ENSDARG00000054323


Danio rerio

Features
Gene ID: ENSDARG00000054323
  
Biological name :pparab
  
Synonyms : peroxisome proliferator-activated receptor alpha b / pparab
  
Possible biological names infered from orthology : P23204 / peroxisome proliferator activated receptor alpha / PPARA / Q07869
  
Species: Danio rerio
  
Chr. number: 25
Strand: 1
Band:
Gene start: 2198781
Gene end: 2254112
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000126384
Ensembl peptide - ENSDARP00000156861
NCBI entrez gene - 557714     See in Manteia.
RefSeq - NM_001102567
RefSeq Peptide - NP_001096037
swissprot - K7DY57
ZFIN ID - ZDB-GENE-990415-211
Ensembl - ENSDARG00000054323
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PPARAENSGALG00000041470Gallus gallus
 PPARAENSG00000186951Homo sapiens
 PparaENSMUSG00000022383Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
pparaa / peroxisome proliferator-activated receptor alpha a / PPARA* / P23204* / Q07869* / peroxisome proliferator activated receptor alpha*ENSDARG0000003177772
pparda / peroxisome proliferator-activated receptor delta a / PPARD* / P35396* / Q03181* / peroxisome proliferator activated receptor delta*ENSDARG0000004452559
ppardb / peroxisome proliferator-activated receptor delta b / PPARD* / P35396* / Q03181* / peroxisome proliferator activated receptor delta*ENSDARG0000000947358
nr1d1 / nuclear receptor subfamily 1, group d, member 1 / P20393* / Q3UV55*ENSDARG0000003316029
nr1d2b / nuclear receptor subfamily 1, group D, member 2b / NR1D2* / Q60674* / Q14995* / nuclear receptor subfamily 1 group D member 2*ENSDARG0000000959428
nr1d4b / nuclear receptor subfamily 1, group D, member 4bENSDARG0000005937028
nr1d4a / nuclear receptor subfamily 1, group D, member 4aENSDARG0000003116128
nr1d2a / nuclear receptor subfamily 1, group D, member 2aENSDARG0000000382026
rorab / RAR-related orphan receptor A, paralog bENSDARG0000000191024
rorb / RAR-related orphan receptor B / Q8R1B8* / Q92753* / Nuclear receptor ROR-beta *ENSDARG0000003349822
rorcb / RAR-related orphan receptor C bENSDARG0000001778022
roraa / RAR-related orphan receptor A, paralog a / RORA* / P51448* / P35398* / RAR related orphan receptor A* / RAR-related orphan receptor alpha*ENSDARG0000003176822
rorca / RAR-related orphan receptor C aENSDARG0000005723122
nr5a2 / nuclear receptor subfamily 5, group A, member 2 / O00482*ENSDARG0000010094020
nr5a5 / nuclear receptor subfamily 5, group A, member 5ENSDARG0000003911620
nr5a1a / nuclear receptor subfamily 5, group A, member 1a / NR5A1* / P33242* / Q13285* / Steroidogenic factor 1 * / nuclear receptor subfamily 5 group A member 1*ENSDARG0000010317619
nr6a1a / nuclear receptor subfamily 6, group A, member 1a / NR6A1* / Q64249* / Q15406* / nuclear receptor subfamily 6 group A member 1*ENSDARG0000010150819
nr5a1b / nuclear receptor subfamily 5, group A, member 1b / NR5A1* / P33242* / Q13285* / Steroidogenic factor 1 * / nuclear receptor subfamily 5 group A member 1*ENSDARG0000002336219
nr6a1b / nuclear receptor subfamily 6, group A, member 1bENSDARG0000001448017
rorc / RAR-related orphan receptor C / P51449* / P51450* / Nuclear receptor ROR-gamma *ENSDARG0000008719512


Protein motifs (from Interpro)
Interpro ID Name
 IPR000536  Nuclear hormone receptor, ligand-binding domain
 IPR001628  Zinc finger, nuclear hormone receptor-type
 IPR001723  Nuclear hormone receptor
 IPR003074  Peroxisome proliferator-activated receptor
 IPR003076  Peroxisome proliferator-activated receptor alpha
 IPR013088  Zinc finger, NHR/GATA-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0014823 response to activity IDA
 biological_processGO:0030522 intracellular receptor signaling pathway IEA
 biological_processGO:0043401 steroid hormone mediated signaling pathway IEA
 biological_processGO:0070417 cellular response to cold IDA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0003707 steroid hormone receptor activity IEA
 molecular_functionGO:0004879 nuclear receptor activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Nuclear Receptor transcription pathway
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
SUMOylation of intracellular receptors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000019357 Q1AMT3 / fabp1a / fatty acid binding protein 1a, liver / FABP1* / P07148* / fatty acid binding protein 1*  / reaction
 ENSDARG00000007438 ube2ib / Q9W6H5 / ubiquitin-conjugating enzyme E2Ib / UBE2I* / P63279* / ubiquitin conjugating enzyme E2 I*  / reaction
 ENSDARG00000044267 sumo1 / Q7SZR5 / small ubiquitin-like modifier 1 / P63166* / P63165* / Small ubiquitin-related modifier 1 *  / reaction / complex
 ENSDARG00000052649 Q9DDJ0 / ube2ia / ubiquitin-conjugating enzyme E2Ia / UBE2I* / P63280* / P63279* / ubiquitin conjugating enzyme E2 I*  / reaction
 ENSDARG00000060438 tbl1x / transducin beta like 1 X-linked / TBL1Y* / Q9QXE7* / O60907* / Q9BQ87* / transducin beta like 1 Y-linked* / F-box-like/WD repeat-containing protein TBL1X *  / reaction / complex
 ENSDARG00000059227 Q4VBT1 / fabp1b.1 / fatty acid binding protein 1b, tandem duplicate 1 / FABP1* / P07148* / P12710* / fatty acid binding protein 1* / Fatty acid-binding protein, liver *  / reaction
 ENSDARG00000058696 tbl1xr1a / transducin (beta)-like 1 X-linked receptor 1a / Q9BZK7* / Q8BHJ5* / TBL1XR1* / transducin beta like 1 X-linked receptor 1* / F-box-like/WD repeat-containing protein TBL1XR1 *  / reaction / complex
 ENSDARG00000057737 rxraa / retinoid X receptor, alpha a / RXRA* / P19793* / P28700* / retinoid X receptor alpha*  / reaction / complex
 ENSDARG00000008966 tbl1xr1b / transducin (beta)-like 1 X-linked receptor 1b / Q9BZK7* / Q8BHJ5* / TBL1XR1* / transducin beta like 1 X-linked receptor 1* / F-box-like/WD repeat-containing protein TBL1XR1 *  / reaction / complex
 ENSDARG00000103398 fabp1b.2 / fatty acid binding protein 1b, liver, tandem duplicate 2 / FABP1* / P07148* / P12710* / fatty acid binding protein 1* / Fatty acid-binding protein, liver *  / reaction






 

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