ENSMUSG00000055839


Mus musculus

Features
Gene ID: ENSMUSG00000055839
  
Biological name :Elob
  
Synonyms : Elob / Elongin-B / P62869
  
Possible biological names infered from orthology : Q15370
  
Species: Mus musculus
  
Chr. number: 17
Strand: -1
Band: A3.3
Gene start: 23824740
Gene end: 23829109
  
Corresponding Affymetrix probe sets: 10448380 (MoGene1.0st)   10452890 (MoGene1.0st)   1428263_a_at (Mouse Genome 430 2.0 Array)   1436949_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000066210
NCBI entrez gene - 67673     See in Manteia.
MGI - MGI:1914923
RefSeq - NM_026305
RefSeq Peptide - NP_080581
swissprot - P62869
Ensembl - ENSMUSG00000055839
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 elobENSDARG00000037980Danio rerio
 elongin BENSDARG00000097471Danio rerio
 ELOBENSG00000103363Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
EloblENSMUSG0000005753465


Protein motifs (from Interpro)
Interpro ID Name
 IPR000626  Ubiquitin domain
 IPR029071  Ubiquitin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005667 transcription factor complex IEA
 cellular_componentGO:0030891 VCB complex IEA
 cellular_componentGO:0031462 Cul2-RING ubiquitin ligase complex IEA
 cellular_componentGO:0031466 Cul5-RING ubiquitin ligase complex IEA
 cellular_componentGO:0070449 elongin complex IDA
 molecular_functionGO:0003713 transcription coactivator activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0031625 ubiquitin protein ligase binding IEA


Pathways (from Reactome)
Pathway description
Formation of RNA Pol II elongation complex
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
RNA Polymerase II Pre-transcription Events
TP53 Regulates Transcription of DNA Repair Genes
RNA Polymerase II Transcription Elongation
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000019927 P61080 / Ube2d1 / ubiquitin-conjugating enzyme E2D 1 / P51668*  / reaction
 ENSMUSG00000024140 Epas1 / P97481 / Endothelial PAS domain-containing protein 1 / Q99814* / endothelial PAS domain protein 1*  / complex / reaction
 ENSMUSG00000024231 Cul2 / Q9D4H8 / Cullin-2 / Q13617*  / complex
 ENSMUSG00000021109 Hif1a / Q61221 / Hypoxia-inducible factor 1-alpha / Q16665* / hypoxia inducible factor 1 alpha subunit*  / complex / reaction
 ENSMUSG00000022400 Rbx1 / P62878 / E3 ubiquitin-protein ligase RBX1 E3 ubiquitin-protein ligase RBX1, N-terminally processed / P62877* / ring-box 1*  / complex
 ENSMUSG00000025239 Limd1 / Q9QXD8 / LIM domain-containing protein 1 / Q9UGP4* / LIM domains containing 1*  / complex
 ENSMUSG00000004328 Hif3a / Q0VBL6 / Hypoxia-inducible factor 3-alpha / Q9Y2N7* / hypoxia inducible factor 3 alpha subunit*  / reaction / complex
 ENSMUSG00000032030 Cul5 / cullin 5 / Q93034*  / complex
 ENSMUSG00000028668 Eloa / Q8CB77 / Elongin-A / Q14241*  / reaction / complex
 ENSMUSG00000028703 Lrrc41 / Q8K1C9 / Leucine-rich repeat-containing protein 41 / Q15345* / leucine rich repeat containing 41*  / complex
 ENSMUSG00000031987 Egln1 / Q91YE3 / Egl nine homolog 1 / Q9GZT9* / egl-9 family hypoxia inducible factor 1*  / complex
 ENSMUSG00000038037 Socs1 / O35716 / Suppressor of cytokine signaling 1 / O15524*  / complex
 ENSMUSG00000079658 Eloc / P83940 / Elongin-C / Q15369*  / complex / reaction
 ENSMUSG00000053113 Socs3 / O35718 / suppressor of cytokine signaling 3 / O14543*  / complex
 ENSMUSG00000035105 Egln3 / egl-9 family hypoxia inducible factor 3 / Q9H6Z9*  / complex
 ENSMUSG00000033933 Vhl / P40338 / von Hippel-Lindau tumor suppressor / VHLL* / Q6RSH7* / P40337* / VHL like*  / complex
 ENSMUSG00000078578 P61079 / Ube2d3 / ubiquitin-conjugating enzyme E2D 3 / P61077*  / reaction
 ENSMUSG00000091896 P62838 / Ube2d2a / ubiquitin-conjugating enzyme E2D 2A / UBE2D2* / P62837* / ubiquitin conjugating enzyme E2 D2*  / reaction






 

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