ENSMUSG00000042448


Mus musculus

Features
Gene ID: ENSMUSG00000042448
  
Biological name :Hoxd1
  
Synonyms : Homeobox protein Hox-D1 / Hoxd1 / Q01822
  
Possible biological names infered from orthology : homeobox D1 / Q9GZZ0
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: C3
Gene start: 74762980
Gene end: 74765142
  
Corresponding Affymetrix probe sets: 10472989 (MoGene1.0st)   1420573_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000043078
NCBI entrez gene - 15429     See in Manteia.
MGI - MGI:96201
RefSeq - NM_010467
RefSeq Peptide - NP_034597
swissprot - Q01822
Ensembl - ENSMUSG00000042448
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hoxc1aENSDARG00000070337Danio rerio
 HOXD1ENSG00000128645Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Hoxa1 / homeobox A1 / P49639*ENSMUSG0000002984434
Hoxb1 / P17919 / Homeobox protein Hox-B1 / P14653* / homeobox B1*ENSMUSG0000001897333
Hoxb3 / P09026 / Homeobox protein Hox-B3 / P14651* / homeobox B3*ENSMUSG0000004876323
Hoxd3 / P09027 / homeobox D3 / P31249*ENSMUSG0000007927722
Hoxb2 / P0C1T1 / Homeobox protein Hox-B2 / P14652* / homeobox B2*ENSMUSG0000007558822
Hoxa3 / P02831 / Homeobox protein Hox-A3 / O43365* / homeobox A3*ENSMUSG0000007956021
Hoxa2 / P31245 / Homeobox protein Hox-A2 / O43364* / homeobox A2*ENSMUSG0000001470420
Gsx1 / P31315 / GS homeobox 1 / Q9H4S2*ENSMUSG0000005312920
Pdx1 / P52946 / Pancreas/duodenum homeobox protein 1 / P52945* / pancreatic and duodenal homeobox 1*ENSMUSG0000002964418
Gsx2 / P31316 / GS homeobox 2 / Q9BZM3*ENSMUSG0000003594618
Gm28308ENSMUSG000001012981


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site
 IPR020479  Homeobox domain, metazoa


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0019233 sensory perception of pain IMP
 biological_processGO:0030182 neuron differentiation IMP
 biological_processGO:0048706 embryonic skeletal system development IMP
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000968 abnormal sensory neuron innervation "defective or incomplete supply of nerve fibers to sensory termini or to spinal cord" [J:31622]
Show

Allelic Composition: Lama2tm1Eeng/Lama2tm1Eeng
Genetic Background: involves: 129S1/Sv

 MP:0001973 increased thermal nociceptive threshold "a greater than average point at which thermal pain sensation is first detectable" [What s Wrong With My Mouse?:ISBN 0-471-31639-3, J:17194]
Show

Allelic Composition: Lama2tm1Eeng/Lama2tm1Eeng
Genetic Background: involves: 129S1/Sv

 MP:0002736 abnormal nociception after inflammation "changes in pain thresholds after inflammation" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Lama2tm1Eeng/Lama2tm1Eeng
Genetic Background: involves: 129S1/Sv

 MP:0003048 abnormal cervical vertebrae morphology "malformation of any or all of the seven bony segments of the spine located anterior to the thoracic vertebrae" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]
Show

Allelic Composition: Catf/Catf
Genetic Background: Not Specified

 MP:0004607 abnormal cervical atlas morphology "any structural anomaly of the first (topmost, C1) cervical vertebra which supports the globe of the head" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Catf/Catf
Genetic Background: Not Specified

 MP:0004620 cervical vertebral fusion "the union of one or more cervical vertebrae into a single structure" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Catf/Catf
Genetic Background: Not Specified

 MP:0010728 fusion of atlas and occipital bones "union of elements of the atlas and the bone at the lower, posterior part of the skull into one structure" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Catf/Catf
Genetic Background: Not Specified

 MP:0010729 absent arcus anterior "absence of the arch that connects the lateral masses of the atlas anteriorly and articulates with the anterior articular facet of the dens of the axis" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Catf/Catf
Genetic Background: Not Specified

 MP:0010730 absent odontoid process "absence of the large protuberance that projects upward from the cervical axis, around which the cervical atlas rotates" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Catf/Catf
Genetic Background: Not Specified

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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