ENSG00000128645


Homo sapiens

Features
Gene ID: ENSG00000128645
  
Biological name :HOXD1
  
Synonyms : homeobox D1 / HOXD1 / Q9GZZ0
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: q31.1
Gene start: 176188579
Gene end: 176190907
  
Corresponding Affymetrix probe sets: 205974_at (Human Genome U133 Plus 2.0 Array)   205975_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000328598
NCBI entrez gene - 3231     See in Manteia.
OMIM - 142987
RefSeq - NM_024501
RefSeq - XM_005246507
RefSeq Peptide - NP_078777
swissprot - Q9GZZ0
Ensembl - ENSG00000128645
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hoxc1aENSDARG00000070337Danio rerio
 Hoxd1ENSMUSG00000042448Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HOXA1 / P49639 / homeobox A1ENSG0000010599136
HOXB1 / P14653 / homeobox B1ENSG0000012009436
HOXD3 / P31249 / homeobox D3ENSG0000012865223
HOXB3 / P14651 / homeobox B3ENSG0000012009323
HOXB2 / P14652 / homeobox B2ENSG0000017391722
HOXA3 / O43365 / homeobox A3ENSG0000010599721
GSX1 / Q9H4S2 / GS homeobox 1ENSG0000016984020
PDX1 / P52945 / pancreatic and duodenal homeobox 1ENSG0000013951520
HOXA2 / O43364 / homeobox A2ENSG0000010599620
GSX2 / Q9BZM3 / GS homeobox 2ENSG0000018061318


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site
 IPR020479  Homeobox domain, metazoa


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0019233 sensory perception of pain IEA
 biological_processGO:0030182 neuron differentiation IEA
 biological_processGO:0048706 embryonic skeletal system development IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
Activation of anterior HOX genes in hindbrain development during early embryogenesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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