ENSMUSG00000029671


Mus musculus

Features
Gene ID: ENSMUSG00000029671
  
Biological name :Wnt16
  
Synonyms : Q9QYS1 / wingless-type MMTV integration site family, member 16 / Wnt16
  
Possible biological names infered from orthology : Q9UBV4 / Wnt family member 16
  
Species: Mus musculus
  
Chr. number: 6
Strand: 1
Band: A3.1
Gene start: 22288227
Gene end: 22298522
  
Corresponding Affymetrix probe sets: 10536658 (MoGene1.0st)   1422941_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000031681
Ensembl peptide - ENSMUSP00000134822
Ensembl peptide - ENSMUSP00000135016
Ensembl peptide - ENSMUSP00000135598
NCBI entrez gene - 93735     See in Manteia.
MGI - MGI:2136018
RefSeq - XM_006505214
RefSeq - NM_053116
RefSeq Peptide - NP_444346
swissprot - H3BJ29
swissprot - Q8BRT3
swissprot - Q9QYS1
swissprot - H3BL02
Ensembl - ENSMUSG00000029671
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 wnt16ENSDARG00000094973Danio rerio
 WNT16ENSGALG00000028069Gallus gallus
 WNT16ENSG00000002745Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Wnt7b / P28047 / wingless-type MMTV integration site family, member 7B / P56706* / Wnt family member 7B*ENSMUSG0000002238241
Wnt3 / P17553 / wingless-type MMTV integration site family, member 3 / P56703* / Wnt family member 3*ENSMUSG0000000012540
Wnt3a / P27467 / wingless-type MMTV integration site family, member 3A / P56704* / Wnt family member 3A*ENSMUSG0000000990040
Wnt2 / P21552 / wingless-type MMTV integration site family, member 2 / P09544* / Wnt family member 2*ENSMUSG0000001079740
Wnt2b / O70283 / wingless-type MMTV integration site family, member 2B / Q93097* / Wnt family member 2B*ENSMUSG0000002784040
Wnt7a / P24383 / wingless-type MMTV integration site family, member 7A / O00755* / Wnt family member 7A*ENSMUSG0000003009339
Wnt4 / P22724 / wingless-type MMTV integration site family, member 4 / P56705* / Wnt family member 4*ENSMUSG0000003685639
Wnt5b / P22726 / wingless-type MMTV integration site family, member 5B / Q9H1J7* / Wnt family member 5B*ENSMUSG0000003017039
Wnt5a / P22725 / wingless-type MMTV integration site family, member 5A / P41221* / Wnt family member 5A*ENSMUSG0000002199438
Wnt1 / P04426 / wingless-type MMTV integration site family, member 1 / P04628* / Wnt family member 1*ENSMUSG0000002299737
Wnt11 / P48615 / wingless-type MMTV integration site family, member 11 / O96014* / Wnt family member 11*ENSMUSG0000001595736
Wnt6 / P22727 / wingless-type MMTV integration site family, member 6 / Q9Y6F9* / Wnt family member 6*ENSMUSG0000003322735


Protein motifs (from Interpro)
Interpro ID Name
 IPR005817  Wnt
 IPR013304  Wnt-16 protein
 IPR018161  Wnt protein, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling IEA
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0030182 neuron differentiation IBA
 biological_processGO:0030216 keratinocyte differentiation IEA
 biological_processGO:0043616 keratinocyte proliferation IEA
 biological_processGO:0045165 cell fate commitment IBA
 biological_processGO:0046330 positive regulation of JNK cascade IEA
 biological_processGO:0046849 bone remodeling IMP
 biological_processGO:0060317 cardiac epithelial to mesenchymal transition IMP
 biological_processGO:0060548 negative regulation of cell death IEA
 biological_processGO:0090399 replicative senescence IEA
 biological_processGO:0090403 oxidative stress-induced premature senescence IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0005102 signaling receptor binding IEA
 molecular_functionGO:0005109 frizzled binding IBA


Pathways (from Reactome)
Pathway description
WNT ligand biogenesis and trafficking


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000135 reduced cortical bone thickness "thinner than normal superficial layer of compact bone " [J:61509]
Show

Allelic Composition: Atxn2tm2.1Geno/Atxn2tm2.1Geno
Genetic Background: B6.129S2-Atxn2tm2.1Geno

 MP:0004991 decreased bone strength "reduced ability of bone to endure the application of force without yielding or breaking" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Atxn2tm2.1Geno/Atxn2tm2.1Geno
Genetic Background: B6.129S2-Atxn2tm2.1Geno

 MP:0010968 decreased compact bone area "reduction in the total amount of cross-sectional area of compact bone tissue" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Atxn2tm2.1Geno/Atxn2tm2.1Geno
Genetic Background: B6.129S2-Atxn2tm2.1Geno

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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