ENSG00000080573


Homo sapiens

Features
Gene ID: ENSG00000080573
  
Biological name :COL5A3
  
Synonyms : COL5A3 / collagen type V alpha 3 chain / P25940
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: p13.2
Gene start: 9959561
Gene end: 10010471
  
Corresponding Affymetrix probe sets: 218975_at (Human Genome U133 Plus 2.0 Array)   52255_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000264828
NCBI entrez gene - 50509     See in Manteia.
OMIM - 120216
RefSeq - NM_015719
RefSeq - XM_011528042
RefSeq Peptide - NP_056534
swissprot - P25940
Ensembl - ENSG00000080573
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 col5a3aENSDARG00000098294Danio rerio
 col5a3bENSDARG00000101816Danio rerio
 Col5a3ENSMUSG00000004098Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
COL5A1 / P20908 / collagen type V alpha 1 chainENSG0000013063559
P12107 / COL11A1 / collagen type XI alpha 1 chainENSG0000006071859
P13942 / COL11A2 / collagen type XI alpha 2 chainENSG0000020424854
COL2A1 / P02458 / collagen type II alpha 1 chainENSG0000013921937
COL1A1 / P02452 / collagen type I alpha 1 chainENSG0000010882136
COL3A1 / P02461 / collagen type III alpha 1 chainENSG0000016854235
COL5A2 / P05997 / collagen type V alpha 2 chainENSG0000020426235
COL1A2 / P08123 / collagen type I alpha 2 chainENSG0000016469234
Q8IZC6 / COL27A1 / collagen type XXVII alpha 1 chainENSG0000019673934
Q17RW2 / COL24A1 / collagen type XXIV alpha 1 chainENSG0000017150232


Protein motifs (from Interpro)
Interpro ID Name
 IPR000885  Fibrillar collagen, C-terminal
 IPR001791  Laminin G domain
 IPR008160  Collagen triple helix repeat
 IPR013320  Concanavalin A-like lectin/glucanase domain superfamily
 IPR016133  Insect cysteine-rich antifreeze protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007160 cell-matrix adhesion IEA
 biological_processGO:0030198 extracellular matrix organization TAS
 biological_processGO:0030199 collagen fibril organization NAS
 biological_processGO:0030574 collagen catabolic process TAS
 biological_processGO:0043588 skin development NAS
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005581 collagen trimer IEA
 cellular_componentGO:0005588 collagen type V trimer IEA
 cellular_componentGO:0005788 endoplasmic reticulum lumen TAS
 cellular_componentGO:0031012 extracellular matrix IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005201 extracellular matrix structural constituent NAS
 molecular_functionGO:0005518 collagen binding NAS
 molecular_functionGO:0008201 heparin binding IEA
 molecular_functionGO:0043394 proteoglycan binding IEA


Pathways (from Reactome)
Pathway description
Collagen degradation
Extracellular matrix organization
Collagen biosynthesis and modifying enzymes
Signaling by PDGF
Assembly of collagen fibrils and other multimeric structures
Integrin cell surface interactions
Syndecan interactions
Non-integrin membrane-ECM interactions
ECM proteoglycans
NCAM1 interactions
MET activates PTK2 signaling
Collagen chain trimerization


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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