MP:0000018 | small ears | "outer ears of a smaller than normal size" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Pitx2tm1Kki/Pitx2tm1Kki Genetic Background: involves: 129P2/OlaHsd * C57BL
Allelic Composition: Hoxa2tm1Ipc/Hoxa2tm1.1Fmr,Tg(CAG-cre/ERT2)F34Fmr/0 Genetic Background: involves: 129/Sv * 129S2/SvPas * C57BL/6 * CD-1
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MP:0000029 | abnormal malleus morphology | "structural anomaly in the largest of the three auditory ossicles, which resembles a club or hammer " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4tm1Rwi Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd
Allelic Composition: Hoxa2tm1Grid/Hoxa2tm1Grid Genetic Background: involves: 129S/SvEv * 129S1/Sv * C57BL/6 * DBA/2
Allelic Composition: Hoxa2tm1(tetO)Mllo/Hoxa2tm1Grid Genetic Background: involves: 129S1/Sv * C57BL/6J
Allelic Composition: Hoxa2tm1Grid/Hoxa2+ Genetic Background: involves: 129S1/Sv
Allelic Composition: Hoxa2tm1.1Fmr/Hoxa2tm1.1Fmr,H2afvTg(Wnt1-cre)11Rth/0 Genetic Background: involves: 129/Sv * C57BL/6J * CBA/J
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MP:0000030 | abnormal tympanic ring morphology | "malformed bony ring at the ear canal to which the tympanic membrane is attached" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:23837] |
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Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4tm1Rwi Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd
Allelic Composition: Hoxa2tm1Grid/Hoxa2tm1Grid Genetic Background: involves: 129S1/Sv * C57BL/6J
Allelic Composition: Hoxa2tm1(tetO)Mllo/Hoxa2tm1Grid Genetic Background: involves: 129S1/Sv * C57BL/6J
Allelic Composition: Hoxa2tm1.1Fmr/Hoxa2tm1.1Fmr,H2afvTg(Wnt1-cre)11Rth/0 Genetic Background: involves: 129/Sv * C57BL/6J * CBA/J
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MP:0000039 | abnormal otic capsule morphology | "malformation of the cartilage or bony capsule surrounding the inner ear mechanism" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:23837] |
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Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4tm1Rwi Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd
Allelic Composition: Hoxa2tm1Grid/Hoxa2tm1Grid Genetic Background: involves: 129S/SvEv * 129S1/Sv * C57BL/6 * DBA/2
Allelic Composition: Hoxa2tm1(tetO)Mllo/Hoxa2tm1Grid Genetic Background: involves: 129S1/Sv * C57BL/6J
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MP:0000049 | abnormal middle ear morphology | "malformation or malfunction of any components of the tympanic cavity or its ossicles" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Hoxa2tm1.1Fmr/Hoxa2tm1.1Fmr,Tg(CAG-cre/ERT2)F34Fmr/0 Genetic Background: involves: 129/Sv * C57BL/6 * CD-1
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MP:0000079 | abnormal basioccipital bone morphology | "malformed basilar process of the occipital bone" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:55583] |
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Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4tm1Rwi Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd
Allelic Composition: Hoxa1tm1Mrc/Hoxa1tm2Mrc,Hoxa2tm1Mrc/Hoxa2+ Genetic Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ
Allelic Composition: Hoxa2tm1Mrc/Hoxa2tm1Mrc Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Hoxa2tm1Grid/Hoxa2tm1Grid Genetic Background: involves: 129S1/Sv * C57BL/6J
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MP:0000106 | abnormal basisphenoid bone morphology | "malformed base of the sphenoid bone" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:55583] |
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Allelic Composition: Hoxa2tm1Grid/Hoxa2tm1Grid Genetic Background: involves: 129S1/Sv
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MP:0000111 | cleft palate | "congenital fissure of the tissues normally uniting to form the palate" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840] |
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Allelic Composition: Hoxa2tm1(tetO)Mllo/Hoxa2tm1(tetO)Mllo Genetic Background: involves: 129S1/Sv * C57BL/6J
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MP:0000164 | abnormal cartilage development | "anomalous formation of the nonvascular, resilient, flexible connective tissue found primarily in joints, walls of the throax, and tubular structures, but which also comprises most of the skeleton in early fetal life " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4tm1Rwi Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd
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MP:0000428 | abnormal craniofacial morphology | "anomalous structure or development of the face and/or cranium" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Hoxa2tm1.1Fmr/Hoxa2tm1.1Fmr Genetic Background: involves: 129/Sv * C57BL/6 * SJL
Allelic Composition: Hoxa2tm2Fmr/Hoxa2tm2Fmr Genetic Background: involves: 129S2/SvPas
Allelic Composition: Hoxa2tm2.1Fmr/Hoxa2tm2.1Fmr Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL
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MP:0000438 | abnormal skull morphology | "anomalous structure or development of the cranium" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Pitx2tm1Kki/Pitx2tm1Kki Genetic Background: involves: 129P2/OlaHsd * C57BL
Allelic Composition: Hoxa2tm1Mrc/Hoxa2tm1Mrc Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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MP:0000841 | abnormal hindbrain morphology | "malformed caudal region of the brain; includes cerebellum, pons and medulla oblongata" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:45302] |
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Allelic Composition: Hoxa1tm1Mrc/Hoxa1tm2Mrc,Hoxa2tm1Mrc/Hoxa2+ Genetic Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ
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MP:0000909 | abnormal facial motor nucleus morphology | "malformation or disorganization of the group of motor neurons residing in the pons that innervate the muscles of facial expression" [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3] |
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Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4tm1Rwi Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd
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MP:0000913 | abnormal brain development | "malformed or incomplete differentiation of the brain" [MGI:cls, J:49840] |
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Allelic Composition: Gt(ROSA)26Sortm1(Hoxa2)Fmr/Gt(ROSA)26Sor+,Olig2tm2(TVA,cre)Rth/Olig2+ Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Hoxa2tm1.1Fmr/Hoxa2tm1.1Fmr,Tg(CAG-cre/ERT2)F34Fmr/0 Genetic Background: involves: 129 * CD-1
Allelic Composition: Hoxa2tm2.1Fmr/Hoxa2tm2.1Fmr,Hoxb2tm2.2Fmr/Hoxb2tm2.2Fmr Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL
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MP:0000933 | abnormal rhombomere morphology | "malformation of the transverse segments in the hindbrain region of the developing neural tube" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:1776] |
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Allelic Composition: Gopctm1.1Tno/Gopctm1.1Tno Genetic Background: involves: 129S4/SvJae * C57BL/6
Allelic Composition: Hoxa2tm1(tetO)Mllo/Hoxa2tm1(tetO)Mllo Genetic Background: involves: 129S1/Sv
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MP:0000954 | reduced oligodendrocyte progenitor number | "fewer cells that differentiate into a type of glial cell in the central nervous system" [J:15108] |
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Allelic Composition: Hoxa2tm2.1Fmr/Hoxa2tm2.1Fmr,Hoxb2tm2.2Fmr/Hoxb2tm2.2Fmr Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL
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MP:0000966 | reduced sensory neuron number | "fewer than normal numbers of cells that innervate an effector (muscle or glandular) tissue" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:60159] |
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Allelic Composition: Aspatm1Mata/Aspatm1Mata Genetic Background: involves: 129S5/SvEvBrd
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MP:0001071 | abnormal facial nerve morphology | "malformed or misprojection of motor axons from the pons to the face" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:29973] |
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Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4tm1Rwi Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd
Allelic Composition: Hoxa2tm1Grid/Hoxa2tm1Grid Genetic Background: involves: 129S1/Sv * C57BL/6J
Allelic Composition: Hoxa2tm1(tetO)Mllo/Hoxa2tm1Grid Genetic Background: involves: 129S1/Sv * C57BL/6J
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MP:0001073 | abnormal glossopharyngeal nerve morphology | "malformed or misprojection of sensory and autonomic axons to the parotid gland, carotid body, posterior third of the tongue" [Principles of Neural Science:ISBN 0-8385-8034-3, J:33038] |
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Allelic Composition: Hoxa2tm1Grid/Hoxa2tm1Grid Genetic Background: involves: 129S1/Sv * C57BL/6J
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MP:0001074 | abnormal vagus nerve morphology | "malformed or misprojection of autonomic, sensory and motor axons of the tenth cranial nerve to the pharynx, larynx, trachea, lungs, heart and GI tract" [Principles of Neural Science:ISBN 0-8385-8034-3, J:33038] |
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Allelic Composition: Hoxa2tm1Grid/Hoxa2tm1Grid Genetic Background: involves: 129S1/Sv * C57BL/6J
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MP:0001436 | abnormal suckling behavior | "reduced ability or inability to exert suction by the mouth, or atypical suckling pattern" [J:16461] |
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Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4tm1Rwi Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd
Allelic Composition: Hoxa2tm1Mrc/Hoxa2tm1Mrc Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Hoxa1tm2Mrc/Hoxa1+,Hoxa2tm1Mrc/Hoxa2tm1Mrc Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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MP:0001438 | aphagia | "inability to eat " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:30404] |
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Allelic Composition: Hoxa2tm1Grid/Hoxa2tm1Grid Genetic Background: involves: 129S1/Sv * C57BL/6J
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MP:0001732 | postnatal growth retardation | "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Hoxa2tm1(tetO)Mllo/Hoxa2tm1(tetO)Mllo Genetic Background: involves: 129S1/Sv
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MP:0001953 | respiratory failure | "cessation of or failure to commence breathing" [MGI:cls, J:60159] |
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Allelic Composition: Pitx2tm1Kki/Pitx2tm1Kki Genetic Background: involves: 129P2/OlaHsd * C57BL
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MP:0002102 | abnormal ear morphology | "structural or developmental anomaly of any of the structures involved in the ear or vestibular system" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Hoxa2tm1.1Fmr/Hoxa2tm1.1Fmr Genetic Background: involves: 129/Sv * C57BL/6 * SJL
Allelic Composition: Hoxa2tm2Fmr/Hoxa2tm2Fmr Genetic Background: involves: 129S2/SvPas
Allelic Composition: Hoxa2tm2.1Fmr/Hoxa2tm2.1Fmr Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL
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MP:0002113 | abnormal skeleton development | "anomalous differentiation or remodeling of bone tissue resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4tm1Rwi Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd
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MP:0002116 | abnormal craniofacial bone morphology | "abnormal development of cranial or facial bones resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4tm1Rwi Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd
Allelic Composition: Hoxa2tm1.1Fmr/Hoxa2tm1.1Fmr,Tg(CAG-cre/ERT2)F34Fmr/0 Genetic Background: involves: 129/Sv * C57BL/6 * CD-1
Allelic Composition: Hoxa2tm1.1Fmr/Hoxa2tm1.1Fmr,H2afvTg(Wnt1-cre)11Rth/0 Genetic Background: involves: 129/Sv * C57BL/6J * CBA/J
Allelic Composition: Hoxa2tm1Ipc/Hoxa2tm1.1Fmr,Tg(CAG-cre/ERT2)F34Fmr/0 Genetic Background: involves: 129/Sv * 129S2/SvPas * C57BL/6 * CD-1
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MP:0002169 | no phenotype detected | "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Hoxa1tm2Mrc/Hoxa1+,Hoxa2tm1Mrc/Hoxa2+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Hoxa2tm1.1Fmr/Hoxa2tm1.1Fmr Genetic Background: involves: 129/Sv * C57BL/6 * SJL
Allelic Composition: Hoxa2tm1Fmr/Hoxa2+ Genetic Background: involves: 129/Sv * C57BL/6
Allelic Composition: Hoxa2tm1.1Fmr/Hoxa2tm1.1Fmr,Tg(CAG-cre/ERT2)F34Fmr/0 Genetic Background: involves: 129/Sv * C57BL/6 * CD-1
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MP:0002177 | abnormal outer ear morphology | "malformation or malfunction of any components of the auricles or external acoustic meatus" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Pbx3tm1.1Og/Pbx3tm1.1Og Genetic Background: involves: 129S4/SvJae * C57BL/6
Allelic Composition: Hoxa2tm1(tetO)Mllo/Hoxa2tm1Grid Genetic Background: involves: 129S1/Sv * C57BL/6J
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MP:0003056 | abnormal hyoid bone | "anomalous structure of the U-shaped bone lying between the mandible and the larynx that supports the tongue muscles" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8, hdene:Howard Dene, Mouse Genome Informatics Curator] |
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Allelic Composition: Hoxa2tm1Grid/Hoxa2tm1Grid Genetic Background: involves: 129S1/Sv * C57BL/6J
Allelic Composition: Hoxa2tm1.1Fmr/Hoxa2tm1.1Fmr,H2afvTg(Wnt1-cre)11Rth/0 Genetic Background: involves: 129/Sv * C57BL/6J * CBA/J
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MP:0003110 | absent malleal processus brevis | |
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Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4tm1Rwi Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd
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MP:0003168 | abnormal scala vestibuli morphology | "any malformation or absence of the division of the spiral canal of the cochlea lying on the apical side of the spiral lamina and vestibular membrane" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator] |
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Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4tm1Rwi Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd
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MP:0003632 | abnormal nervous system morphology | |
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Allelic Composition: Hoxa2tm1.1Fmr/Hoxa2tm1.1Fmr Genetic Background: involves: 129/Sv * C57BL/6 * SJL
Allelic Composition: Hoxa2tm2Fmr/Hoxa2tm2Fmr Genetic Background: involves: 129S2/SvPas
Allelic Composition: Hoxa2tm2.1Fmr/Hoxa2tm2.1Fmr Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL
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MP:0004136 | abnormal tongue muscle morphology | "anomalous structure or development of the muscular portion of the tongue" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Hoxa2tm1Mrc/Hoxa2tm1Mrc Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Hoxa2tm1(tetO)Mllo/Hoxa2tm1(tetO)Mllo Genetic Background: involves: 129S1/Sv * C57BL/6J
Allelic Composition: Hoxa2tm1(tetO)Mllo/Hoxa2tm1Grid Genetic Background: involves: 129S1/Sv * C57BL/6J
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MP:0004204 | absent stapes | "absence of the smallest and innermost of the three auditory ossicles" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4tm1Rwi Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd
Allelic Composition: Hoxa1tm1Mrc/Hoxa1tm2Mrc,Hoxa2tm1Mrc/Hoxa2+ Genetic Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ
Allelic Composition: Hoxa2tm1Grid/Hoxa2tm1Grid Genetic Background: involves: 129S1/Sv * C57BL/6J
Allelic Composition: Hoxa2tm1(tetO)Mllo/Hoxa2tm1Grid Genetic Background: involves: 129S1/Sv * C57BL/6J
Allelic Composition: Hoxa2tm1.1Fmr/Hoxa2tm1.1Fmr,H2afvTg(Wnt1-cre)11Rth/0 Genetic Background: involves: 129/Sv * C57BL/6J * CBA/J
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MP:0004423 | abnormal squamosal bone morphology | "any structural anomaly of the thin, platelike part of the temporal bone" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4tm1Rwi Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd
Allelic Composition: Hoxa2tm1Grid/Hoxa2tm1Grid Genetic Background: involves: 129S1/Sv
Allelic Composition: Hoxa2tm1(tetO)Mllo/Hoxa2tm1(tetO)Mllo Genetic Background: involves: 129S1/Sv * C57BL/6J
Allelic Composition: Hoxa2tm1(tetO)Mllo/Hoxa2tm1Grid Genetic Background: involves: 129S1/Sv * C57BL/6J
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MP:0004665 | abnormal stapedial artery morphology | "any structural abnormality in the small artery that passes through the ring of the stapes; while the stapedial artery is a temporary artery thought to disappear at late embryonic stage in humans, the mouse stapedial artery is complete by E13 and persists into adulthood " [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Hoxa2tm1Grid/Hoxa2tm1Grid Genetic Background: involves: 129S1/Sv
Allelic Composition: Hoxa2tm1(tetO)Mllo/Hoxa2tm1Grid Genetic Background: involves: 129S1/Sv * C57BL/6J
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MP:0004666 | absent stapedial artery | "absence of the small artery that passes through the ring of the stapes" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Hoxa2tm1(tetO)Mllo/Hoxa2tm1(tetO)Mllo Genetic Background: involves: 129S1/Sv * C57BL/6J
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MP:0004924 | abnormal behavior | "anomalies in the actions, reactions, or performance of an organism in response to external or internal stimuli compared to controls" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Hoxa2tm1.1Fmr/Hoxa2tm1.1Fmr Genetic Background: involves: 129/Sv * C57BL/6 * SJL
Allelic Composition: Hoxa2tm2Fmr/Hoxa2tm2Fmr Genetic Background: involves: 129S2/SvPas
Allelic Composition: Hoxa2tm2.1Fmr/Hoxa2tm2.1Fmr Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL
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MP:0005105 | abnormal middle ear ossicle morphology | "anomalous structure or development of the three small bones of the middle ear" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Hoxa1tm1Mrc/Hoxa1tm2Mrc,Hoxa2tm1Mrc/Hoxa2+ Genetic Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ
Allelic Composition: Hoxa2tm1Mrc/Hoxa2tm1Mrc Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Hoxa2tm1Grid/Hoxa2tm1Grid Genetic Background: involves: 129S1/Sv * C57BL/6J
Allelic Composition: Hoxa2tm1(tetO)Mllo/Hoxa2tm1(tetO)Mllo Genetic Background: involves: 129S1/Sv * C57BL/6J
Allelic Composition: Hoxa2tm1(tetO)Mllo/Hoxa2tm1Grid Genetic Background: involves: 129S1/Sv * C57BL/6J
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MP:0005106 | abnormal incus morphology | "structural anomaly of the middle of the three auditory ossicles" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:83132] |
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Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4tm1Rwi Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd
Allelic Composition: Hoxa2tm1Grid/Hoxa2tm1Grid Genetic Background: involves: 129S/SvEv * 129S1/Sv * C57BL/6 * DBA/2
Allelic Composition: Hoxa2tm1.1Fmr/Hoxa2tm1.1Fmr,H2afvTg(Wnt1-cre)11Rth/0 Genetic Background: involves: 129/Sv * C57BL/6J * CBA/J
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MP:0005107 | abnormal stapes morphology | "structural anomaly of the smallest and innermost of the three auditory ossicles" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:83132] |
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Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4tm1Rwi Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd
Allelic Composition: Hoxa2tm1(tetO)Mllo/Hoxa2tm1(tetO)Mllo Genetic Background: involves: 129S1/Sv * C57BL/6J
Allelic Composition: Hoxa2tm1Fmr/Hoxa2tm1Fmr Genetic Background: involves: 129/Sv * C57BL/6
Allelic Composition: Hoxa2tm1.1Fmr/Hoxa2tm1.1Fmr,Tg(CAG-cre/ERT2)F34Fmr/0 Genetic Background: involves: 129/Sv * C57BL/6 * CD-1
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MP:0005272 | abnormal temporal bone morphology | "anomalous structure of the large, irregular bone located at the base and side of the skull; consists of three parts at birth: squamous, tympanic, and petrous" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4tm1Rwi Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd
Allelic Composition: Hoxa2tm1Grid/Hoxa2tm1Grid Genetic Background: involves: 129S1/Sv * C57BL/6J
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MP:0005508 | abnormal skeleton morphology | "malformation of the bony framework of the body in vertebrates" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Hoxa2tm1.1Fmr/Hoxa2tm1.1Fmr Genetic Background: involves: 129/Sv * C57BL/6 * SJL
Allelic Composition: Hoxa2tm2Fmr/Hoxa2tm2Fmr Genetic Background: involves: 129S2/SvPas
Allelic Composition: Hoxa2tm2.1Fmr/Hoxa2tm2.1Fmr Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL
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MP:0005579 | absent outer ear | "missing auricles or external acoustic meatus" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:17694] |
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Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4tm1Rwi Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd
Allelic Composition: Hoxa1tm2Mrc/Hoxa1tm2Mrc,Hoxa2tm1Mrc/Hoxa2tm1Mrc Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Hoxa2tm1Mrc/Hoxa2tm1Mrc Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Hoxa2tm1Grid/Hoxa2tm1Grid Genetic Background: involves: 129S1/Sv
Allelic Composition: Hoxa2tm1.1Fmr/Hoxa2tm1.1Fmr,Tg(CAG-cre/ERT2)F34Fmr/0 Genetic Background: involves: 129/Sv * C57BL/6 * CD-1
Allelic Composition: Hoxa2tm1.1Fmr/Hoxa2tm1.1Fmr,H2afvTg(Wnt1-cre)11Rth/0 Genetic Background: involves: 129/Sv * C57BL/6J * CBA/J
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MP:0005587 | abnormal Meckel s cartilage morphology | "structural anomaly of this cartilage bar in the mandibular arch that forms a temporary supporting structure in the embryonic mandible; gives rise to middle ear bones and sphenomandibular and anterior malleolar ligaments" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:17694] |
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Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4tm1Rwi Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd
Allelic Composition: Hoxa2tm1Grid/Hoxa2tm1Grid Genetic Background: involves: 129S1/Sv * C57BL/6J
Allelic Composition: Hoxa2tm1.1Fmr/Hoxa2tm1.1Fmr,H2afvTg(Wnt1-cre)11Rth/0 Genetic Background: involves: 129/Sv * C57BL/6J * CBA/J
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MP:0006018 | abnormal tympanic membrane morphology | "any structural alterations in the thin, tense membrane forming the greater part of the lateral wall of the tympanic cavity and separating it from the external acoustic meatus; the tympanic membrane consitutes the boundary between the external and middle ear." [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, smb:Susan M Bello, Mouse Genome Informatics Curator, J:46639:] |
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Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4tm1Rwi Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd
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MP:0006033 | abnormal external auditory canal | "malformation of the canal that connects the outer and middle ear" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:57313] |
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Allelic Composition: Hoxa2tm1Grid/Hoxa2tm1Grid Genetic Background: involves: 129S1/Sv
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MP:0006208 | embryonic lethality throughout fetal growth and development | "death anytime after the completion of organogenesis but before E18.5 (E14 to less than E18.5)" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Hoxb2tm3.1Fmr/Hoxb2tm3.1Fmr Genetic Background: involves: 129S2/SvPas * C57BL/6
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MP:0008023 | abnormal styloid process morphology | "any structural abnormality in the slender needle-like pointed projection that runs downward and slightly forward from the base of the inferior surface of the petrous portion of the temporal bone where it joins the tympanic portion; it gives attachment to the styloglossus, stylohyoid, and stylopharyngeus muscles and the stylohyoid and stylomandibular ligaments" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Hoxa2tm1Grid/Hoxa2tm1Grid Genetic Background: involves: 129S1/Sv * C57BL/6J
Allelic Composition: Hoxa2tm1(tetO)Mllo/Hoxa2tm1(tetO)Mllo Genetic Background: involves: 129S1/Sv * C57BL/6J
Allelic Composition: Hoxa2tm1Grid/Hoxa2+ Genetic Background: involves: 129S1/Sv
Allelic Composition: Hoxa2tm1Fmr/Hoxa2tm1Fmr Genetic Background: involves: 129/Sv * C57BL/6
Allelic Composition: Hoxa2tm1.1Fmr/Hoxa2tm1.1Fmr,Tg(CAG-cre/ERT2)F34Fmr/0 Genetic Background: involves: 129/Sv * C57BL/6 * CD-1
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MP:0008378 | small malleal processus brevis | "reduced size of the projection extending from the base of the manubrium of the malleus which contacts the upper part of the tympanic membrane" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Hoxa2tm1(tetO)Mllo/Hoxa2tm1(tetO)Mllo Genetic Background: involves: 129S1/Sv * C57BL/6J
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MP:0008380 | abnormal gonial bone morphology | "any structural abnormality of the investing bone that lies on the surface of the malleus" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4tm1Rwi Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd
Allelic Composition: Hoxa2tm1Grid/Hoxa2tm1Grid Genetic Background: involves: 129S1/Sv
Allelic Composition: Hoxa2tm1.1Fmr/Hoxa2tm1.1Fmr,Tg(CAG-cre/ERT2)F34Fmr/0 Genetic Background: involves: 129/Sv * C57BL/6 * CD-1
Allelic Composition: Hoxa2tm1.1Fmr/Hoxa2tm1.1Fmr,H2afvTg(Wnt1-cre)11Rth/0 Genetic Background: involves: 129/Sv * C57BL/6J * CBA/J
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MP:0008383 | enlarged gonial bone | "increased size of the investing bone that lies on the surface of the malleus" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4tm1Rwi Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd
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MP:0008386 | absent styloid process | "absence of the slender needle-like pointed projection that runs downward and slightly forward from the base of the inferior surface of the petrous portion of the temporal bone to join the tympanic portion" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4tm1Rwi Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd
Allelic Composition: Hoxa2tm1(tetO)Mllo/Hoxa2tm1Grid Genetic Background: involves: 129S1/Sv * C57BL/6J
Allelic Composition: Hoxa2tm1.1Fmr/Hoxa2tm1.1Fmr,H2afvTg(Wnt1-cre)11Rth/0 Genetic Background: involves: 129/Sv * C57BL/6J * CBA/J
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MP:0009247 | meteorism | "swelling of the abdomen resulting from gas in the intestinal or peritoneal cavity" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Hoxa2tm1Grid/Hoxa2tm1Grid Genetic Background: involves: 129S1/Sv * C57BL/6J
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MP:0009890 | cleft secondary palate | "congenital fissure of the tissues normally uniting to form the secondary palate" [PMID:16680722] |
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Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4tm1Rwi Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd
Allelic Composition: Hoxa2tm1Mrc/Hoxa2tm1Mrc Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Hoxa1tm2Mrc/Hoxa1+,Hoxa2tm1Mrc/Hoxa2tm1Mrc Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Hoxa2tm1Grid/Hoxa2tm1Grid Genetic Background: involves: 129S1/Sv * C57BL/6J
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MP:0009909 | bifid tongue | "tongue is divided by a midline cleft" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4tm1Rwi Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd
Allelic Composition: Hoxa2tm1(tetO)Mllo/Hoxa2tm1(tetO)Mllo Genetic Background: involves: 129S1/Sv * C57BL/6J
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MP:0009914 | abnormal hyoid bone lesser horn morphology | "any structural anomaly of shorter and more medial of the paired processes on either side of the hyoid bone" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Hoxa2tm1(tetO)Mllo/Hoxa2tm1(tetO)Mllo Genetic Background: involves: 129S1/Sv * C57BL/6J
Allelic Composition: Hoxa2tm1(tetO)Mllo/Hoxa2tm1Grid Genetic Background: involves: 129S1/Sv * C57BL/6J
Allelic Composition: Hoxa2tm1Fmr/Hoxa2tm1Fmr Genetic Background: involves: 129/Sv * C57BL/6
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MP:0009915 | absent hyoid bone lesser horns | "absence of shorter and more medial of the paired processes on either side of the hyoid bone" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4tm1Rwi Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd
Allelic Composition: Hoxa2tm1.1Fmr/Hoxa2tm1.1Fmr,Tg(CAG-cre/ERT2)F34Fmr/0 Genetic Background: involves: 129/Sv * C57BL/6 * CD-1
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MP:0009937 | abnormal neuron differentiation | "abnormal growth or development of the cells of the nervous system that receive, conduct, and transmit impulses" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4tm1Rwi Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd
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MP:0010892 | increased oligodendrocyte progenitor number | "greater number of cells that differentiate into a type of glial cell in the central nervous system" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Gt(ROSA)26Sortm1(Hoxa2)Fmr/Gt(ROSA)26Sor+,Olig2tm2(TVA,cre)Rth/Olig2+ Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Hoxa2tm1.1Fmr/Hoxa2tm1.1Fmr,Tg(CAG-cre/ERT2)F34Fmr/0 Genetic Background: involves: 129 * CD-1
Allelic Composition: Hoxa2tm2.1Fmr/Hoxa2tm2.1Fmr,Hoxb2tm2.2Fmr/Hoxb2tm2.2Fmr Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL
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MP:0011083 | complete lethality at weaning | "premature death at weaning age of all organisms of a given genotype in a population, often due to the inability to make the transition to solid food" [MGI:csmith] |
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Allelic Composition: Hoxa2tm1Fmr/Hoxa2tm1Fmr Genetic Background: involves: 129/Sv * C57BL/6
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MP:0011087 | complete neonatal lethality | "death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith] |
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Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4tm1Rwi Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd
Allelic Composition: Hoxa1tm1Mrc/Hoxa1tm2Mrc,Hoxa2tm1Mrc/Hoxa2+ Genetic Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ
Allelic Composition: Hoxa1tm2Mrc/Hoxa1tm2Mrc,Hoxa2tm1Mrc/Hoxa2tm1Mrc Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Hoxa2tm1Mrc/Hoxa2tm1Mrc Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Hoxa1tm2Mrc/Hoxa1+,Hoxa2tm1Mrc/Hoxa2tm1Mrc Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Hoxa2tm1Ipc/Hoxa2tm1Ipc,Hoxb2tm1Fmr/Hoxb2tm1Fmr Genetic Background: involves: 129/Sv * 129S2/SvPas
Allelic Composition: Hoxa2tm1Grid/Hoxa2tm1Grid Genetic Background: involves: 129S1/Sv * C57BL/6J
Allelic Composition: Hoxa2tm1(tetO)Mllo/Hoxa2tm1(tetO)Mllo Genetic Background: involves: 129S1/Sv * C57BL/6J
Allelic Composition: Hoxa2tm1.2Fmr/Hoxa2tm1.2Fmr Genetic Background: involves: 129/Sv * C57BL/6 * SJL
Allelic Composition: Hoxa2tm2Fmr/Hoxa2tm2Fmr Genetic Background: involves: 129S2/SvPas
Allelic Composition: Hoxa2tm2.1Fmr/Hoxa2tm2.1Fmr Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL
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MP:0011089 | complete perinatal lethality | "death of all organisms of a given genotype in a population within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith] |
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Allelic Composition: Hoxa2tm1.1Fmr/Hoxa2tm1.1Fmr,Tg(CAG-cre/ERT2)F34Fmr/0 Genetic Background: involves: 129/Sv * C57BL/6 * CD-1
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MP:0012490 | abnormal cochlear VIII nucleus morphology | "any structural anomaly of two paired brainstem nuclei, the dorsal cochlear nucleus and the ventral cochlear nucleus, that lie dorsal and ventral, respectively, to the inferior cerebellar peduncle at the rostral pole of the medulla; the cochlear nuclei receive input from the cochlear nerve and send projections to the inferior colliculus, the medial geniculate, and other forebrain structures" [MGI:csmith] |
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Allelic Composition: Hoxb2tm3.1Fmr/Hoxb2tm3.1Fmr Genetic Background: involves: 129S2/SvPas * C57BL/6
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MP:0012786 | increased rhombomere 1 size | "increased size of the first transiently divided segment of the developing rhombencephalon; rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates; rhombomeres are numbered in caudal to rostral order with the first rhombomere arising next to the midbrain-hindbrain boundary, or isthmus" [MGI:anna] |
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Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4tm1Rwi Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd
Allelic Composition: Hoxa2tm1Ipc/Hoxa2tm1Ipc,Hoxb2tm1Fmr/Hoxb2tm1Fmr Genetic Background: involves: 129/Sv * 129S2/SvPas
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MP:0012788 | abnormal rhombomere 2 morphology | "any structural anomaly of the second transiently divided segment of the developing rhombencephalon; rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates; rhombomeres are numbered in caudal to rostral order" [MGI:anna, MGI:csmith, UBERON:0005569] |
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Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4tm1Rwi Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd
Allelic Composition: Hoxa2tm1(tetO)Mllo/Hoxa2tm1(tetO)Mllo Genetic Background: involves: 129S1/Sv
Allelic Composition: Hoxa2tm1Fmr/Hoxa2tm1Fmr Genetic Background: involves: 129/Sv * C57BL/6
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MP:0012792 | abnormal rhombomere 3 morphology | "any structural anomaly of the third transiently divided segment of the developing rhombencephalon; rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates; rhombomeres are numbered in caudal to rostral order" [MGI:anna, MGI:csmith, UBERON:0005507] |
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Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4tm1Rwi Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd
Allelic Composition: Hoxa2tm1(tetO)Mllo/Hoxa2tm1(tetO)Mllo Genetic Background: involves: 129S1/Sv
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MP:0012793 | decreased rhombomere 3 size | "reduced size of the third transiently divided segment of the developing rhombencephalon; rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates; rhombomeres are numbered in caudal to rostral order" [MGI:anna] |
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Allelic Composition: Hoxa2tm1Grid/Hoxa2tm1Grid Genetic Background: involves: 129S1/Sv
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MP:0012816 | abnormal rhombomere boundary morphology | "any structural anomaly of the anatomical surface separating the rhombomere segments" [MGI:csmith] |
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Allelic Composition: Hoxa2tm1Grid/Hoxa2tm1Grid Genetic Background: involves: 129S1/Sv
Allelic Composition: Hoxa2tm1Grid/Hoxa2+ Genetic Background: involves: 129S1/Sv
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MP:0030108 | abnormal incudostapedial joint morphology | "any structural anomaly of the small synovial joint located between the lenticular process on the long crus of the incus and the head of the stapes" [http://medical-dictionary.thefreedictionary.com/incudostapedial+joint] |
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Allelic Composition: Hoxa2tm1(tetO)Mllo/Hoxa2tm1(tetO)Mllo Genetic Background: involves: 129S1/Sv * C57BL/6J
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MP:0030119 | abnormal retrotympanic process morphology | "any structural anomaly of the posterior extension of the squamosal bone that lies just above the incus" [PMID:28566723] |
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Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4tm1Rwi Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd
Allelic Composition: Hoxa2tm1Grid/Hoxa2+ Genetic Background: involves: 129S1/Sv
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MP:0030123 | small middle ear ossicles | "reduced size of the three bones of the middle ear" [MGI:anna] |
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Allelic Composition: Hoxa1tm1Mrc/Hoxa1tm2Mrc,Hoxa2tm1Mrc/Hoxa2+ Genetic Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ
Allelic Composition: Hoxa1tm2Mrc/Hoxa1tm2Mrc,Hoxa2tm1Mrc/Hoxa2tm1Mrc Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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MP:0030150 | absent stylohyoid muscle | "absence of the slender suprahyoid muscle lying anterior and superior of the posterior belly of the digastric muscle that elevates and retracts the hyoid bone, elongating the floor of the mouth during swallowing" [https://en.wikipedia.org/wiki/Stylohyoid_muscle, https://en.wikipedia.org/wiki/Suprahyoid_muscles] |
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Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4tm1Rwi Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd
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MP:0030154 | abnormal tympanic cavity morphology | "any structural anomaly of the small, air-filled, mucosa-lined cavity that is located in the petrous portion of the temporal bone and houses the auditory ossicles and intratympanic muscles (tensor tympani and stapedius) as well as the chorda tympani and the tympanic plexus of nerves; it is split into two parts: the tympanic cavity proper (the space directly internal to the tympanic membrane) and the epitympanic recess or attic (the space superior to the tympanic membrane)" [] |
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Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4tm1Rwi Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd
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MP:0030158 | absent stapedius muscle | "missing the tiny muscle normally found in the pyramidal eminence on the posterior wall of the tympanic cavity, whose tendon inserts onto the neck of the stapes" [MGI:anna] |
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Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4tm1Rwi Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd
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MP:0030159 | abnormal tensor tympani muscle morphology | "any structural anomaly of the tiny striated muscle that originates superior to the pharyngotympanic tube, the sphenoid, and the temporal bone and inserts into the handle of the malleus; it tenses the tympanic membrane and dampens the movements of the auditory ossicles to prevent ear damage from loud sounds; it is innervated by the trigeminal nerve" [] |
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Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4tm1Rwi Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd
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MP:0030211 | abnormal styloglossus muscle morphology | "any structural anomaly of the paired extrinsic tongue muscle that arises from the anterior surface of the styloid process of the mastoid bone and the proximal quarter of the stylohyoid ligament; it passes inferiorly and anteriorly to insert into the side and inferior aspects of the tongue; the muscle fibers of styloglossus merge with those of the hyoglossus; its action aids to retract the tongue and draw up the sides of the tongue to create a trough for swallowing" [https://www.gpnotebook.co.uk/simplepage.cfm?ID=503709774, MGI:anna] |
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Allelic Composition: Hoxa2tm1Mrc/Hoxa2tm1Mrc Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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MP:0030227 | abnormal tubotympanic recess morphology | "any structural morphology of the elongate recess derived from the first pharyngeal pouch; its distal part contributes to the formation of the tympanic membrane, its proximal part elongates to form the auditory tube, and its cavity gives rise to the tympanic cavity and mastoid antrum" [http://medicine.academic.ru/156417/tubotympanic_recess, MGI:anna] |
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Allelic Composition: Hoxa2tm1Grid/Hoxa2tm1Grid Genetic Background: involves: 129S1/Sv * C57BL/6J
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MP:0030320 | abnormal temporal bone tympanic part morphology | "any structural anomaly of the curved plate of bone that is situated inferiorly to the squamous part and anteriorly to the mastoid part of the temporal bone; it surrounds the external auditory meatus, forming the anterior wall, floor and some of the posterior wall of the bony external acoustic meatus; its lateral border gives the attachment to the cartilaginous part of the external acoustic meatus; its anteroinferior surface forms the posterior boundary of the mandibular fossa" [https://en.wikipedia.org/wiki/Tympanic_part_of_the_temporal_bone, https://radiopaedia.org/articles/tympanic-part-of-temporal-bone] |
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Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4tm1Rwi Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd
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