ENSMUSG00000027840


Mus musculus

Features
Gene ID: ENSMUSG00000027840
  
Biological name :Wnt2b
  
Synonyms : O70283 / wingless-type MMTV integration site family, member 2B / Wnt2b
  
Possible biological names infered from orthology : Q93097 / Wnt family member 2B
  
Species: Mus musculus
  
Chr. number: 3
Strand: -1
Band: F2.2
Gene start: 104945272
Gene end: 104961921
  
Corresponding Affymetrix probe sets: 10500938 (MoGene1.0st)   1421465_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000029429
NCBI entrez gene - 22414     See in Manteia.
MGI - MGI:1261834
RefSeq - NM_009520
RefSeq Peptide - NP_033546
swissprot - O70283
Ensembl - ENSMUSG00000027840
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 wnt2baENSDARG00000005050Danio rerio
 wnt2bbENSDARG00000032234Danio rerio
 WNT2BENSGALG00000034196Gallus gallus
 WNT2BENSG00000134245Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Wnt2 / P21552 / wingless-type MMTV integration site family, member 2 / P09544* / Wnt family member 2*ENSMUSG0000001079763
Wnt5a / P22725 / wingless-type MMTV integration site family, member 5A / P41221* / Wnt family member 5A*ENSMUSG0000002199445
Wnt5b / P22726 / wingless-type MMTV integration site family, member 5B / Q9H1J7* / Wnt family member 5B*ENSMUSG0000003017045
Wnt7b / P28047 / wingless-type MMTV integration site family, member 7B / P56706* / Wnt family member 7B*ENSMUSG0000002238244
Wnt7a / P24383 / wingless-type MMTV integration site family, member 7A / O00755* / Wnt family member 7A*ENSMUSG0000003009342
Wnt4 / P22724 / wingless-type MMTV integration site family, member 4 / P56705* / Wnt family member 4*ENSMUSG0000003685641
Wnt3 / P17553 / wingless-type MMTV integration site family, member 3 / P56703* / Wnt family member 3*ENSMUSG0000000012539
Wnt16 / Q9QYS1 / wingless-type MMTV integration site family, member 16 / Q9UBV4* / Wnt family member 16*ENSMUSG0000002967138
Wnt1 / P04426 / wingless-type MMTV integration site family, member 1 / P04628* / Wnt family member 1*ENSMUSG0000002299738
Wnt3a / P27467 / wingless-type MMTV integration site family, member 3A / P56704* / Wnt family member 3A*ENSMUSG0000000990037
Wnt6 / P22727 / wingless-type MMTV integration site family, member 6 / Q9Y6F9* / Wnt family member 6*ENSMUSG0000003322736
Wnt11 / P48615 / wingless-type MMTV integration site family, member 11 / O96014* / Wnt family member 11*ENSMUSG0000001595733


Protein motifs (from Interpro)
Interpro ID Name
 IPR005817  Wnt
 IPR009140  Wnt-2 protein
 IPR018161  Wnt protein, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002062 chondrocyte differentiation IEA
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007267 cell-cell signaling TAS
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0008584 male gonad development IEA
 biological_processGO:0009267 cellular response to starvation IEP
 biological_processGO:0009887 animal organ morphogenesis TAS
 biological_processGO:0016055 Wnt signaling pathway ISO
 biological_processGO:0021871 forebrain regionalization IEP
 biological_processGO:0030182 neuron differentiation IBA
 biological_processGO:0045165 cell fate commitment IBA
 biological_processGO:0060070 canonical Wnt signaling pathway IGI
 biological_processGO:0060492 lung induction IGI
 biological_processGO:0060638 mesenchymal-epithelial cell signaling IDA
 biological_processGO:0071425 hematopoietic stem cell proliferation IEA
 biological_processGO:0090190 positive regulation of branching involved in ureteric bud morphogenesis IDA
 biological_processGO:0090263 positive regulation of canonical Wnt signaling pathway IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IBA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0005102 signaling receptor binding TAS
 molecular_functionGO:0005109 frizzled binding IBA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
WNT ligand biogenesis and trafficking


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001181 absent lungs "missing organs of respiration" [J:51966, J:50768]
Show

Allelic Composition: Hunktm1Lach/Hunk+,Tg(MMTV-Myc)#Led/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * CD-1

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Hunktm1Lach/Hunk+,Tg(MMTV-Myc)#Led/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * CD-1

 MP:0010885 absent trachea "absence of the tube descending from the larynx and branching into the right and left main bronchi" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Hunktm1Lach/Hunk+,Tg(MMTV-Myc)#Led/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * CD-1

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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