ENSMUSG00000079658


Mus musculus

Features
Gene ID: ENSMUSG00000079658
  
Biological name :Eloc
  
Synonyms : Eloc / Elongin-C / P83940
  
Possible biological names infered from orthology : Q15369
  
Species: Mus musculus
  
Chr. number: 1
Strand: -1
Band: A3
Gene start: 16641725
Gene end: 16657042
  
Corresponding Affymetrix probe sets: 10353296 (MoGene1.0st)   1427914_a_at (Mouse Genome 430 2.0 Array)   1427915_s_at (Mouse Genome 430 2.0 Array)   1436226_at (Mouse Genome 430 2.0 Array)   1452593_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000140161
Ensembl peptide - ENSMUSP00000139741
Ensembl peptide - ENSMUSP00000140422
Ensembl peptide - ENSMUSP00000140962
Ensembl peptide - ENSMUSP00000111009
Ensembl peptide - ENSMUSP00000139480
Ensembl peptide - ENSMUSP00000139675
NCBI entrez gene - 67923     See in Manteia.
MGI - MGI:1915173
RefSeq - XM_017322272
RefSeq - XM_006495559
RefSeq - XM_006495561
RefSeq - XM_006495562
RefSeq - XM_006495563
RefSeq - XM_006495564
RefSeq - XM_011238403
RefSeq - NM_001310470
RefSeq - NM_026456
RefSeq - XM_006495558
RefSeq Peptide - NP_001297399
RefSeq Peptide - NP_080732
swissprot - A0A087WQE6
swissprot - A0A087WPE4
swissprot - P83940
swissprot - A0A087WNT1
Ensembl - ENSMUSG00000079658
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 elocbENSDARG00000045359Danio rerio
 ELOCENSGALG00000035417Gallus gallus
 ELOCENSG00000154582Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001232  S-phase kinase-associated protein 1-like
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR016073  SKP1 component, POZ domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter IBA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0070449 elongin complex IDA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IBA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Formation of RNA Pol II elongation complex
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
RNA Polymerase II Pre-transcription Events
TP53 Regulates Transcription of DNA Repair Genes
RNA Polymerase II Transcription Elongation
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000019927 P61080 / Ube2d1 / ubiquitin-conjugating enzyme E2D 1 / P51668*  / reaction
 ENSMUSG00000024140 Epas1 / P97481 / Endothelial PAS domain-containing protein 1 / Q99814* / endothelial PAS domain protein 1*  / complex / reaction
 ENSMUSG00000024231 Cul2 / Q9D4H8 / Cullin-2 / Q13617*  / complex
 ENSMUSG00000021109 Hif1a / Q61221 / Hypoxia-inducible factor 1-alpha / Q16665* / hypoxia inducible factor 1 alpha subunit*  / complex / reaction
 ENSMUSG00000022400 Rbx1 / P62878 / E3 ubiquitin-protein ligase RBX1 E3 ubiquitin-protein ligase RBX1, N-terminally processed / P62877* / ring-box 1*  / complex
 ENSMUSG00000025239 Limd1 / Q9QXD8 / LIM domain-containing protein 1 / Q9UGP4* / LIM domains containing 1*  / complex
 ENSMUSG00000004328 Hif3a / Q0VBL6 / Hypoxia-inducible factor 3-alpha / Q9Y2N7* / hypoxia inducible factor 3 alpha subunit*  / complex / reaction
 ENSMUSG00000032030 Cul5 / cullin 5 / Q93034*  / complex
 ENSMUSG00000055839 Elob / P62869 / Elongin-B / Q15370*  / reaction / complex
 ENSMUSG00000078578 P61079 / Ube2d3 / ubiquitin-conjugating enzyme E2D 3 / P61077*  / reaction
 ENSMUSG00000033933 Vhl / P40338 / von Hippel-Lindau tumor suppressor / VHLL* / Q6RSH7* / P40337* / VHL like*  / complex
 ENSMUSG00000028668 Eloa / Q8CB77 / Elongin-A / Q14241*  / reaction / complex
 ENSMUSG00000053113 Socs3 / O35718 / suppressor of cytokine signaling 3 / O14543*  / complex
 ENSMUSG00000035105 Egln3 / egl-9 family hypoxia inducible factor 3 / Q9H6Z9*  / complex
 ENSMUSG00000031987 Egln1 / Q91YE3 / Egl nine homolog 1 / Q9GZT9* / egl-9 family hypoxia inducible factor 1*  / complex
 ENSMUSG00000038037 Socs1 / O35716 / Suppressor of cytokine signaling 1 / O15524*  / complex
 ENSMUSG00000028703 Lrrc41 / Q8K1C9 / Leucine-rich repeat-containing protein 41 / Q15345* / leucine rich repeat containing 41*  / complex
 ENSMUSG00000091896 P62838 / Ube2d2a / ubiquitin-conjugating enzyme E2D 2A / UBE2D2* / P62837* / ubiquitin conjugating enzyme E2 D2*  / reaction






 

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