MP:0000078 | abnormal supraoccipital bone morphology | "malformed upper part of the occipital bone" [J:61509] |
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Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm1Mrc,Hoxb3tm1Mrc/Hoxb3tm1Mrc Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6J
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MP:0000079 | abnormal basioccipital bone morphology | "malformed basilar process of the occipital bone" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:55583] |
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Allelic Composition: Hoxa3tm2Nrm/Hoxa3tm3.1Nrm,H2afvTg(Wnt1-cre)11Rth/0 Genetic Background: involves: C3H * C57BL/6 * CBA/J
Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm1Mrc,Hoxd3tm1Mrc/Hoxd3tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
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MP:0000088 | short mandible | "reduced length of the lower bony framework of the mouth where the inferior teeth are held" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
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MP:0000097 | short maxilla | "reduced length of the upper jaw bone" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:53370] |
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Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
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MP:0000678 | abnormal parathyroid gland morphology | "anomalous structure of one of the two small, paired endocrine glands, usually found embedded in the connective tissue capsule on the posterior surface of the thyroid gland; they secrete parathyroid hormone (PTH) that regulates calcium and phosphorous metabolism" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Fgf8tm1Mrc/Fgf8tm1Moon,Tfap2atm1(cre)Moon/Tfap2a+ Genetic Background: involves: 129/Sv * C57BL/6
Allelic Composition: Fgf8tm1Mrc/Fgf8tm1Moon,Hoxa3tm1(cre)Moon/Hoxa3+ Genetic Background: involves: 129/Sv * C57BL/6
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MP:0000680 | absent parathyroid glands | "missing the two small, paired endocrine glands, usually found embedded in the connective tissue capsule on the posterior surface of the thyroid gland, which secrete parathyroid hormone (PTH) " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Fgf8tm1Mrc/Fgf8tm1Moon,Tfap2atm1(cre)Moon/Tfap2a+ Genetic Background: involves: 129/Sv * C57BL/6
Allelic Composition: Fgf8tm1Mrc/Fgf8tm1Moon,Hoxa3tm1(cre)Moon/Hoxa3+ Genetic Background: involves: 129/Sv * C57BL/6
Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm2Nrm Genetic Background: involves: 129S7/SvEvBrd * C3H * C57BL/6 * C57BL/6NHsd
Allelic Composition: Hoxa3tm2Nrm/Hoxa3tm2Nrm Genetic Background: involves: C3H * C57BL/6 * C57BL/6NHsd
Allelic Composition: Hoxa3tm1Nrm/Hoxa3tm1Mrc Genetic Background: involves: 129S7/SvEvBrd * C3H * C57BL/6 * C57BL/6NHsd
Allelic Composition: Hoxa3tm1Nrm/Hoxa3tm1Nrm Genetic Background: involves: C3H * C57BL/6 * C57BL/6NHsd
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MP:0000681 | abnormal thyroid gland morphology | "anomalous structure of the endocrine gland located in the front and to the sides of the upper part of the trachea and which secretes thyroid hormone and calcitonin" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Plp1jp-rsh/Y Genetic Background: C57BL/6NCrl
Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm1Mrc,Hoxd3tm1Mrc/Hoxd3tm1Mrc Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
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MP:0000705 | athymia | "absence of the primary lymphoid organ" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm1Mrc,Hoxd3tm1Mrc/Hoxd3tm1Mrc Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
Allelic Composition: Hoxa3tm1Kth/Hoxa3tm1Kth Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Hoxa3tm1Kth/Hoxa3tm1Kth,Hoxd3tm3(Hoxa3)Mrc/Hoxd3+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm2Nrm Genetic Background: involves: 129S7/SvEvBrd * C3H * C57BL/6 * C57BL/6NHsd
Allelic Composition: Hoxa3tm2Nrm/Hoxa3tm2Nrm Genetic Background: involves: C3H * C57BL/6 * C57BL/6NHsd
Allelic Composition: Hoxa3tm1Nrm/Hoxa3tm1Mrc Genetic Background: involves: 129S7/SvEvBrd * C3H * C57BL/6 * C57BL/6NHsd
Allelic Composition: Hoxa3tm1Nrm/Hoxa3tm1Nrm Genetic Background: involves: C3H * C57BL/6 * C57BL/6NHsd
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MP:0000966 | reduced sensory neuron number | "fewer than normal numbers of cells that innervate an effector (muscle or glandular) tissue" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:60159] |
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Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm1Mrc,Hoxb3tm1Mrc/Hoxb3tm1Mrc Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6J
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MP:0001051 | abnormal somatic motor system morphology | |
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Allelic Composition: Gabrg2tm2Lusc/Gabrg2tm2Lusc,Tg(Camk2a-cre)T50Stl/0 Genetic Background: involves: 129X1/SvJ * BALB/c * C57BL/6
Allelic Composition: Hoxa3tm3Mrc/Hoxa3tm3Mrc,Hoxb3tm1Mrc/Hoxb3tm1Mrc Genetic Background: involves: 129S4/SvJae
Allelic Composition: Hoxa3tm3Mrc/Hoxa3tm3Mrc,Hoxd3tm2Mrc/Hoxd3tm2Mrc Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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MP:0001073 | abnormal glossopharyngeal nerve morphology | "malformed or misprojection of sensory and autonomic axons to the parotid gland, carotid body, posterior third of the tongue" [Principles of Neural Science:ISBN 0-8385-8034-3, J:33038] |
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Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm2Nrm Genetic Background: involves: 129S7/SvEvBrd * C3H * C57BL/6 * C57BL/6NHsd
Allelic Composition: Hoxa3tm2Nrm/Hoxa3tm2Nrm Genetic Background: involves: C3H * C57BL/6 * C57BL/6NHsd
Allelic Composition: Hoxa3tm1Nrm/Hoxa3tm1Mrc Genetic Background: involves: 129S7/SvEvBrd * C3H * C57BL/6 * C57BL/6NHsd
Allelic Composition: Hoxa3tm1Nrm/Hoxa3tm1Nrm Genetic Background: involves: C3H * C57BL/6 * C57BL/6NHsd
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MP:0001270 | distended abdomen | "abdomen appears curved outward or swollen; can be due to skeletal axial defects, enlarged visceral organs or megacolon" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Plp1jp-rsh/Y Genetic Background: C57BL/6NCrl
Allelic Composition: Hoxa3tm1Nrm/Hoxa3tm1Mrc Genetic Background: involves: 129S7/SvEvBrd * C3H * C57BL/6 * C57BL/6NHsd
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MP:0001823 | thymus hypoplasia | "small size due to reduced cell number in the thymus" [J:23255] |
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Allelic Composition: Fgf8tm1Mrc/Fgf8tm1Moon,Tfap2atm1(cre)Moon/Tfap2a+ Genetic Background: involves: 129/Sv * C57BL/6
Allelic Composition: Fgf8tm1Mrc/Fgf8tm1Moon,Hoxa3tm1(cre)Moon/Hoxa3+ Genetic Background: involves: 129/Sv * C57BL/6
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MP:0002058 | neonatal lethality | "death of animal within one day after birth" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Hoxa3tm1Kth/Hoxa3tm1Kth Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm2Nrm Genetic Background: involves: 129S7/SvEvBrd * C3H * C57BL/6 * C57BL/6NHsd
Allelic Composition: Hoxa3tm2Nrm/Hoxa3tm2Nrm Genetic Background: involves: C3H * C57BL/6 * C57BL/6NHsd
Allelic Composition: Hoxa3tm1Nrm/Hoxa3tm1Mrc Genetic Background: involves: 129S7/SvEvBrd * C3H * C57BL/6 * C57BL/6NHsd
Allelic Composition: Hoxa3tm1Nrm/Hoxa3tm1Nrm Genetic Background: involves: C3H * C57BL/6 * C57BL/6NHsd
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MP:0002081 | perinatal lethality | "death anytime between E18.5 and postnatal day 1 " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Ppp1r13lwa3-J/Ppp1r13lwa3-J Genetic Background: BALB/cJ-Ppp1r13lwa3-J/J
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MP:0002108 | abnormal muscle morphology | "abnormal development of muscle tissue resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Plp1jp-rsh/Y Genetic Background: C57BL/6NCrl
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MP:0002114 | abnormal axial skeleton morphology | "abnormal development of vertebral, spinal or sternal bones resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Hoxa3tm2Nrm/Hoxa3tm3.1Nrm,H2afvTg(Wnt1-cre)11Rth/0 Genetic Background: involves: C3H * C57BL/6 * CBA/J
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MP:0002127 | abnormal cardiovascular system morphology | "abnormal development of the heart or vascular tissue resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Plp1jp-rsh/Y Genetic Background: C57BL/6NCrl
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MP:0002132 | abnormal respiratory system morphology | "anomalous structure of pulmonary tissues " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Plp1jp-rsh/Y Genetic Background: C57BL/6NCrl
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MP:0002249 | abnormal larynx morphology | "any structural anomaly of the most superior portion of the respiratory tract" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Pathology , 2nd edition:ISBN 0-397-51047-0] |
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Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
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MP:0002256 | abnormal laryngeal cartilage morphology | "any structural anomaly of the cartilagenous structures that support the larynx" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Pathology , 2nd edition:ISBN 0-397-51047-0] |
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Allelic Composition: Aspatm1Mata/Aspatm1Mata Genetic Background: involves: 129S5/SvEvBrd
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MP:0002258 | abnormal cricoid cartilage morphology | "any structural anomaly of the most inferior of the laryngeal cartilages " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Pathology , 2nd edition:ISBN 0-397-51047-0] |
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Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm1Mrc,Hoxb3tm1Mrc/Hoxb3tm1Mrc Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6J
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MP:0002260 | abnormal thyroid cartilage morphology | "any structural anomaly of the largest of the laryngeal cartilages " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Pathology , 2nd edition:ISBN 0-397-51047-0] |
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Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm1Mrc,Hoxb3tm1Mrc/Hoxb3tm1Mrc Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6J
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MP:0002282 | abnormal trachea morphology | "structral anomaly of the tube descending from the larynx and branching into the right and left main bronchi" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
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MP:0002633 | persistent truncus arteriosis | "complete failure of the common arterial trunk opening out of both ventricles to divide into the aorta and pulmonary artery during development" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
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Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Hoxa3tm1(cre)Moon/Hoxa3+,Tbx1tm3Bld/Tbx1tm1Bld Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
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MP:0002672 | abnormal branchial arch artery morphology | "malformation of the vessels formed within the five pairs of branchial arches in embryogenesis; in the adult, some of these vessels give rise to the great vessels" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Fgf8tm1Mrc/Fgf8tm1Moon,Tfap2atm1(cre)Moon/Tfap2a+ Genetic Background: involves: 129/Sv * C57BL/6
Allelic Composition: Fgf8tm1Mrc/Fgf8tm1Moon,Hoxa3tm1(cre)Moon/Hoxa3+ Genetic Background: involves: 129/Sv * C57BL/6
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MP:0002725 | abnormal vein morphology | "malformation of the blood vessels that carry blood towards the heart" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
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MP:0002753 | dilated left ventricle | "an expansion in the volume of the lower left chamber of the heart" [J:82859, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
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Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
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MP:0002884 | abnormal branchial arches | "malformation or anomaly in the transient structures of the embryo that develop into regions of the head, neck and ears" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
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MP:0002951 | small thyroid gland | "reduced size of the endocrine gland located in the front and to the sides of the upper part of the trachea, and which secretes thyroid hormone and calcitonin " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
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Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
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MP:0003007 | ectopic thymus | "ectopic location of the thymus primordium, which normally resides in the superior mediastinum and lower part of the neck" [ava:Anna V. Anagnostopoulos , Mouse Genome Informatics Curator, J:76015] |
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Allelic Composition: Fgf8tm1Mrc/Fgf8tm2Mrc,Hoxa3tm1(cre)Moon/Hoxa3+ Genetic Background: involves: 129/Sv * C57BL/6
Allelic Composition: Fgf8tm1Mrc/Fgf8tm1Moon,Hoxa3tm1(cre)Moon/Hoxa3+ Genetic Background: involves: 129/Sv * C57BL/6
Allelic Composition: Hoxa3tm1Mrc/Hoxa3+,Hoxb3tm1Mrc/Hoxb3tm1Mrc Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6J
Allelic Composition: Hoxa3tm1Mrc/Hoxa3+,Hoxd3tm1Mrc/Hoxd3tm1Mrc Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm3.1Nrm,H2afvTg(Wnt1-cre)11Rth/0 Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J * CBA/J
Allelic Composition: Hoxa3tm2Nrm/Hoxa3tm3.1Nrm,H2afvTg(Wnt1-cre)11Rth/0 Genetic Background: involves: C3H * C57BL/6 * CBA/J
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MP:0003048 | abnormal cervical vertebrae morphology | "malformation of any or all of the seven bony segments of the spine located anterior to the thoracic vertebrae" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, csmith:Cynthia L. Smith, Mouse Genome Informatics Curator] |
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Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm1Mrc,Hoxb3tm1Mrc/Hoxb3tm1Mrc Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6J
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MP:0003056 | abnormal hyoid bone | "anomalous structure of the U-shaped bone lying between the mandible and the larynx that supports the tongue muscles" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8, hdene:Howard Dene, Mouse Genome Informatics Curator] |
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Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm1Mrc,Hoxb3tm1Mrc/Hoxb3tm1Mrc Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6J
Allelic Composition: Hoxa3tm1Kth/Hoxa3tm1Kth Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Hoxa3tm1Kth/Hoxa3tm1Kth,Hoxd3tm3(Hoxa3)Mrc/Hoxd3+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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MP:0003154 | abnormal soft palate | "abnormality in the musculomembranous fold that partly separates the mouth and pharynx, located behind the hard palate" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Hoxa3tm1Nrm/Hoxa3tm1Mrc Genetic Background: involves: 129S7/SvEvBrd * C3H * C57BL/6 * C57BL/6NHsd
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MP:0003445 | sirenomelia | "fusion of the posterior limbs often with partial or complete fusion of the autopods" [J:67375] |
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Allelic Composition: Pcdh15av/Pcdh15av Genetic Background: involves: K
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MP:0003494 | parathyroid hypoplasia | |
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Allelic Composition: Fgf8tm1Mrc/Fgf8tm2Mrc,Hoxa3tm1(cre)Moon/Hoxa3+ Genetic Background: involves: 129/Sv * C57BL/6
Allelic Composition: Fgf8tm1Mrc/Fgf8tm1Moon,Hoxa3tm1(cre)Moon/Hoxa3+ Genetic Background: involves: 129/Sv * C57BL/6
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MP:0003743 | abnormal facial morphology | "anomalous structure or development of the face" [ncbi:Matthew Mailman, NCBI request] |
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Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
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MP:0003955 | abnormal ultimobranchial body | "a sac-like structure emanating from the caudal-most branchial pouch of the embryo; develops into the lateral portion of the thyroid that produced calcitonin in higher vertebrates" [hdene:Howard Dene , Mouse Genome Informatics Curator] |
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Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm1Mrc,Hoxb3tm1Mrc/Hoxb3tm1Mrc Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6J
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MP:0004136 | abnormal tongue muscle morphology | "anomalous structure or development of the muscular portion of the tongue" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
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MP:0004445 | small exoccipital bone | "reduced size of the bone or region on the lateral sides of the great foremen of the skull, which often forms a part of the occipital in the adult, but is usually distinct in the young" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm1Mrc,Hoxb3tm1Mrc/Hoxb3tm1Mrc Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6J
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MP:0004549 | small trachea | "reduced size of the tube descending from the larynx and branching into the right and left main bronchi" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
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MP:0004568 | fusion of glossopharyngeal and vagus nerve | "union of the ninth and tenth cranial nerves into a single structure" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm2Nrm Genetic Background: involves: 129S7/SvEvBrd * C3H * C57BL/6 * C57BL/6NHsd
Allelic Composition: Hoxa3tm2Nrm/Hoxa3tm2Nrm Genetic Background: involves: C3H * C57BL/6 * C57BL/6NHsd
Allelic Composition: Hoxa3tm1Nrm/Hoxa3tm1Mrc Genetic Background: involves: 129S7/SvEvBrd * C3H * C57BL/6 * C57BL/6NHsd
Allelic Composition: Hoxa3tm1Nrm/Hoxa3tm1Nrm Genetic Background: involves: C3H * C57BL/6 * C57BL/6NHsd
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MP:0004607 | abnormal cervical atlas morphology | "any structural anomaly of the first (topmost, C1) cervical vertebra which supports the globe of the head" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm1Mrc,Hoxb3tm1Mrc/Hoxb3tm1Mrc Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6J
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MP:0004608 | abnormal cervical axis morphology | "any structural anomaly of the second cervical vertebra (C2) which forms the pivot upon which the first cervical (atlas, C1) vertebra rotates" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm1Mrc,Hoxb3tm1Mrc/Hoxb3tm1Mrc Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6J
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MP:0004914 | absent ultimobranchial body | "absence of the sac-like structure emanating from the caudal-most branchial pouch of the embryo which develops into the lateral portion of the thyroid" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm1Mrc,Hoxb3tm1Mrc/Hoxb3tm1Mrc Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6J
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MP:0005269 | abnormal occipital bone morphology | "anomalous structure of the bone at the lower, posterior part of the skull" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm1Mrc,Hoxb3tm1Mrc/Hoxb3tm1Mrc Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6J
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MP:0005298 | abnormal clavicle morphology | "malformation of the doubly curved long bone that forms part of the shoulder girdle and articulates with the sternum and the scapula" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
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MP:0005406 | abnormal heart size | "change from the norm in the physical magnitude of the cardiac muscle or any of its component structures" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
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MP:0005508 | abnormal skeleton morphology | "malformation of the bony framework of the body in vertebrates" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
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MP:0006009 | abnormal neuronal migration | "defective or impaired movement of immature neurons from germinal zones to specific positions where they will reside as they mature" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Hoxa3tm3Mrc/Hoxa3tm3Mrc,Hoxd3tm2Mrc/Hoxd3tm2Mrc Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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MP:0006117 | aortic valve stenosis | "abnormal narrowing of the aortic valve" [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
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MP:0006340 | abnormal fourth branchial arch morphology | "anomaly in the structure of the fourth arch which contributes to development of the cartilage of the larynx, laryngeal, pharyngeal, and soft palate muscles, superior parathyroid gland, and C-cells of the thymus" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator", zillmusom:http://musom.marshall.edu/anatomy/grosshom/z_devbranc.html] |
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Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
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MP:0006354 | abnormal fourth branchial arch artery morphology | "any structural anomaly of the vessels formed within the fourth pair of branchial arches in embryogenesis" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Fgf8tm1Mrc/Fgf8tm2Mrc,Hoxa3tm1(cre)Moon/Hoxa3+ Genetic Background: involves: 129/Sv * C57BL/6
Allelic Composition: Fgf8tm1Mrc/Fgf8tm1Moon,Hoxa3tm1(cre)Moon/Hoxa3+ Genetic Background: involves: 129/Sv * C57BL/6
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MP:0009052 | anal stenosis | "abnormal narrowing or constriction of the anal orifice" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Bmp4tm4Blh/Bmp4+,Bmp7tm1.1Dgra/Bmp7tm1.1Dgra,Hoxa3tm1(cre)Moon/Hoxa3+ Genetic Background: involves: 129S6/SvEvTac * C57BL/6NTac
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MP:0009252 | absent urinary bladder | "absence of the inflatable musculomembranous bag for holding urine" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Bmp4tm4Blh/Bmp4+,Bmp7tm1.1Dgra/Bmp7tm1.1Dgra,Hoxa3tm1(cre)Moon/Hoxa3+ Genetic Background: involves: 129S6/SvEvTac * C57BL/6NTac
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MP:0009844 | abnormal neural crest cell apoptosis | "change in the timing or the number of neural crest cells undergoing programmed cell death" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Fgf8tm1Mrc/Fgf8tm2Mrc,Hoxa3tm1(cre)Moon/Hoxa3+ Genetic Background: involves: 129/Sv * C57BL/6
Allelic Composition: Fgf8tm1Mrc/Fgf8tm1Moon,Hoxa3tm1(cre)Moon/Hoxa3+ Genetic Background: involves: 129/Sv * C57BL/6
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MP:0009913 | abnormal hyoid bone greater horn morphology | "any structural anomaly of the larger and more lateral of the paired processes on either side of the hyoid bone" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm1Mrc,Hoxb3tm1Mrc/Hoxb3tm1Mrc Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6J
Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm2Nrm Genetic Background: involves: 129S7/SvEvBrd * C3H * C57BL/6 * C57BL/6NHsd
Allelic Composition: Hoxa3tm2Nrm/Hoxa3tm2Nrm Genetic Background: involves: C3H * C57BL/6 * C57BL/6NHsd
Allelic Composition: Hoxa3tm1Nrm/Hoxa3tm1Mrc Genetic Background: involves: 129S7/SvEvBrd * C3H * C57BL/6 * C57BL/6NHsd
Allelic Composition: Hoxa3tm1Nrm/Hoxa3tm1Nrm Genetic Background: involves: C3H * C57BL/6 * C57BL/6NHsd
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MP:0009914 | abnormal hyoid bone lesser horn morphology | "any structural anomaly of shorter and more medial of the paired processes on either side of the hyoid bone" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm1Mrc,Hoxb3tm1Mrc/Hoxb3tm1Mrc Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6J
Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm2Nrm Genetic Background: involves: 129S7/SvEvBrd * C3H * C57BL/6 * C57BL/6NHsd
Allelic Composition: Hoxa3tm2Nrm/Hoxa3tm2Nrm Genetic Background: involves: C3H * C57BL/6 * C57BL/6NHsd
Allelic Composition: Hoxa3tm1Nrm/Hoxa3tm1Mrc Genetic Background: involves: 129S7/SvEvBrd * C3H * C57BL/6 * C57BL/6NHsd
Allelic Composition: Hoxa3tm1Nrm/Hoxa3tm1Nrm Genetic Background: involves: C3H * C57BL/6 * C57BL/6NHsd
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MP:0009915 | absent hyoid bone lesser horns | "absence of shorter and more medial of the paired processes on either side of the hyoid bone" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
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MP:0010371 | abnormal epiglottis morphology | "any structural anomaly of the most superior of the laryngeal cartilages, which is found at the root of the tongue and folds back over the entrance to the larynx during swallowing, preventing inhalation of food or drink" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
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MP:0010454 | abnormal truncus arteriosis septation | "anomaly in the process of dividing the common arterial trunk arising out of both heart ventricles to divide into the aorta and pulmonary artery during development" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Fgf8tm1Mrc/Fgf8tm2Mrc,Hoxa3tm1(cre)Moon/Hoxa3+ Genetic Background: involves: 129/Sv * C57BL/6
Allelic Composition: Fgf8tm1Mrc/Fgf8tm1Moon,Hoxa3tm1(cre)Moon/Hoxa3+ Genetic Background: involves: 129/Sv * C57BL/6
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MP:0010484 | bicuspid aortic valve | "the presence of two cusps in the aortic valve instead of three" [http://emedicine.medscape.com] |
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Allelic Composition: Fgf8tm1Mrc/Fgf8tm2Mrc,Hoxa3tm1(cre)Moon/Hoxa3+ Genetic Background: involves: 129/Sv * C57BL/6
Allelic Composition: Fgf8tm1Mrc/Fgf8tm1Moon,Hoxa3tm1(cre)Moon/Hoxa3+ Genetic Background: involves: 129/Sv * C57BL/6
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MP:0010527 | bicuspid pulmonary valve | "the presence of two cusps or leaflets in the pulmonary valve instead of three" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
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MP:0010541 | aorta hypoplasia | "underdevelopment or reduced size of the main trunk of the systemic arterial system that originates from the base of the left ventricle of the heart and extends to the abdomen at the point where it branches into the common iliac arteries, usually due to reduced cell number" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
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MP:0010551 | abnormal coronary vessel morphology | "any structural anomaly of any of the arteries or veins that supply blood to the heart or return blood from the heart muscles to the circulation" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Fgf8tm1Mrc/Fgf8tm2Mrc,Hoxa3tm1(cre)Moon/Hoxa3+ Genetic Background: involves: 129/Sv * C57BL/6
Allelic Composition: Fgf8tm1Mrc/Fgf8tm1Moon,Hoxa3tm1(cre)Moon/Hoxa3+ Genetic Background: involves: 129/Sv * C57BL/6
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MP:0010728 | fusion of atlas and occipital bones | "union of elements of the atlas and the bone at the lower, posterior part of the skull into one structure" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm1Mrc,Hoxb3tm1Mrc/Hoxb3tm1Mrc Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6J
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MP:0011087 | complete neonatal lethality | "death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith] |
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Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm1Mrc,Hoxb3tm1Mrc/Hoxb3tm1Mrc Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6J
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MP:0011088 | partial neonatal lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the neonatal period after birth (Mus: P0)" [MGI:csmith] |
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Allelic Composition: Fgf8tm1Mrc/Fgf8tm2Mrc,Hoxa3tm1(cre)Moon/Hoxa3+ Genetic Background: involves: 129/Sv * C57BL/6
Allelic Composition: Fgf8tm1Mrc/Fgf8tm1Moon,Hoxa3tm1(cre)Moon/Hoxa3+ Genetic Background: involves: 129/Sv * C57BL/6
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MP:0011089 | complete perinatal lethality | "death of all organisms of a given genotype in a population within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith] |
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Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
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MP:0011576 | absent cervical atlas | "absence of the first (topmost, C1) cervical vertebra which supports the globe of the head" [MGI:anna] |
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Allelic Composition: Hoxa3tm2Nrm/Hoxa3tm3.1Nrm,H2afvTg(Wnt1-cre)11Rth/0 Genetic Background: involves: C3H * C57BL/6 * CBA/J
Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm1Mrc,Hoxd3tm1Mrc/Hoxd3tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
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MP:0012491 | larynx stenosis | "abnormal narrowing or constriction of the organ of voice production located between the pharynx and the trachea" [MGI:anna] |
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Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
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MP:0013162 | abnormal thyroid gland isthmus morphology | "any structural anomaly of the narrow median bridge that joins together the lower thirds of the two lateral (right and left) lobes of the thyroid gland and usually covers the second and the third tracheal rings; the thyroid isthmus is variable in presence and size, can change shape and size, and can encompass a cranially extending pyramid lobe (lobus pyramidalis or processus pyramidalis), remnant of the thyroglossal duct" [MGI:anna] |
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Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm1Mrc,Hoxb3tm1Mrc/Hoxb3tm1Mrc Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6J
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MP:0013163 | absent thyroid gland isthmus | "absence of the narrow median bridge that joins together the lower thirds of the two lateral (right and left) lobes of the thyroid gland" [MGI:anna] |
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Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm1Mrc,Hoxb3tm1Mrc/Hoxb3tm1Mrc Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6J
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MP:0013290 | persistent ultimobranchial bodies | "partial or complete failure of the ultimobranchial bodies to fuse with the ventral thyroid primordium; as a result, ultimobranchial bodies remain as unilateral or bilateral vesicles composed exclusively of calcitonin-producing cells" [ISBN:032322153X] |
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Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm1Mrc,Hoxb3tm1Mrc/Hoxb3tm1Mrc Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6J
Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm1Mrc,Hoxd3tm1Mrc/Hoxd3tm1Mrc Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
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MP:0013574 | ectopic parathyroid gland | "a parathyroid gland located outside of its normal position; in the normal adult mouse, the parathyroids are usually found embedded in the connective tissue capsule on the posterior surface of the thyroid gland; because of their common pharyngeal pouch origin, ectopic thyroid and parathyroid tissue can occasionally be found in the thymus" [MGI:Anna] |
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Allelic Composition: Fgf8tm1Mrc/Fgf8tm2Mrc,Hoxa3tm1(cre)Moon/Hoxa3+ Genetic Background: involves: 129/Sv * C57BL/6
Allelic Composition: Fgf8tm1Mrc/Fgf8tm1Moon,Hoxa3tm1(cre)Moon/Hoxa3+ Genetic Background: involves: 129/Sv * C57BL/6
Allelic Composition: Hoxa3tm1Mrc/Hoxa3+,Hoxb3tm1Mrc/Hoxb3tm1Mrc Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6J
Allelic Composition: Hoxa3tm1Mrc/Hoxa3+,Hoxd3tm1Mrc/Hoxd3tm1Mrc Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm3.1Nrm,H2afvTg(Wnt1-cre)11Rth/0 Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J * CBA/J
Allelic Composition: Hoxa3tm2Nrm/Hoxa3tm3.1Nrm,H2afvTg(Wnt1-cre)11Rth/0 Genetic Background: involves: C3H * C57BL/6 * CBA/J
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MP:0030291 | short soft palate | "reduced length of the musculomembranous fold that partly separates the mouth and pharynx, located behind the hard palate in the adult" [MGI:anna] |
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Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
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MP:0030337 | enlarged third pharyngeal arch artery | "increased size of the third pharyngeal arch artery" [MGI:anna] |
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Allelic Composition: Fgf8tm1Mrc/Fgf8tm2Mrc,Hoxa3tm1(cre)Moon/Hoxa3+ Genetic Background: involves: 129/Sv * C57BL/6
Allelic Composition: Fgf8tm1Mrc/Fgf8tm1Moon,Hoxa3tm1(cre)Moon/Hoxa3+ Genetic Background: involves: 129/Sv * C57BL/6
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