ENSDARG00000045359


Danio rerio

Features
Gene ID: ENSDARG00000045359
  
Biological name :elocb
  
Synonyms : elocb / elongin C paralog b
  
Possible biological names infered from orthology : ELOC / elongin C / P83940 / Q15369
  
Species: Danio rerio
  
Chr. number: 2
Strand: -1
Band:
Gene start: 30244376
Gene end: 30250311
  
Corresponding Affymetrix probe sets: Dr.5707.1.S1_at (Zebrafish Array)   NM_001002440_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000144253
Ensembl peptide - ENSDARP00000153381
Ensembl peptide - ENSDARP00000107171
Ensembl peptide - ENSDARP00000118581
NCBI entrez gene - 436713     See in Manteia.
RefSeq - NM_001002440
RefSeq Peptide - NP_001002440
swissprot - A0A286YBA4
swissprot - Q502M9
swissprot - Q6DH59
ZFIN ID - ZDB-GENE-040718-138
Ensembl - ENSDARG00000045359
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ELOCENSGALG00000035417Gallus gallus
 ELOCENSG00000154582Homo sapiens
 ElocENSMUSG00000079658Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
eloca / elongin C paralog aENSDARG0000004535596


Protein motifs (from Interpro)
Interpro ID Name
 IPR001232  S-phase kinase-associated protein 1-like
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR016073  SKP1 component, POZ domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter IBA
 cellular_componentGO:0070449 elongin complex IBA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IBA


Pathways (from Reactome)
Pathway description
Formation of RNA Pol II elongation complex
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
RNA Polymerase II Pre-transcription Events
TP53 Regulates Transcription of DNA Repair Genes
RNA Polymerase II Transcription Elongation
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000008697 epas1a / endothelial PAS domain protein 1a / EPAS1* / Q99814* / P97481* / endothelial PAS domain protein 1* / Endothelial PAS domain-containing protein 1 *  / complex / reaction
 ENSDARG00000034293 hif1ab / hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) b / HIF1A* / Q61221* / Q16665* / Hypoxia-inducible factor 1-alpha * / hypoxia inducible fact...  / complex / reaction
 ENSDARG00000038576 ube2d1b / ubiquitin-conjugating enzyme E2D 1b / UBE2D1* / P51668* / P61080* / ubiquitin conjugating enzyme E2 D1*  / reaction
 ENSDARG00000006181 hif1aa / hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) a / HIF1A* / Q61221* / Q16665* / Hypoxia-inducible factor 1-alpha * / hypoxia inducible fact...  / reaction / complex
 ENSDARG00000043484 ube2d2 / ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) / P62838* / P62837* / Ube2d2a* / ubiquitin conjugating enzyme E2 D2* / ubiquitin-conjugating enzyme E2D 2A*  / reaction
 ENSDARG00000038030 rbx1 / ring-box 1, E3 ubiquitin protein ligase / P62878* / P62877* / ring-box 1* / E3 ubiquitin-protein ligase RBX1 E3 ubiquitin-protein ligase RBX1, N-terminally processed*  / complex
 ENSDARG00000057671 epas1b / endothelial PAS domain protein 1b / EPAS1* / Q99814* / P97481* / endothelial PAS domain protein 1* / Endothelial PAS domain-containing protein 1 *  / complex / reaction
 ENSDARG00000025428 socs3a / suppressor of cytokine signaling 3a / SOCS3* / O14543* / suppressor of cytokine signaling 3*  / complex
 ENSDARG00000038095 socs1a / suppressor of cytokine signaling 1a / SOCS1* / O35716* / O15524* / suppressor of cytokine signaling 1*  / complex
 ENSDARG00000096306 si:ch1073-342h5.2 / LRRC41* / Q15345* / Q8K1C9* / leucine rich repeat containing 41* / Leucine-rich repeat-containing protein 41 *  / complex
 ENSDARG00000037980 elob / elongin B / Elobl* / P62869* / Q15370*  / complex / reaction
 ENSDARG00000038996 egln1a / egl-9 family hypoxia-inducible factor 1a / EGLN1* / Q91YE3* / Q9GZT9* / Egl nine homolog 1 * / egl-9 family hypoxia inducible factor 1*  / complex
 ENSDARG00000004260 cul5b / cullin 5b / CUL5* / Q93034* / cullin 5*  / complex
 ENSDARG00000004632 egln1b / egl-9 family hypoxia-inducible factor 1b / EGLN1* / Q91YE3* / Q9GZT9* / Egl nine homolog 1 * / egl-9 family hypoxia inducible factor 1*  / complex
 ENSDARG00000026611 socs3b / suppressor of cytokine signaling 3b / SOCS3* / O35718* / O14543* / suppressor of cytokine signaling 3*  / complex
 ENSDARG00000069742 cul5a / cullin 5a / CUL5* / Q93034* / cullin 5*  / complex
 ENSDARG00000100826 hif1al / hypoxia-inducible factor 1, alpha subunit, like / HIF3A* / Q9Y2N7* / Q0VBL6* / Hypoxia-inducible factor 3-alpha * / hypoxia inducible factor 3 alpha subunit*  / complex / reaction
 ENSDARG00000013965 cul2 / cullin 2 / Q13617* / Q9D4H8*  / complex






 

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