ENSG00000134245


Homo sapiens

Features
Gene ID: ENSG00000134245
  
Biological name :WNT2B
  
Synonyms : Q93097 / WNT2B / Wnt family member 2B
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p13.2
Gene start: 112466541
Gene end: 112530165
  
Corresponding Affymetrix probe sets: 206458_s_at (Human Genome U133 Plus 2.0 Array)   206459_s_at (Human Genome U133 Plus 2.0 Array)   236123_at (Human Genome U133 Plus 2.0 Array)   238512_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000256640
Ensembl peptide - ENSP00000358698
Ensembl peptide - ENSP00000358700
NCBI entrez gene - 7482     See in Manteia.
OMIM - 601968
RefSeq - NM_004185
RefSeq - NM_001291880
RefSeq - NM_024494
RefSeq Peptide - NP_001278809
RefSeq Peptide - NP_004176
RefSeq Peptide - NP_078613
swissprot - Q5TEH8
swissprot - Q93097
Ensembl - ENSG00000134245
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 wnt2baENSDARG00000005050Danio rerio
 wnt2bbENSDARG00000032234Danio rerio
 WNT2BENSGALG00000034196Gallus gallus
 Wnt2bENSMUSG00000027840Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
WNT2 / P09544 / Wnt family member 2ENSG0000010598963
WNT5A / P41221 / Wnt family member 5AENSG0000011425145
WNT5B / Q9H1J7 / Wnt family member 5BENSG0000011118644
WNT7B / P56706 / Wnt family member 7BENSG0000018806442
WNT4 / P56705 / Wnt family member 4ENSG0000016255242
WNT7A / O00755 / Wnt family member 7AENSG0000015476442
WNT3 / P56703 / Wnt family member 3ENSG0000010837939
WNT16 / Q9UBV4 / Wnt family member 16ENSG0000000274538
WNT1 / P04628 / Wnt family member 1ENSG0000012508438
WNT3A / P56704 / Wnt family member 3AENSG0000015434238
WNT6 / Q9Y6F9 / Wnt family member 6ENSG0000011559636
WNT11 / O96014 / Wnt family member 11ENSG0000008574134


Protein motifs (from Interpro)
Interpro ID Name
 IPR005817  Wnt
 IPR009140  Wnt-2 protein
 IPR018161  Wnt protein, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002062 chondrocyte differentiation IEP
 biological_processGO:0002088 lens development in camera-type eye ISS
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0008584 male gonad development IEP
 biological_processGO:0009267 cellular response to starvation IEA
 biological_processGO:0016055 Wnt signaling pathway TAS
 biological_processGO:0021871 forebrain regionalization IEA
 biological_processGO:0030182 neuron differentiation ISS
 biological_processGO:0045165 cell fate commitment IBA
 biological_processGO:0060070 canonical Wnt signaling pathway IEA
 biological_processGO:0060492 lung induction IEA
 biological_processGO:0060638 mesenchymal-epithelial cell signaling IEA
 biological_processGO:0061072 iris morphogenesis ISS
 biological_processGO:0061303 cornea development in camera-type eye ISS
 biological_processGO:0071425 hematopoietic stem cell proliferation IDA
 biological_processGO:0090190 positive regulation of branching involved in ureteric bud morphogenesis IEA
 biological_processGO:0090263 positive regulation of canonical Wnt signaling pathway IDA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IBA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 molecular_functionGO:0005102 signaling receptor binding IEA
 molecular_functionGO:0005109 frizzled binding IBA


Pathways (from Reactome)
Pathway description
WNT ligand biogenesis and trafficking
Class B/2 (Secretin family receptors)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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