ENSG00000251493


Homo sapiens

Features
Gene ID: ENSG00000251493
  
Biological name :FOXD1
  
Synonyms : forkhead box D1 / FOXD1 / Q16676
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: -1
Band: q13.2
Gene start: 73444827
Gene end: 73448527
  
Corresponding Affymetrix probe sets: 206307_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000481581
NCBI entrez gene - 2297     See in Manteia.
OMIM - 601091
RefSeq - NM_004472
RefSeq Peptide - NP_004463
swissprot - Q16676
Ensembl - ENSG00000251493
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 foxd1ENSDARG00000029179Danio rerio
 foxd2ENSDARG00000058133Danio rerio
 foxd5ENSDARG00000042485Danio rerio
 zgc:162612ENSDARG00000079699Danio rerio
 Foxd1ENSMUSG00000078302Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FOXD2 / O60548 / forkhead box D2ENSG0000018656445
FOXD3 / Q9UJU5 / forkhead box D3ENSG0000018714042
Q9NU39 / FOXD4L1 / forkhead box D4 like 1ENSG0000018449231
Q6VB84 / FOXD4L3 / forkhead box D4 like 3ENSG0000018755930
Q3SYB3 / FOXD4L6 / forkhead box D4 like 6ENSG0000027351430
Q8WXT5 / FOXD4L4 / forkhead box D4 like 4ENSG0000018465930
Q5VV16 / FOXD4L5 / forkhead box D4 like 5ENSG0000020477930
FOXD4 / Q12950 / forkhead box D4ENSG0000017012229
FOXE1 / O00358 / forkhead box E1ENSG0000017891926
FOXE3 / Q13461 / forkhead box E3ENSG0000018679023
FOXG1 / P55316 / forkhead box G1ENSG0000017616523
FOXF2 / Q12947 / forkhead box F2ENSG0000013727322
FOXQ1 / Q9C009 / forkhead box Q1ENSG0000016437922
FOXF1 / Q12946 / forkhead box F1ENSG0000010324119
AC187653.1ENSG0000024876719
FOXH1 / O75593 / forkhead box H1ENSG0000016097316
FOXP2 / O15409 / forkhead box P2ENSG0000012857315
FOXP4 / Q8IVH2 / forkhead box P4ENSG0000013716614
FOXP1 / Q9H334 / forkhead box P1ENSG0000011486113
FOXP3 / Q9BZS1 / forkhead box P3ENSG000000497689


Protein motifs (from Interpro)
Interpro ID Name
 IPR001766  Fork head domain
 IPR018122  Fork head domain conserved site1
 IPR030456  Fork head domain conserved site 2
 IPR036388  Winged helix-like DNA-binding domain superfamily
 IPR036390  Winged helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001658 branching involved in ureteric bud morphogenesis IEA
 biological_processGO:0001822 kidney development IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0007411 axon guidance IEA
 biological_processGO:0009653 anatomical structure morphogenesis IBA
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0030513 positive regulation of BMP signaling pathway IEA
 biological_processGO:0032275 luteinizing hormone secretion IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0060678 dichotomous subdivision of terminal units involved in ureteric bud branching IEA
 biological_processGO:0072076 nephrogenic mesenchyme development IEA
 biological_processGO:0072210 metanephric nephron development IEA
 biological_processGO:0072213 metanephric capsule development IEA
 biological_processGO:0072267 metanephric capsule specification IEA
 biological_processGO:0072268 pattern specification involved in metanephros development IEA
 biological_processGO:0090184 positive regulation of kidney development IEA
 cellular_componentGO:0005634 nucleus IBA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IBA
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IDA
 molecular_functionGO:0003700 DNA-binding transcription factor activity TAS
 molecular_functionGO:0008301 DNA binding, bending IDA
 molecular_functionGO:0043565 sequence-specific DNA binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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