BALB/cJ * C57BL/6J

 MP:0011016 increased core body temperature "increased degree of heat natural to the internal center of a living being" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Commd10Tg(Vav1-icre)A2Kio/?,Tnfrsf14tm1.1Kro/Tnfrsf14tm1.1Kro
Genetic Background: involves: C57BL/6NCrl * C57BL/10 * CBA * SJL

 MP:0011020 abnormal circadian temperature homeostasis "any anomaly in the process in which an organism modulates its internal body temperature at different values with a regularity of approximately 24 hours" [GO:0060086]
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Allelic Composition: Commd10Tg(Vav1-icre)A2Kio/?,Tnfrsf14tm1.1Kro/Tnfrsf14tm1.1Kro
Genetic Background: involves: C57BL/6NCrl * C57BL/10 * CBA * SJL

 MP:0011086 partial postnatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
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Allelic Composition: Nr1d1tm1.2Rev/Nr1d1tm1.2Rev
Genetic Background: involves: BALB/cJ * C57BL/6J

 MP:0011110 partial preweaning lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Nampttm1.1(KOMP)Vlcg/Nampttm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Nampttm1.1(KOMP)Vlcg/Ucd

 MP:0011959 abnormal eye posterior chamber depth "anomaly in the distance between the iris and the lens at the center plane (maximum distance) of the posterior chamber, compared to controls" [MGI:csmith]
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Allelic Composition: Npc1tm1b(EUCOMM)Hmgu/Npc1+
Genetic Background: C57BL/6N-Npc1tm1b(EUCOMM)Hmgu/H

 MP:0020468 abnormal circadian behavior period "any change in the cycle length of a behavior expressed when exposed to constant conditions without temporal cues" [MGI:smb]
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Allelic Composition: Fbxl3tm1.1Ljp/Fbxl3tm1.1Ljp
Genetic Background: Not Specified

 MP:0020470 shortened circadian behavior period "decrease in the cycle length of a behavior expressed when exposed to constant conditions without temporal cues" [MGI:smb]
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Allelic Composition: Lyntm1Sor/Lyntm1Sor
Genetic Background: involves: 129S4/SvJaeSor

Allelic Composition: Nr1d1tm1.2Rev/Nr1d1tm1.2Rev
Genetic Background: involves: BALB/cJ * C57BL/6J

Allelic Composition: Nr1d1tm1.1Rev/Nr1d1tm1.1Rev,Nr1d2tm1.1Rev/Nr1d2tm1.1Rev,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: BALB/cJ * C57BL/6 * C57BL/6J * CBA

 MP:0020474 advanced circadian behavior phase "increase in the phase relationship between a temporal synchronizing event (such as light cycle) and a behavioral phase reference point of an animal (such as activity onset)" [MGI:smb]
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Allelic Composition: Lyntm1Sor/Lyntm1Sor
Genetic Background: involves: 129S4/SvJaeSor

 MP:0020523 decreased susceptibility to induced hypothermia "smaller than expected drop in body temperature in response to treatment (cold-exposure, dietary restriction, ethanol treatment, etc..) designed to induce hypothermia" [MGI:mperry, PMID:24531262]
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Allelic Composition: Commd10Tg(Vav1-icre)A2Kio/?,Tnfrsf14tm1.1Kro/Tnfrsf14tm1.1Kro
Genetic Background: involves: C57BL/6NCrl * C57BL/10 * CBA * SJL

 MP:0030016 increased adipocyte glucose uptake "increased ability of adipocytes to take in glucose" [MGI:anna]
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Allelic Composition: Commd10Tg(Vav1-icre)A2Kio/?,Tnfrsf14tm1.1Kro/Tnfrsf14tm1.1Kro
Genetic Background: involves: C57BL/6NCrl * C57BL/10 * CBA * SJL

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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