ENSG00000134061


Homo sapiens

Features
Gene ID: ENSG00000134061
  
Biological name :CD180
  
Synonyms : CD180 / CD180 molecule / Q99467
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: -1
Band: q12.3
Gene start: 67179613
Gene end: 67196799
  
Corresponding Affymetrix probe sets: 206206_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000256447
NCBI entrez gene - 4064     See in Manteia.
OMIM - 602226
RefSeq - NM_005582
RefSeq Peptide - NP_005573
swissprot - Q99467
Ensembl - ENSG00000134061
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cd180ENSDARG00000093750Danio rerio
 CD180ENSGALG00000023411Gallus gallus
 Cd180ENSMUSG00000021624Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TLR8 / Q9NR97 / toll like receptor 8ENSG0000010191625
AC097637.1ENSG0000017336625
TLR9 / Q9NR96 / toll like receptor 9ENSG0000023973225
TLR7 / Q9NYK1 / toll like receptor 7ENSG0000019666424
TLR4 / O00206 / toll like receptor 4ENSG0000013686920
TLR5 / O60602 / toll like receptor 5ENSG0000018755419
TLR3 / O15455 / toll like receptor 3ENSG0000016434219
TLR10 / Q9BXR5 / toll like receptor 10ENSG0000017412315
TLR6 / Q9Y2C9 / toll like receptor 6ENSG0000017413015
TLR2 / O60603 / toll like receptor 2ENSG0000013746215
TLR1 / Q15399 / toll like receptor 1ENSG0000017412514


Protein motifs (from Interpro)
Interpro ID Name
 IPR000483  Cysteine-rich flanking region, C-terminal
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002224 toll-like receptor signaling pathway IBA
 biological_processGO:0002322 B cell proliferation involved in immune response IEA
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0006954 inflammatory response IBA
 biological_processGO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway IEA
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0071222 cellular response to lipopolysaccharide IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Toll Like Receptor 4 (TLR4) Cascade


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000112799 LY86 / O95711 / lymphocyte antigen 86  / complex






 

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