ENSG00000137273


Homo sapiens

Features
Gene ID: ENSG00000137273
  
Biological name :FOXF2
  
Synonyms : forkhead box F2 / FOXF2 / Q12947
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: 1
Band: p25.3
Gene start: 1389576
Gene end: 1395603
  
Corresponding Affymetrix probe sets: 206377_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000496415
Ensembl peptide - ENSP00000259806
NCBI entrez gene - 2295     See in Manteia.
OMIM - 603250
RefSeq - NM_001452
RefSeq Peptide - NP_001443
swissprot - Q12947
Ensembl - ENSG00000137273
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 foxf2aENSDARG00000017195Danio rerio
 foxf2bENSDARG00000070389Danio rerio
 FOXF2ENSGALG00000031920Gallus gallus
 Foxf2ENSMUSG00000038402Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FOXF1 / Q12946 / forkhead box F1ENSG0000010324149
FOXD3 / Q9UJU5 / forkhead box D3ENSG0000018714024
FOXD1 / Q16676 / forkhead box D1ENSG0000025149323
FOXD2 / O60548 / forkhead box D2ENSG0000018656423
FOXD4 / Q12950 / forkhead box D4ENSG0000017012222
FOXE1 / O00358 / forkhead box E1ENSG0000017891921
Q6VB84 / FOXD4L3 / forkhead box D4 like 3ENSG0000018755921
Q3SYB3 / FOXD4L6 / forkhead box D4 like 6ENSG0000027351421
Q9NU39 / FOXD4L1 / forkhead box D4 like 1ENSG0000018449221
Q5VV16 / FOXD4L5 / forkhead box D4 like 5ENSG0000020477921
Q8WXT5 / FOXD4L4 / forkhead box D4 like 4ENSG0000018465920
FOXG1 / P55316 / forkhead box G1ENSG0000017616520
FOXE3 / Q13461 / forkhead box E3ENSG0000018679019
FOXQ1 / Q9C009 / forkhead box Q1ENSG0000016437919
FOXH1 / O75593 / forkhead box H1ENSG0000016097318
AC187653.1ENSG0000024876716
FOXP4 / Q8IVH2 / forkhead box P4ENSG0000013716616
FOXP1 / Q9H334 / forkhead box P1ENSG0000011486114
FOXP2 / O15409 / forkhead box P2ENSG0000012857314
FOXP3 / Q9BZS1 / forkhead box P3ENSG0000004976812


Protein motifs (from Interpro)
Interpro ID Name
 IPR001766  Fork head domain
 IPR018122  Fork head domain conserved site1
 IPR030456  Fork head domain conserved site 2
 IPR036388  Winged helix-like DNA-binding domain superfamily
 IPR036390  Winged helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001837 epithelial to mesenchymal transition NAS
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0009653 anatomical structure morphogenesis IBA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0030198 extracellular matrix organization IMP
 biological_processGO:0042249 establishment of planar polarity of embryonic epithelium IMP
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IDA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IDA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 biological_processGO:0048566 embryonic digestive tract development IGI
 biological_processGO:0048596 embryonic camera-type eye morphogenesis IMP
 biological_processGO:0048806 genitalia development IMP
 biological_processGO:0060021 roof of mouth development IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005667 transcription factor complex IDA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding ISM
 molecular_functionGO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IMP
 molecular_functionGO:0003677 DNA binding IDA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IDA
 molecular_functionGO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding IBA
 molecular_functionGO:0008134 transcription factor binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr