ENSG00000115596


Homo sapiens

Features
Gene ID: ENSG00000115596
  
Biological name :WNT6
  
Synonyms : Q9Y6F9 / WNT6 / Wnt family member 6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: q35
Gene start: 218859821
Gene end: 218874233
  
Corresponding Affymetrix probe sets: 221608_at (Human Genome U133 Plus 2.0 Array)   221609_s_at (Human Genome U133 Plus 2.0 Array)   222086_s_at (Human Genome U133 Plus 2.0 Array)   71933_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000233948
NCBI entrez gene - 7475     See in Manteia.
OMIM - 604663
RefSeq - NM_006522
RefSeq Peptide - NP_006513
swissprot - Q9Y6F9
Ensembl - ENSG00000115596
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 wnt6bENSDARG00000073935Danio rerio
 WNT6ENSGALG00000011358Gallus gallus
 Wnt6ENSMUSG00000033227Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
WNT1 / P04628 / Wnt family member 1ENSG0000012508444
WNT4 / P56705 / Wnt family member 4ENSG0000016255241
WNT3A / P56704 / Wnt family member 3AENSG0000015434240
WNT5B / Q9H1J7 / Wnt family member 5BENSG0000011118639
WNT3 / P56703 / Wnt family member 3ENSG0000010837939
WNT2B / Q93097 / Wnt family member 2BENSG0000013424539
WNT7B / P56706 / Wnt family member 7BENSG0000018806439
WNT5A / P41221 / Wnt family member 5AENSG0000011425137
WNT7A / O00755 / Wnt family member 7AENSG0000015476437
WNT2 / P09544 / Wnt family member 2ENSG0000010598936
WNT11 / O96014 / Wnt family member 11ENSG0000008574134
WNT16 / Q9UBV4 / Wnt family member 16ENSG0000000274534


Protein motifs (from Interpro)
Interpro ID Name
 IPR005817  Wnt
 IPR009143  Wnt-6 protein
 IPR018161  Wnt protein, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001658 branching involved in ureteric bud morphogenesis IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0009798 axis specification IEA
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0016055 Wnt signaling pathway IBA
 biological_processGO:0030182 neuron differentiation ISS
 biological_processGO:0042475 odontogenesis of dentin-containing tooth IMP
 biological_processGO:0045165 cell fate commitment IBA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0060684 epithelial-mesenchymal cell signaling IEA
 biological_processGO:0061303 cornea development in camera-type eye ISS
 biological_processGO:0070172 positive regulation of tooth mineralization IMP
 biological_processGO:0071300 cellular response to retinoic acid ISS
 biological_processGO:0072079 nephron tubule formation IEA
 biological_processGO:0072080 nephron tubule development IEA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IBA
 cellular_componentGO:0005788 endoplasmic reticulum lumen TAS
 cellular_componentGO:0005796 Golgi lumen TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0030666 endocytic vesicle membrane TAS
 cellular_componentGO:0070062 extracellular exosome TAS
 molecular_functionGO:0005102 signaling receptor binding IEA
 molecular_functionGO:0005109 frizzled binding IBA


Pathways (from Reactome)
Pathway description
WNT ligand biogenesis and trafficking
Class B/2 (Secretin family receptors)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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