ENSDARG00000036685


Danio rerio

Features
Gene ID: ENSDARG00000036685
  
Biological name :ccnt2a
  
Synonyms : ccnt2a / cyclin T2a
  
Possible biological names infered from orthology : CCNT2 / cyclin T2 / O60583 / Q7TQK0
  
Species: Danio rerio
  
Chr. number: 9
Strand: -1
Band:
Gene start: 23234233
Gene end: 23242684
  
Corresponding Affymetrix probe sets: Dr.7339.1.S1_at (Zebrafish Array)   NM_199828_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000053281
Ensembl peptide - ENSDARP00000151430
NCBI entrez gene - 327568     See in Manteia.
RefSeq - NM_199828
RefSeq - NM_001193381
RefSeq Peptide - NP_001180310
RefSeq Peptide - NP_956122
swissprot - Q803Q8
ZFIN ID - ZDB-GENE-030131-5779
Ensembl - ENSDARG00000036685
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CCNT2ENSGALG00000012207Gallus gallus
 CCNT2ENSG00000082258Homo sapiens
 Ccnt2ENSMUSG00000026349Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ccnt2b / cyclin T2bENSDARG0000003651055
ccnt1 / cyclin T1 / O60563* / Q9QWV9*ENSDARG0000001752544
ccnk / cyclin K / O75909*ENSDARG0000003414617
ccnl1a / cyclin L1a / CCNL1* / Q52KE7* / Q9UK58* / cyclin L1* / Mus musculus cyclin L1 (Ccnl1), transcript variant 2, mRNA.*ENSDARG0000005512417
ccnl1b / cyclin L1b / CCNL1* / Q52KE7* / Q9UK58* / cyclin L1* / Mus musculus cyclin L1 (Ccnl1), transcript variant 2, mRNA.*ENSDARG0000001214014
ccnc / cyclin C / P24863* / Q62447*ENSDARG0000000960711
ccnq / cyclin Q / Fam58b* / Q8QZR8* / Q8N1B3* / family with sequence similarity 58, member B*ENSDARG000000375379


Protein motifs (from Interpro)
Interpro ID Name
 IPR006671  Cyclin, N-terminal
 IPR013763  Cyclin-like
 IPR028862  Cyclin-T2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity IBA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IBA
 biological_processGO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain IBA
 cellular_componentGO:0000307 cyclin-dependent protein kinase holoenzyme complex IBA
 cellular_componentGO:0005634 nucleus IBA
 molecular_functionGO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity IBA


Pathways (from Reactome)
Pathway description
Formation of RNA Pol II elongation complex
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
RNA Polymerase II Pre-transcription Events
TP53 Regulates Transcription of DNA Repair Genes
RNA polymerase II transcribes snRNA genes
RNA Polymerase II Transcription Elongation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000075226 smad4a / SMAD family member 4a / SMAD4* / Q13485* / SMAD family member 4*  / reaction
 ENSDARG00000036096 smad3a / SMAD family member 3a / SMAD3* / Q8BUN5* / P84022* / SMAD family member 3* / Mothers against decapentaplegic homolog 3 *  / reaction
 ENSDARG00000006389 smad2 / Q9I9P9 / SMAD family member 2 / Q62432* / Q15796* / Mothers against decapentaplegic homolog 2 *  / reaction
 ENSDARG00000044811 cdk9 / cyclin-dependent kinase 9 (CDC2-related kinase) / P50750* / Q99J95* / cyclin dependent kinase 9*  / reaction / complex






 

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