ENSG00000111186


Homo sapiens

Features
Gene ID: ENSG00000111186
  
Biological name :WNT5B
  
Synonyms : Q9H1J7 / WNT5B / Wnt family member 5B
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: 1
Band: p13.33
Gene start: 1529891
Gene end: 1647243
  
Corresponding Affymetrix probe sets: 221029_s_at (Human Genome U133 Plus 2.0 Array)   223537_s_at (Human Genome U133 Plus 2.0 Array)   230299_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000438414
Ensembl peptide - ENSP00000439312
Ensembl peptide - ENSP00000440600
Ensembl peptide - ENSP00000442348
Ensembl peptide - ENSP00000445395
Ensembl peptide - ENSP00000308887
Ensembl peptide - ENSP00000380379
NCBI entrez gene - 81029     See in Manteia.
OMIM - 606361
RefSeq - NM_032642
RefSeq - NM_030775
RefSeq Peptide - NP_110402
RefSeq Peptide - NP_116031
swissprot - Q9H1J7
swissprot - F5GYM2
swissprot - F5H034
swissprot - F5H364
swissprot - F5H7Q6
Ensembl - ENSG00000111186
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 wnt5bENSDARG00000102464Danio rerio
 WNT5BENSGALG00000012998Gallus gallus
 Wnt5bENSMUSG00000030170Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
WNT5A / P41221 / Wnt family member 5AENSG0000011425181
WNT2B / Q93097 / Wnt family member 2BENSG0000013424548
WNT2 / P09544 / Wnt family member 2ENSG0000010598946
WNT3 / P56703 / Wnt family member 3ENSG0000010837945
WNT4 / P56705 / Wnt family member 4ENSG0000016255245
WNT3A / P56704 / Wnt family member 3AENSG0000015434245
WNT7B / P56706 / Wnt family member 7BENSG0000018806444
WNT7A / O00755 / Wnt family member 7AENSG0000015476443
WNT6 / Q9Y6F9 / Wnt family member 6ENSG0000011559640
WNT16 / Q9UBV4 / Wnt family member 16ENSG0000000274540
WNT11 / O96014 / Wnt family member 11ENSG0000008574138
WNT1 / P04628 / Wnt family member 1ENSG0000012508437


Protein motifs (from Interpro)
Interpro ID Name
 IPR005817  Wnt
 IPR018161  Wnt protein, conserved site
 IPR026537  Wnt-5b protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002062 chondrocyte differentiation IEP
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0030182 neuron differentiation ISS
 biological_processGO:0030335 positive regulation of cell migration IDA
 biological_processGO:0042060 wound healing IEA
 biological_processGO:0045165 cell fate commitment IBA
 biological_processGO:0045444 fat cell differentiation NAS
 biological_processGO:0045600 positive regulation of fat cell differentiation IEA
 biological_processGO:0070307 lens fiber cell development ISS
 biological_processGO:0071300 cellular response to retinoic acid ISS
 biological_processGO:0090090 negative regulation of canonical Wnt signaling pathway IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IBA
 cellular_componentGO:0005788 endoplasmic reticulum lumen TAS
 cellular_componentGO:0005796 Golgi lumen TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0030666 endocytic vesicle membrane TAS
 cellular_componentGO:0070062 extracellular exosome TAS
 molecular_functionGO:0005102 signaling receptor binding IEA
 molecular_functionGO:0005109 frizzled binding IBA


Pathways (from Reactome)
Pathway description
WNT ligand biogenesis and trafficking
PCP/CE pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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