ENSG00000188064


Homo sapiens

Features
Gene ID: ENSG00000188064
  
Biological name :WNT7B
  
Synonyms : P56706 / WNT7B / Wnt family member 7B
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 22
Strand: -1
Band: q13.31
Gene start: 45920362
Gene end: 45977129
  
Corresponding Affymetrix probe sets: 217681_at (Human Genome U133 Plus 2.0 Array)   238105_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000341032
Ensembl peptide - ENSP00000392750
Ensembl peptide - ENSP00000387217
Ensembl peptide - ENSP00000386781
Ensembl peptide - ENSP00000386546
NCBI entrez gene - 7477     See in Manteia.
OMIM - 601967
RefSeq - XM_011530366
RefSeq - NM_058238
RefSeq Peptide - NP_478679
swissprot - B8A595
swissprot - A8K0G1
swissprot - B8A598
swissprot - P56706
swissprot - B8A597
Ensembl - ENSG00000188064
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 wnt7baENSDARG00000022858Danio rerio
 wnt7bbENSDARG00000071107Danio rerio
 WNT7BENSGALG00000036255Gallus gallus
 Wnt7bENSMUSG00000022382Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
WNT7A / O00755 / Wnt family member 7AENSG0000015476478
WNT2B / Q93097 / Wnt family member 2BENSG0000013424548
WNT4 / P56705 / Wnt family member 4ENSG0000016255246
WNT5A / P41221 / Wnt family member 5AENSG0000011425146
WNT5B / Q9H1J7 / Wnt family member 5BENSG0000011118645
WNT2 / P09544 / Wnt family member 2ENSG0000010598944
WNT3 / P56703 / Wnt family member 3ENSG0000010837944
WNT16 / Q9UBV4 / Wnt family member 16ENSG0000000274543
WNT3A / P56704 / Wnt family member 3AENSG0000015434242
WNT6 / Q9Y6F9 / Wnt family member 6ENSG0000011559640
WNT1 / P04628 / Wnt family member 1ENSG0000012508438
WNT11 / O96014 / Wnt family member 11ENSG0000008574135


Protein motifs (from Interpro)
Interpro ID Name
 IPR005817  Wnt
 IPR013300  Wnt-7 protein
 IPR018161  Wnt protein, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001701 in utero embryonic development ISS
 biological_processGO:0003338 metanephros morphogenesis ISS
 biological_processGO:0007257 activation of JUN kinase activity IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0016332 establishment or maintenance of polarity of embryonic epithelium ISS
 biological_processGO:0021871 forebrain regionalization IEP
 biological_processGO:0022009 central nervous system vasculogenesis ISS
 biological_processGO:0030182 neuron differentiation IEP
 biological_processGO:0030324 lung development ISS
 biological_processGO:0031175 neuron projection development IEA
 biological_processGO:0032364 oxygen homeostasis ISS
 biological_processGO:0032536 regulation of cell projection size IEA
 biological_processGO:0042592 homeostatic process ISS
 biological_processGO:0044237 cellular metabolic process ISS
 biological_processGO:0045165 cell fate commitment IBA
 biological_processGO:0045669 positive regulation of osteoblast differentiation ISS
 biological_processGO:0046330 positive regulation of JNK cascade IEA
 biological_processGO:0048144 fibroblast proliferation IEP
 biological_processGO:0048568 embryonic organ development ISS
 biological_processGO:0048812 neuron projection morphogenesis IEA
 biological_processGO:0050808 synapse organization ISS
 biological_processGO:0051384 response to glucocorticoid IEA
 biological_processGO:0060070 canonical Wnt signaling pathway ISS
 biological_processGO:0060425 lung morphogenesis ISS
 biological_processGO:0060428 lung epithelium development ISS
 biological_processGO:0060482 lobar bronchus development ISS
 biological_processGO:0060535 trachea cartilage morphogenesis ISS
 biological_processGO:0060560 developmental growth involved in morphogenesis ISS
 biological_processGO:0060669 embryonic placenta morphogenesis ISS
 biological_processGO:0060710 chorio-allantoic fusion ISS
 biological_processGO:0061180 mammary gland epithelium development IEP
 biological_processGO:0070307 lens fiber cell development ISS
 biological_processGO:0071300 cellular response to retinoic acid IEP
 biological_processGO:0072053 renal inner medulla development ISS
 biological_processGO:0072054 renal outer medulla development ISS
 biological_processGO:0072060 outer medullary collecting duct development ISS
 biological_processGO:0072061 inner medullary collecting duct development ISS
 biological_processGO:0072089 stem cell proliferation IEP
 biological_processGO:0072205 metanephric collecting duct development ISS
 biological_processGO:0072207 metanephric epithelium development ISS
 biological_processGO:0072236 metanephric loop of Henle development ISS
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005788 endoplasmic reticulum lumen TAS
 cellular_componentGO:0005796 Golgi lumen TAS
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0030666 endocytic vesicle membrane TAS
 cellular_componentGO:0070062 extracellular exosome TAS
 molecular_functionGO:0005102 signaling receptor binding IEA
 molecular_functionGO:0005109 frizzled binding IBA
 molecular_functionGO:0048018 receptor ligand activity IDA


Pathways (from Reactome)
Pathway description
WNT ligand biogenesis and trafficking
Class B/2 (Secretin family receptors)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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