ENSG00000002745


Homo sapiens

Features
Gene ID: ENSG00000002745
  
Biological name :WNT16
  
Synonyms : Q9UBV4 / WNT16 / Wnt family member 16
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: 1
Band: q31.31
Gene start: 121325367
Gene end: 121341104
  
Corresponding Affymetrix probe sets: 221113_s_at (Human Genome U133 Plus 2.0 Array)   224022_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000355065
Ensembl peptide - ENSP00000222462
NCBI entrez gene - 51384     See in Manteia.
OMIM - 606267
RefSeq - NM_016087
RefSeq - NM_057168
RefSeq Peptide - NP_057171
RefSeq Peptide - NP_476509
swissprot - Q9UBV4
swissprot - E9PH60
Ensembl - ENSG00000002745
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 wnt16ENSDARG00000094973Danio rerio
 WNT16ENSGALG00000028069Gallus gallus
 Wnt16ENSMUSG00000029671Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
WNT7B / P56706 / Wnt family member 7BENSG0000018806441
WNT2B / Q93097 / Wnt family member 2BENSG0000013424540
WNT5B / Q9H1J7 / Wnt family member 5BENSG0000011118639
WNT4 / P56705 / Wnt family member 4ENSG0000016255239
WNT2 / P09544 / Wnt family member 2ENSG0000010598939
WNT7A / O00755 / Wnt family member 7AENSG0000015476439
WNT3 / P56703 / Wnt family member 3ENSG0000010837939
WNT3A / P56704 / Wnt family member 3AENSG0000015434238
WNT5A / P41221 / Wnt family member 5AENSG0000011425137
WNT1 / P04628 / Wnt family member 1ENSG0000012508436
WNT6 / Q9Y6F9 / Wnt family member 6ENSG0000011559634
WNT11 / O96014 / Wnt family member 11ENSG0000008574134


Protein motifs (from Interpro)
Interpro ID Name
 IPR005817  Wnt
 IPR013304  Wnt-16 protein
 IPR018161  Wnt protein, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003408 optic cup formation involved in camera-type eye development ISS
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0010628 positive regulation of gene expression IMP
 biological_processGO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling IMP
 biological_processGO:0016055 Wnt signaling pathway IBA
 biological_processGO:0030182 neuron differentiation IBA
 biological_processGO:0030216 keratinocyte differentiation IMP
 biological_processGO:0043616 keratinocyte proliferation IMP
 biological_processGO:0045165 cell fate commitment IBA
 biological_processGO:0046330 positive regulation of JNK cascade IMP
 biological_processGO:0046849 bone remodeling IEA
 biological_processGO:0060317 cardiac epithelial to mesenchymal transition IEA
 biological_processGO:0060548 negative regulation of cell death IMP
 biological_processGO:0090399 replicative senescence IMP
 biological_processGO:0090403 oxidative stress-induced premature senescence IMP
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0005737 cytoplasm IDA
 molecular_functionGO:0005102 signaling receptor binding IEA
 molecular_functionGO:0005109 frizzled binding IBA


Pathways (from Reactome)
Pathway description
WNT ligand biogenesis and trafficking
Class B/2 (Secretin family receptors)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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